Catalog No.
FHJ77510
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Conjugation
Unconjugated
Target
Signaling lymphocytic activation molecule 5, Hly9-beta, Cell surface antigen MAX.3, Leukocyte differentiation antigen CD84, CD84, SLAM family member 5, SLAMF5
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UIB8
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA0037
Targeting CD84 protein on myeloid-derived suppressor cells as a novel immunotherapy in solid tumors., PMID:39847992
Depletion of myeloid-derived suppressor cells sensitizes murine multiple myeloma to PD-1 checkpoint inhibitors., PMID:39755583
CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer., PMID:39466774
In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis., PMID:39110779
Impact of Functional Polymorphisms on Drug Survival of Biological Therapies in Patients with Moderate-to-Severe Psoriasis., PMID:37240048
NanoString technology distinguishes anti-TIF-1γ+ from anti-Mi-2+ dermatomyositis patients., PMID:34043263
A New Hope for CD56negCD16pos NK Cells as Unconventional Cytotoxic Mediators: An Adaptation to Chronic Diseases., PMID:32373555
Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity., PMID:29337666
Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment., PMID:29164976
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis., PMID:28150777
Slamf6 negatively regulates autoimmunity., PMID:27368806
Polymorphisms in CD84, IL12B and TNFAIP3 are associated with response to biologics in patients with psoriasis., PMID:27564082
Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia., PMID:24289109
Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis., PMID:23555300
[Some considerations of immune metabolism at preeclampsia]., PMID:22306495
Susceptibility loci for the defective foreign protein-induced tolerance in New Zealand Black mice: implication of epistatic effects of Fcgr2b and Slam family genes., PMID:21604261
New targets of pemphigus vulgaris antibodies identified by protein array technology., PMID:21255096
Expression of SLAM (CD150) cell-surface receptors on human B-cell subsets: from pro-B to plasma cells., PMID:20933013
Analysis of HLDA9 mAbs on plasmacytoid dendritic cells., PMID:20933012
Differential expression of SLAMS and other modulatory molecules by human plasma cells during normal maturation., PMID:20923684
Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages., PMID:20628063
The leukocyte receptor CD84 inhibits Fc epsilon RI-mediated signaling through homophilic interaction in transfected RBL-2H3 cells., PMID:18243321
Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules., PMID:17201683
Extensive flow cytometric characterization of plasmacytoid dendritic cell leukemia cells., PMID:16146542
Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling., PMID:16037392
Molecular and cellular pathogenesis of X-linked lymphoproliferative disease., PMID:15661030
2B4 (CD244) is expressed and functional on human eosinophils., PMID:15611233
Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)., PMID:15245368
Homophilic interaction of NTBA, a member of the CD2 molecular family: induction of cytotoxicity and cytokine release in human NK cells., PMID:15162436
Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation., PMID:12928397
Mouse novel Ly9: a new member of the expanding CD150 (SLAM) family of leukocyte cell-surface receptors., PMID:12242590
CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2., PMID:12115647
Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family., PMID:11862385
Structural basis for the interaction of the free SH2 domain EAT-2 with SLAM receptors in hematopoietic cells., PMID:11689425
CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1., PMID:11564780
Activation of lymphocytes inhibits human monocyte to macrophage differentiation., PMID:11563672
CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells., PMID:11486275
Distinct interactions of the X-linked lymphoproliferative syndrome gene product SAP with cytoplasmic domains of members of the CD2 receptor family., PMID:11414741
Genetic approach to insight into the immunobiology of human dendritic cells and identification of CD84-H1, a novel CD84 homologue., PMID:11300479
The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo., PMID:11238035
CD84., PMID:11215822
2B4-mediated activation of human natural killer cells., PMID:11163399
Gene structure of the mouse leukocyte cell surface molecule Ly9., PMID:10970093
The CD2-subset of the Ig superfamily of cell surface molecules: receptor-ligand pairs expressed by NK cells and other immune cells., PMID:10764623
Characterization of MAX.3 antigen, a glycoprotein expressed on mature macrophages, dendritic cells and blood platelets: identity with CD84., PMID:10698700
2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism., PMID:10658976
Molecular cloning and biological characterization of NK cell activation-inducing ligand, a counterstructure for CD48., PMID:10556801
Gene structure of the murine NK cell receptor 2B4: presence of two alternatively spliced isoforms with distinct cytoplasmic domains., PMID:10458751
Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4., PMID:10458320
Phenotypic characterization of human skin mast cells by combined staining with toluidine blue and CD antibodies., PMID:9764855
For research use only. Not for human or drug use.
