Catalog No.
RVV15201
Species reactivity
Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Envelope glycoprotein GP350, BLLF1, Membrane antigen, MA, BLLF1
Concentration
2.37 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03200
Applications
ELISA, FCM, IF, IHC, Neutralization
Form
Liquid
Storage buffer
100 mM Pro-Ac, 20 mM Arg, pH 5.0
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
72A1
Peptides designed to spatially depict the Epstein-Barr virus major virion glycoprotein gp350 neutralization epitope elicit antibodies that block virus-neutralizing antibody 72A1 interaction with the native gp350 molecule. PMID: 25694592
Construction and Characterization of a Humanized Anti-Epstein-Barr Virus gp350 Antibody with Neutralizing Activity in Cell Culture. PMID: 29642526
Identification of three gp350/220 regions involved in Epstein-Barr virus invasion of host cells. PMID: 16087675
Identification of multiple potent neutralizing and non-neutralizing antibodies against Epstein-Barr virus gp350 protein with potential for clinical application and as reagents for mapping immunodominant epitopes. PMID: 31377598
Epstein-Barr Virus gp350 Can Functionally Replace the Rhesus Lymphocryptovirus Major Membrane Glycoprotein and Does Not Restrict Infection of Rhesus Macaques. PMID: 26559839
Inhibition of Epstein-Barr virus (EBV) release from P3HR-1 and B95-8 cell lines by monoclonal antibodies to EBV membrane antigen gp350/220. PMID: 2839689
A mouse monoclonal antibody against Epstein-Barr virus envelope glycoprotein 350 prevents infection both in vitro and in vivo. PMID: 16897655
Identification of the critical attribute(s) of EBV gp350 antigen required for elicitation of a neutralizing antibody response in vivo. PMID: 26485517
A novel vaccine candidate based on chimeric virus-like particle displaying multiple conserved epitope peptides induced neutralizing antibodies against EBV infection. PMID: 32483413
Epstein-Barr virus promotes human monocyte survival and maturation through a paracrine induction of IFN-alpha. PMID: 15210790
Molecular basis of the interaction between complement receptor type 2 (CR2/CD21) and Epstein-Barr virus glycoprotein gp350. PMID: 18786993
Binding of the endogenously expressed Epstein-Barr virus (EBV) envelope glycoprotein gp350 with the viral receptor masks the major EBV-neutralizing epitope and affects gp350-specific ADCC. PMID: 9715258
A single epitope of Epstein-Barr Virus stimulate IgG production in mice. PMID: 30294429
Effect of monoclonal antibodies to Epstein-Barr virus envelope glycoproteins on Epstein-Barr virus neutralization and binding to target cell receptors. A comparative analysis. PMID: 1703135
A high-throughput neutralizing assay for antibodies and sera evaluation against Epstein-Barr virus. PMID: 36424667
High Level Estradiol Induces EBV Reactivation and EBV gp350/220(+)CD138(+) Double-positive B Cell Population in Graves' Disease Patients and Healthy Controls. PMID: 31341401
Soluble gp350/220 and deletion mutant glycoproteins block Epstein-Barr virus adsorption to lymphocytes. PMID: 2460635
Epstein-Barr virus induces MCP-1 secretion by human monocytes via TLR2. PMID: 17522215
Intracellular synthesis of Epstein-Barr virus membrane antigen gp350/220. Inhibitory effect of monensin on its expression. PMID: 2542183
Characterization of a 70-kDa, EBV gp350/220-binding protein on HSB-2 T cells. PMID: 7963519
Neutralizing antibodies against Epstein-Barr virus infection of B cells can protect from oral viral challenge in the rhesus macaque animal model. PMID: 34337567
High level of transgene expression in primary chronic lymphocytic leukemia cells using helper-virus-free recombinant Epstein-Barr virus vectors. PMID: 12591274
Epstein-Barr virus induces GM-CSF synthesis by monocytes: effect on EBV-induced IL-1 and IL-1 receptor antagonist production in neutrophils. PMID: 9400607
The IL-1 and IL-1 receptor antagonist (IL-1Ra) response of human neutrophils to EBV stimulation. Preponderance of IL-Ra detection. PMID: 8648138
Plate fixation of talar neck fractures: preliminary review of a new technique in twenty-three patients. PMID: 11927801
Survey of Epstein Barr virus (EBV) immunogenic proteins and their epitopes: implications for vaccine preparation., PMID:25164057
Epstein-Barr viruses that express a CD21 antibody provide evidence that gp350's functions extend beyond B-cell surface binding., PMID:19889766
Aberrant Epstein-Barr viral infection in systemic lupus erythematosus., PMID:19167523
[Expression of Epstein-Barr virus membrane antigen induces lymphoma in transgenic mice]., PMID:11798890
[Epstein-Barr virus replication in Hodgkin disease]., PMID:7894116
Demonstration of Epstein-Barr virus replication in Reed-Sternberg cells of Hodgkin's disease., PMID:8393354
Expression of Epstein-Barr virus membrane antigen gp350/220 in E. coli and in insect cells., PMID:1329330
For research use only. Not for human or drug use.
