Catalog No.
FHD96710
Species reactivity
Human
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
p64, Interleukin-2 receptor subunit gamma, gammaC, IL-2 receptor subunit gamma, CD132, IL-2R subunit gamma, IL-2RG, IL2RG, Cytokine receptor common subunit gamma, Interleukin-4 receptor subunit alpha, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha, IL-4RA, CD124, Soluble interleukin-4 receptor subunit alpha, Soluble IL-4 receptor subunit alpha, Soluble IL-4R-alpha, sIL4Ralpha/prot, IL-4-binding protein, IL4-BP, IL4R, IL4RA, 582J2.1, IL4 receptor complex
Concentration
0.15 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P31785 & P24394
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
A2
Cutaneous T Cell Lymphoma Following Dupilumab Therapy in Patients with Atopic Dermatitis: Clinical Review and Recommendations., PMID:40418285
Dupilumab-associated lymphoproliferative disorders: a comprehensive review on clinicohistopathologic features and underlying mechanisms., PMID:40349527
Dupilumab-Induced Psoriasis in a Patient With Prurigo Nodularis: A Case Report., PMID:40322378
Ocular Side Effects of Dupilumab: A Comprehensive Overview of the Literature., PMID:40217936
Humanized FcεRI Expressed on Mouse Eosinophils Mediates IgE-Facilitated Eosinophil Antigen Presentation., PMID:39996772
Emerging biological treatments for asthma., PMID:39873193
Real-World Evaluation of Dupilumab in the Long-Term Management of Eosinophilic Chronic Rhinosinusitis with Nasal Polyps: A Focus on IL-4 and IL-13 Receptor Blockade., PMID:39768876
Changing paradigms in asthma management., PMID:39709041
Efficacy and safety of anti-CD19 CAR-T in a mouse model of IgG4-related disease., PMID:39672025
Therapies for Chronic Spontaneous Urticaria: Present and Future Developments., PMID:39598410
Interleukin 9 mediates T follicular helper cell activation to promote antibody responses., PMID:39403384
IL-4 promotes chondrogenesis of bone marrow mesenchymal stem cells and blockade of IL-4Rα retards the endochondral ossification during rat embryonic bone development., PMID:39396908
Rapid identification of primary atopic disorders (PAD) by a clinical landmark-guided, upfront use of genomic sequencing., PMID:39381601
Development of a novel humanized anti-TSLP monoclonal antibody, QX008N, and exploration of combination therapy of anti-TSLP antibody and anti-IL-4R antibody., PMID:39276452
Improving Vaccine Response through Probiotics and Micronutrient Supplementation: Evaluating the Role of TLR5 in Adult Female BALB/c Mice., PMID:39257145
Genetic, Clinical, Epidemiological, and Immunological Profiling of IgG Response Duration after SARS-CoV-2 Infection., PMID:39201427
STAT4 and STAT6, their role in cellular and humoral immunity and in diverse human diseases., PMID:39188021
Pharmacological Trends in the Management of Atopic Dermatitis: A Comprehensive Review., PMID:39130865
Escherichia coli LTB26 mutant enhances immune responses to rotavirus antigen VP8 in a mouse model., PMID:39004021
A novel inhalable nanobody targeting IL-4Rα for the treatment of asthma., PMID:38871183
Safe plant Hsp90 adjuvants elicit an effective immune response against SARS-CoV2-derived RBD antigen., PMID:38631949
An alkali-extracted neutral heteropolysaccharide from Phellinus nigricans used as an immunopotentiator in immunosuppressed mice by activating macrophages., PMID:38616084
Is generative pre-trained transformer artificial intelligence (Chat-GPT) a reliable tool for guidelines synthesis? A preliminary evaluation for biologic CRSwNP therapy., PMID:38329526
Regulation of mast cells by overlapping but distinct protein interactions of Siglec-6 and Siglec-8., PMID:38186079
Biomarkers in the Pathogenesis, Diagnosis, and Treatment of Systemic Sclerosis., PMID:37868834
Safety, Pharmacokinetics and Preliminary Efficacy of IL4-Rα Monoclonal Antibody AK120 in Both Healthy and Atopic Dermatitis Subjects: A Phase I, Randomized, Two-Part, Double-Blind, Placebo-Controlled, Dose-Escalation, First-In-Human Clinical Study., PMID:37668898
Anti-interleukin 4 receptor α antibody for the treatment of Chinese bullous pemphigoid patients with diverse comorbidities and a 1-year follow-up: a monocentric real-world study., PMID:37545503
Identification and characterisation of anti-IL-13 inhibitory single domain antibodies provides new insights into receptor selectivity and attractive opportunities for drug discovery., PMID:37483614
Eblasakimab, a novel IL-13 receptor alpha 1 monoclonal antibody, blocks STAT6 phosphorylation with low dose in human volunteers., PMID:37315681
Morphea after initiation of dupilumab in two pediatric atopic dermatitis patients., PMID:37212737
A COVID-19 vaccine candidate based on SARS-CoV-2 spike protein and immune-stimulating complexes., PMID:37093307
Emerging Systemic Treatments for Atopic Dermatitis., PMID:37072648
Dermatophagoides farinae Extract Induces Interleukin 33-Mediated Atopic Skin Inflammation via Activation of RIP1., PMID:36982304
IL-4Rα signalling in B cells and T cells play differential roles in acute and chronic atopic dermatitis., PMID:36599893
Autologous Th2-polarized lymphocytes induce atopic dermatitis lesions in non-atopic human skin xenotransplants., PMID:36597714
Unravelling soluble immune checkpoints in chronic lymphocytic leukemia: Physiological immunomodulators or immune dysfunction., PMID:36248816
Bifidobacterium animalis KV9 and Lactobacillus vaginalis FN3 alleviated β-lactoglobulin-induced allergy by modulating dendritic cells in mice., PMID:36238281
The new indications for biologicals in type 2 diseases: perspectives., PMID:36165457
Critical Players and Therapeutic Targets in Chronic Itch., PMID:36077340
Chemical composition and adjuvant properties of the macromolecules from cultivated Cistanche deserticola Y. C. Ma as an immunopotentiator., PMID:35973483
Biological Therapy of Severe Asthma with Dupilumab, a Dual Receptor Antagonist of Interleukins 4 and 13., PMID:35746582
Novel Biological Therapies for Severe Asthma Endotypes., PMID:35625801
Exploring the efficacy and contribution of Dupilumab in asthma management., PMID:35397375
Interleukins 4 and 13 in Asthma: Key Pathophysiologic Cytokines and Druggable Molecular Targets., PMID:35350765
Multidisciplinary management of type 2 inflammatory diseases., PMID:35127078
Possible role of arginase 1 positive microglia on depressive/anxiety-like behaviors in atopic dermatitis mouse model., PMID:35060088
Combinatorial in silico and in vivo evaluation of immune response elicitation by the affibody ZHER2., PMID:34857479
Signal Integration by Translocation and Phosphorylation of PKCδ in the B Cell Alternate Pathway., PMID:34588218
A new era has begun: Treatment of atopic dermatitis with biologics., PMID:34532635
Molecular Targets for Biological Therapies of Severe Asthma: Focus on Benralizumab and Tezepelumab., PMID:34440488
For research use only. Not for human or drug use.
