Catalog No.
PHA33501
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human IRF6 (Glu196-Thr445).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
IRF-6,Interferon regulatory factor 6,IRF6
Purification
Purified by antigen affinity column.
Accession
O14896
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma., PMID:38378697
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy., PMID:37398248
ErbB2/Her2-dependent downregulation of a cell death-promoting protein BLNK in breast cancer cells is required for 3D breast tumor growth., PMID:35933456
Novel immune-related signature based on immune cells for predicting prognosis and immunotherapy response in clear cell renal cell carcinoma., PMID:35441741
Identification of Growth Factors, Cytokines and Mediators Regulated by Artemisia annua L. Polyphenols (pKAL) in HCT116 Colorectal Cancer Cells: TGF-β1 and NGF-β Attenuate pKAL-Induced Anticancer Effects via NF-κB p65 Upregulation., PMID:35163520
Tumor levels of the mediators of ErbB2-driven anoikis resistance correlate with breast cancer relapse in patients receiving trastuzumab-based therapies., PMID:33728523
ErbB2-driven downregulation of the transcription factor Irf6 in breast epithelial cells is required for their 3D growth., PMID:30545388
Novel heterozygous pathogenic variants in CHUK in a patient with AEC-like phenotype, immune deficiencies and 1q21.1 microdeletion syndrome: a case report., PMID:29523099
Intercellular Genetic Interaction Between Irf6 and Twist1 during Craniofacial Development., PMID:28769044
Molecular immunology profiles of monkeys following xenografting with the islets and heart of α-1,3-galactosyltransferase knockout pigs., PMID:27511303
Gene signatures related to HAI response following influenza A/H1N1 vaccine in older individuals., PMID:27441275
Interferon Regulatory Factor 6 Controls Proliferation of Keratinocytes From Children With Van der Woude Syndrome., PMID:27115562
Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse., PMID:23428850
MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate., PMID:20572854
For research use only. Not for human or drug use.
