Anti-Human EPOR Antibody (ABT-007)

Catalog No.

FHD32810

Species reactivity

Human

Host species

Mouse

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

Unconjugated

Target

EPOR, Erythropoietin receptor, EPO-R

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P19235

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

ABT-007

Autoantibodies to Erythropoietin Receptor and Clinical Outcomes in Patients With Type 2 Diabetes and CKD: A Post Hoc Analysis of CREDENCE Trial., PMID:38344715

Isolation and evaluation of erythroid progenitors in the livers of larval, froglet, and adult Xenopus tropicalis., PMID:37421150

EPOR activation attenuates colitis via enhancing LC3B-dependent apoptotic cell clearance., PMID:37204242

High response rates and transition to transplant after novel targeted and cellular therapies in adults with relapsed/refractory acute lymphoblastic leukemia with Philadelphia-like fusions., PMID:36880203

Association between Anti-Erythropoietin Receptor Antibodies and Cardiac Function in Patients on Hemodialysis: A Multicenter Cross-Sectional Study., PMID:36140193

Endoscopic Postoperative Recurrence in Crohn's Disease After Curative Ileocecal Resection with Early Prophylaxis by Anti-TNF, Vedolizumab or Ustekinumab: A Real-World Multicentre European Study., PMID:35895074

Linking erythropoietin to Treg-dependent allograft survival through myeloid cells., PMID:35389892

HMGB1-mediated restriction of EPO signaling contributes to anemia of inflammation., PMID:35040907

The concentration of brain homogenates with the Amicon Ultra Centrifugal filters., PMID:35004217

Extracellular CIRP-Impaired Rab26 Restrains EPOR-Mediated Macrophage Polarization in Acute Lung Injury., PMID:34925338

Erythropoietin promotes abdominal aortic aneurysms in mice through angiogenesis and inflammatory infiltration., PMID:34290056

Erythropoietin Reduces Auto- and Alloantibodies by Inhibiting T Follicular Helper Cell Differentiation., PMID:34261755

Experimental modulation of Interleukin 1 shows its key role in chronic kidney disease progression and anemia., PMID:33737665

Philadelphia chromosome-negative B-cell acute lymphoblastic leukaemia with kinase fusions in Taiwan., PMID:33707599

Development of luspatercept to treat ineffective erythropoiesis., PMID:33687432

Comparison of Circulating Biomarkers in Predicting Diabetic Kidney Disease Progression With Autoantibodies to Erythropoietin Receptor., PMID:33615053

Carbamylated erythropoietin regulates immune responses and promotes long-term kidney allograft survival through activation of PI3K/AKT signaling., PMID:32934199

Role of the erythropoietin receptor in Lung Cancer cells: erythropoietin exhibits angiogenic potential., PMID:32922549

Bone Marrow Endothelial Cells Take Up Blood-Borne Immune Complexes via Fcγ Receptor IIb2 in an Erythropoietin-Dependent Manner., PMID:32907997

Recombinant Erythropoietin Provides Protection against Renal Fibrosis in Adenine-Induced Chronic Kidney Disease., PMID:32184703

Relationship between autoantibodies to erythropoietin receptor and renal outcome in patients with anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:32024392

Relationship between anti-erythropoietin receptor autoantibodies and responsiveness to erythropoiesis-stimulating agents in patients on hemodialysis: a multi-center cross-sectional study., PMID:31502102

The effects of erythropoiesis-stimulating agents on the management of chemotherapy-induced anemia and tumor growth in diffuse large B-cell lymphoma patients., PMID:30973963

Maea expressed by macrophages, but not erythroblasts, maintains postnatal murine bone marrow erythroblastic islands., PMID:30674470

Methylation of the first exon in the erythropoietin receptor gene does not correlate with its mRNA and protein level in cancer cells., PMID:30606107

Therapeutic time window for the effects of erythropoietin on astrogliosis and neurite outgrowth in an in vitro model of spinal cord injury., PMID:29489692

Protective effect of adenovirus-mediated erythropoietin expression on the spiral ganglion neurons in the rat inner ear., PMID:29436578

Clinical and Pathological Significance of Autoantibodies to Erythropoietin Receptor in Type 2 Diabetic Patients With CKD., PMID:29340323

Local blockage of self-sustainable erythropoietin signaling suppresses tumor progression in non-small cell lung cancer., PMID:29137269

Off-tumor targets compromise antiangiogenic drug sensitivity by inducing kidney erythropoietin production., PMID:29078273

Neuroprotective effect of a new variant of Epo nonhematopoietic against oxidative stress., PMID:28987867

[Significance of anti-EPO receptor antibody in immune-related pancytopenia]., PMID:28535627

Recovery from experimental parkinsonism by intrastriatal application of erythropoietin or EPO-releasing neural precursors., PMID:28373075

Neuroprotective effects of erythropoietin against sevoflurane-induced neuronal apoptosis in primary rat cortical neurons involving the EPOR-Erk1/2-Nrf2/Bach1 signal pathway., PMID:28064106

[A Novel Inhibitory Factor of Erythropoietin: Anti-Erythropoietin Receptor Antibody and Its Characteristics]., PMID:30695518

Grafted Neural Precursors Integrate Into Mouse Striatum, Differentiate and Promote Recovery of Function Through Release of Erythropoietin in MPTP-Treated Mice., PMID:27789613

The serum protein profile of early parity which induces protection against breast cancer., PMID:27769065

Effect of alpha lipoic acid on retinal ganglion cell survival in an optic nerve crush model., PMID:27703307

Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo., PMID:27640183

Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro., PMID:27581518

Development of acute lymphoblastic leukemia with IgH-EPOR in a patient with secondary erythrocytosis., PMID:27544511

Far-western blotting as a solution to the non-specificity of the anti-erythropoietin receptor antibody., PMID:27446474

Erythropoietin ameliorates hyperglycemia in type 1-like diabetic rats., PMID:27350742

[Therapeutic effects and related mechanisms of erythropoietin sustained-release gelatin hydrogel microspheres on a murine model of hindlimb ischemia]., PMID:27346267

Detection of erythroblast antibodies in mitogen-stimulated bone marrow cultures from patients with myelodysplastic syndromes., PMID:27232106

Effect of Autoantibodies to Erythropoietin Receptor in Systemic Lupus Erythematosus with Biopsy-proven Lupus Nephritis., PMID:27134248

Targeted erythropoietin selectively stimulates red blood cell expansion in vivo., PMID:27114509

A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors., PMID:27022756

Erythropoietin receptor and tissue factor are coexpressed in human breast cancer cells., PMID:26854437

Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis., PMID:26419263

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Anti-Human EPOR Antibody (ABT-007).pdf