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Research Grade Frexalimab

Catalog #:   DHD85405 Specific References (5) DATASHEET
Host species: Humanized
Isotype: IgG1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHD85405

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

sCD40L, Tumor necrosis factor ligand superfamily member 5, T-cell antigen Gp39, CD40L, TNFSF5, CD154, CD40-L, TNF-related activation protein, CD40 ligand, CD40LG, TRAP

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P29965

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

INX-021, SAR 441344, SAR-441344, SAR441344, CAS: 2515463-86-0

Clone ID

Frexalimab

Data Image
  • SDS-PAGE
    SDS PAGE for Frexalimab
References

The role of microglia in multiple sclerosis: implications for treatment with Bruton's tyrosine kinase inhibitors., PMID:40443664

Frexalimab (SAR441344) as a potential multiautoimmune disorder tackling mAB targeting the CD40-CD40L pathway undergoing clinical trials: a review., PMID:39649860

Moving from Insulin Substitution to the Treatment of the Underlying Autoimmune Disease in Type 1 Diabetes., PMID:38688258

Inhibition of CD40L with Frexalimab in Multiple Sclerosis., PMID:38354138

Anti-CD40L antibody frexalimab slows new brain lesions in multiple sclerosis., PMID:37407835

Datasheet

Document Download

Research Grade Frexalimab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Frexalimab [DHD85405]
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