Catalog No.
DHD50501
Expression system
Mammalian Cells
Species reactivity
Human
Isotype
VH-VL-VH'-VL'
Clonality
Monoclonal
Target
Placental cadherin, CDH3, Cadherin-3, P-cadherin, CDHP, T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P22223 & P07766
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
Bispecific, PF-06671008, PF-6671008
Clone ID
PF 6671008
Identification and Validation of Th1-Selective Epitopes Derived from Proteins Overexpressed in Breast Cancer Stem Cells., PMID:40432134
Transcriptomic profiling and bioinformatics-driven statistical prioritization of CRC biomarkers: A step toward precision oncology., PMID:40419032
Dual blockage of P-cadherin and c-Met synergistically inhibits the growth of head and neck cancer., PMID:40392501
Spatial variation and associated genes of total hair follicle density in goats., PMID:40369759
The First Colombian Patient with CDH3-Related Hypotrichosis with Juvenile Macular Dystrophy., PMID:40330852
History of hypoxia exposure aids future cell invasion according to cell type and collagen density., PMID:40327100
P-cadherin overexpression is associated with early transformation of the Fallopian tube epithelium and aggressiveness of tubo-ovarian high-grade serous carcinoma., PMID:40320493
Oxidative Stress Regulates CDH3 Expression in Lung Cancer Cells via OGG1-Mediated SP1 Binding., PMID:40227353
Causal effect of interstitial lung disease on lung cancer risk in never-smokers and prognostic insights from Mendelian randomization and transcriptome analysis., PMID:40226450
Distinct roles of protrusions and collagen deformation in collective invasion of cancer cell types., PMID:40170350
Spatial transcriptomic profiling of the human fallopian tube epithelium reveals region-specific gene expression patterns., PMID:40158048
Synergistic potential of CDH3 in targeting CRC metastasis and enhancing immunotherapy., PMID:40155851
Altered structural and transporter-related gene expression patterns in the placenta play a role in fetal demise during Porcine reproductive and respiratory syndrome virus infection., PMID:40119254
Identification of Anoikis-Related Genes in Driving Immune-Inflammatory Responses in Ulcerative Colitis Based on Bioinformatics Analysis and Machine Learning., PMID:40059945
Identification and Validation of Biomarkers for Alzheimer's Disease Based on Akt and Wnt Signaling Pathways in Mouse Models., PMID:39992588
P-cadherin-dependent adhesions are required for single lumen formation and HGF-mediated cell protrusions during epithelial morphogenesis., PMID:39981519
Molecular characterization of a rare TP63 variant associated with split-hand/split-foot malformation 4 and incomplete penetrance: disruption of the p63-Dlx signaling pathway., PMID:39910461
Identification of Anoikis-Related Genes in Chronic Kidney Disease Based on Bioinformatics Analysis Combined with Experimental Validation., PMID:39867944
Whole-exome sequencing uncovers the genetic basis of hereditary concomitant exotropia in ten Chinese pedigrees., PMID:39773702
CDH3-AS1 antisense RNA enhances P-cadherin translation and acts as a tumor suppressor in melanoma., PMID:39764055
Dynamic changes in the skin transcriptome for the melanin pigmentation in embryonic chickens., PMID:39693959
A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer., PMID:39654063
Classical cadherins evolutionary constraints in primates is associated with their expression in the central nervous system., PMID:39570883
Serum Level of Cadherin-P (CDH3) Is a Novel Predictor of Cardiovascular Events Related to Atherosclerosis in a 3-Year Follow-Up Study., PMID:39518432
COADREADx: A comprehensive algorithmic dissection of colorectal cancer unravels salient biomarkers and actionable insights into its discrete progression., PMID:39484215
Integrative Analysis of ATAC-Seq and RNA-Seq through Machine Learning Identifies 10 Signature Genes for Breast Cancer Intrinsic Subtypes., PMID:39452108
Cadherin adhesion complexes direct cell aggregation in the epithelial transition of Wnt-induced nephron progenitor cells., PMID:39344436
CDH3 Is an Effective Serum Biomarker of Colorectal Cancer Distant Metastasis Patients., PMID:39247592
CHAI: consensus clustering through similarity matrix integration for cell-type identification., PMID:39207729
Hsa_circ_0023179 modulated the processes of proliferation, apoptosis, and EMT in non-small cell lung cancer cells via the miR-615-5p/CDH3 axis., PMID:39159001
An investigation of plasma cell-free RNA for the detection of colorectal cancer: From transcriptome marker selection to targeted validation., PMID:39146279
CDH3 Mutation-Associated Juvenile-Onset Macular Dystrophy., PMID:39046397
Associations between multiple neurological biomarkers and distal sensorimotor polyneuropathy: KORA F4/FF4 study., PMID:38872492
Prelude to malignancy: A gene expression signature in normal mammary gland from breast cancer patients suggests pre-tumorous alterations and is associated with adverse outcomes., PMID:38850108
Cadherin Adhesion Complexes Direct Cell Aggregation in the Epithelial Transition of Wnt-Induced Nephron Progenitor Cells., PMID:38654822
First Transcriptome Analysis of Hepatoblastoma in Brazil: Unraveling the Pivotal Role of Noncoding RNAs and Metabolic Pathways., PMID:38649558
Explicate molecular landscape of combined pulmonary fibrosis and emphysema through explainable artificial intelligence: a comprehensive analysis of ILD and COPD interactions using RNA from whole lung homogenates., PMID:38644448
Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing., PMID:38613320
CHAI: Consensus Clustering Through Similarity Matrix Integration for Cell-Type Identification., PMID:38562750
Predicting potential therapeutic targets and small molecule drugs for early-stage lung adenocarcinoma., PMID:38555814
Transcriptomic and proteomic study of cancer cell lines exposed to actinomycin D and nutlin-3a reveals numerous, novel candidates for p53-regulated genes., PMID:38460933
Genome-wide profiling of histone (H3) lysine 4 (K4) tri-methylation (me3) under drought, heat, and combined stresses in switchgrass., PMID:38424499
Comprehensive multiplexed autoantibody profiling of patients with advanced urothelial cancer., PMID:38309723
Molecular heterogeneity of quiescent melanocyte stem cells revealed by single-cell RNA-sequencing., PMID:38187565
Identification and validation of prognostic signature genes of bladder cancer by integrating methylation and transcriptomic analysis., PMID:38172584
Downregulated CDH3 is correlated with a better prognosis for LUAD and decreases proliferation and migration of lung cancer cells., PMID:38064156
Alteration of Cadherin 3 Expression and DNA Methylation in Association with Aggressive Renal Cell Carcinoma., PMID:38003666
Photobiomodulation Facilitates Rat Cutaneous Wound Healing by Promoting Epidermal Stem Cells and Hair Follicle Stem Cells Proliferation., PMID:37882982
Hypotrichosis with juvenile macular dystrophy with novel mutations in CDH3 gene., PMID:37850495
Dosimetry of a Novel 111Indium-Labeled Anti-P-Cadherin Monoclonal Antibody (FF-21101) in Non-Human Primates., PMID:37760501
For research use only. Not for human or drug use.
