Catalog No.
RGK25101
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
U1 small nuclear RNA, U1 RNA, U1 spliceosomal RNA, U1 snRNA
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Applications
DB, ELISA, IF
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4
A SmD peptide induces better antibody responses to other proteins within the small nuclear ribonucleoprotein complex than to SmD protein via intermolecular epitope spreading., PMID:17277166
U1 small nuclear ribonucleoprotein immune complexes induce type I interferon in plasmacytoid dendritic cells through TLR7., PMID:16368889
A diepitopic sequential oligopeptide carrier (SOCn) as mimic of the sm autoantigen: synthesis, conformation and biological assays., PMID:11277497
[Detection of anti small nuclear ribonucleoprotein antibody in patients with collagen disease--a comparison of sensitivities of four methods]., PMID:7570209
Purification and characterization of human autoantibodies directed to specific regions on U1RNA; recognition of native U1RNP complexes., PMID:8255767
Pulmonary function in systemic lupus erythematosus is related to distinct clinical, serologic, and nailfold capillary patterns., PMID:1466357
Epitope regions on U1 small nuclear RNA recognized by anti-U1RNA-specific autoantibodies., PMID:1385475
Two sisters producing anti-U1RNP exhibit serological concordance and clinical discordance., PMID:1301988
Changes in levels of antibodies against the 70 kDa and a polypeptides of the U1RNP complex in relation to exacerbations of systemic lupus erythematosus., PMID:1830337
Detection of autoantibodies to ribonucleoproteins by counter-immunoelectropheresis, immunoblotting and RNA-immunoprecipitation: comparison of results., PMID:1693324
Human autoimmune serum antibodies against gag gene p30 retroviral protein also react with a U1-SnRNP 68K comigrant protein., PMID:2960408
For research use only. Not for human or drug use.
