Catalog No.
RGK23101
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
H2AXS139P, Histone H2A.X (phospho S139), phospho-Histone H2A.X (Ser139)
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
ELISA, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
C6
Preclinical activity of datopotamab deruxtecan, a novel TROP2 directed antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (TROP2) in ovarian carcinoma., PMID:38981151
Pannexin 1 Modulates Angiogenic Activities of Human Endothelial Colony-Forming Cells Through IGF-1 Mechanism and Is a Marker of Senescence., PMID:37589139
Evidence of telomere attrition and a potential role for DNA damage in systemic sclerosis., PMID:35086525
Investigating the level of DNA double-strand break in human spermatozoa and its relation to semen characteristics and IVF outcome using phospho-histone H2AX antibody as a biomarker., PMID:31393082
Cytochrome c oxidase deficiency, oxidative stress, possible antioxidant therapy and link to nuclear DNA damage., PMID:29396562
Multiparameter cytometric analysis of complex cellular response., PMID:29220555
Interlaboratory evaluation of a multiplexed high information content in vitro genotoxicity assay., PMID:28370322
γH2AX and p53 responses in TK6 cells discriminate promutagens and nongenotoxicants in the presence of rat liver S9., PMID:27364561
Wee1 Kinase Inhibitor AZD1775 Radiosensitizes Hepatocellular Carcinoma Regardless of TP53 Mutational Status Through Induction of Replication Stress., PMID:26975930
Experimental Adaptation of Rotaviruses to Tumor Cell Lines., PMID:26828934
Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach., PMID:26764165
Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma., PMID:25940995
Usefulness of monitoring γ-H2AX and cell cycle arrest in HepG2 cells for estimating genotoxicity using a high-content analysis system., PMID:24980598
SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence., PMID:23201774
Follow-up evaluation of radiation-induced DNA damage in CSF disseminated high-grade glioma using phospho-histone H2AX antibody., PMID:21538957
Induction of cell cycle arrest and DNA damage by the HDAC inhibitor panobinostat (LBH589) and the lipid peroxidation end product 4-hydroxynonenal in prostate cancer cells., PMID:21078383
Static electric fields interfere in the viability of cells exposed to ionising radiation., PMID:19399676
Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes., PMID:15235794
For research use only. Not for human or drug use.
