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Anti-Human CD303/CLEC4C Antibody (122A2)

Catalog #:   FHJ29010 Specific References (32) DATASHEET
Host species: Mouse
Isotype: IgG1, kappa
Applications: FCM
Accession: Q8WTT0
Overview

Catalog No.

FHJ29010

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

CLEC4C, C-type lectin superfamily member 7, CLECSF11, C-type lectin domain family 4 member C, Dendritic lectin, CD303, DLEC, HECL, Blood dendritic cell antigen 2, BDCA-2, BDCA2, CLECSF7

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8WTT0

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

122A2

Data Image
References

Immunotherapies Targeting CD123 and CD303: A New Frontier in Treating Blastic Plasmacytoid Dendritic Cell Neoplasm., PMID:40141368

Blastic Plasmacytoid Dendritic Cell Neoplasm., PMID:37156483

CD303 (BDCA-2) - a potential novel target for therapy in hematologic malignancies., PMID:34486917

[Myopathy associated with anti-signal recognition peptide antibodies: Five case reports]., PMID:31969510

Blastic Plasmacytoid Dendritic Cell Neoplasm: State of the Art and Prospects., PMID:31035408

Plasmacytoid dendritic cells respond to Epstein-Barr virus infection with a distinct type I interferon subtype profile., PMID:30952679

Improved in vitro and in vivo activity against CD303-expressing targets of the chimeric 122A2 antibody selected for specific glycosylation pattern., PMID:29553870

The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells., PMID:29535732

Detection of Minimal Bone Marrow involvement of Blastic Plasmacytoid Dendritic Cell Neoplastic Cells - CD303 immunostaining as a diagnostic tool., PMID:29415975

Dendritic cells in renal biopsies of patients with acute tubulointerstitial nephritis., PMID:27085555

[Expression of retinoic acid-I nducible gene I in the muscle tissues of idiopathic inflammatory myopathies]., PMID:26712399

Profiling of primary peripheral blood- and monocyte-derived dendritic cells using monoclonal antibodies from the HLDA10 Workshop in Wollongong, Australia., PMID:26682057

A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2., PMID:25995448

The use of wavelength modulated Raman spectroscopy in label-free identification of T lymphocyte subsets, natural killer cells and dendritic cells., PMID:25992777

Transient decrease in human peripheral blood myeloid dendritic cells following influenza vaccination correlates with induction of serum antibody., PMID:24999737

Plasmacytoid dendritic cells in cutaneous lesions of patients with chromoblastomycosis, lacaziosis, and paracoccidioidomycosis: a comparative analysis., PMID:24782102

Peripheral and endometrial dendritic cell populations during the normal cycle and in the presence of endometriosis., PMID:29354600

Optimized immunohistochemical panel to differentiate myeloid sarcoma from blastic plasmacytoid dendritic cell neoplasm., PMID:24390220

The proportion of lymphocytic inflammation with CD123-positive cells in lupus erythematous profundus predict a clinical response to treatment., PMID:24352508

The expression of B7-H1 and B7-H4 co-stimulatory molecules on myeloid and plasmacytoid dendritic cells in pre-eclampsia and normal pregnancy., PMID:23773232

Plasmacytoid dendritic cells in the duodenum of individuals diagnosed with myalgic encephalomyelitis are uniquely immunoreactive to antibodies to human endogenous retroviral proteins., PMID:23422476

Distribution and maturation of skin dendritic cell subsets in two forms of cutaneous T-cell lymphoma: mycosis fungoides and Sézary syndrome., PMID:22678564

Screening of the HLDA9 panel on peripheral blood dendritic cell populations., PMID:20970455

Clinical and immunomodulatory effects of bevacizumab and low-dose interleukin-2 in patients with metastatic renal cell carcinoma: results from a phase II trial., PMID:20840548

BDCA-2 signaling inhibits TLR-9-agonist-induced plasmacytoid dendritic cell activation and antigen presentation., PMID:20673884

Sublingual grass pollen immunotherapy is associated with increases in sublingual Foxp3-expressing cells and elevated allergen-specific immunoglobulin G4, immunoglobulin A and serum inhibitory activity for immunoglobulin E-facilitated allergen binding to B cells., PMID:20184605

Novel role of plasmacytoid dendritic cells in humans: induction of interleukin-10-producing Treg cells by plasmacytoid dendritic cells in patients with rheumatoid arthritis responding to therapy., PMID:20039433

Ratio of myeloid and plasmacytoid dendritic cells and TH2 skew in CRS with nasal polyps., PMID:19793060

Expression of blood dendritic cell antigens (BDCAs) by CD1a+ human pulmonary cells., PMID:19328670

Dendritic cells in renal biopsies of patients with ANCA-associated vasculitis., PMID:19193740

Histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease): lesional cells exhibit an immature dendritic cell phenotype., PMID:19141377

Measurement of CD83 mRNA by real-time polymerase chain reaction to determine removal of dendritic cells by leucoreduction of whole blood., PMID:17561858

Datasheet
$ 225
Product specifications
50 μg 225 100 μg 372

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For research use only. Not for human or drug use.

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Anti-Human CD303/CLEC4C Antibody (122A2) [FHJ29010]
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