Catalog No.
                        EVV03001
                        
                                            
                                            
                                            Expression system
                        
                        Mammalian Cells                        
                                                
                                            Species
                        
                        Hepatitis B virus                        
                                                
                                            Protein length
                        
                        Met175-Ile400                        
                                                
                                            Predicted molecular weight
                        
                        29.41 kDa                        
                                                
                                            Nature
                        
                        Recombinant                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Endotoxin level
                        
                        Please contact with the lab for this information.                        
                                                
                                            Purity
                        
                        >90% as determined by SDS-PAGE.                        
                                                
                                            
                                            Accession
                        
                        Q9E6S4                        
                                                
                                            
                                            Applications
                        
                        ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress                        
                                                
                                            Form
                        
                        Lyophilized                        
                                                
                                            Storage buffer
                        
                        Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.                        
                                                
                                            Reconstitution
                        
                        Reconstitute in sterile water for a stock solution.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Shipping
                        
                        In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.                        
                                                
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.                        
                                                
                                            
                                            
                                                Alternative Names
                            Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen, S
                            
                                                    
                                            
                                            
                                        
                 
                
                
                                            O-glycosylated HBsAg peptide can induce specific antibody neutralizing HBV infection. PMID: 34582939
                                            Bulevirtide monotherapy for 48 weeks in patients with HDV-related compensated cirrhosis and clinically significant portal hypertension. PMID: 35973578
                                            Skin immunization with third-generation hepatitis B surface antigen using microneedles. PMID: 31466705
                                            Phosphorylation of the Hepatitis B Virus Large Envelope Protein. PMID: 35282608
                                            Characterization of HBV surface antigen isoforms in the natural history and treatment of HBV infection. PMID: 37026760
                                            HBsAg loading on dendritic cells in patients with chronic hepatitis B: expressions of phenotypic molecules. PMID: 16481284
                                            Micropropagation of transgenic lettuce containing HBsAg as a method of mass-scale production of standardised plant material for biofarming purposes. PMID: 27655251
                                            Immunogenicity of parenterally delivered plant-derived small and medium surface antigens of hepatitis B virus. PMID: 26905723
                                            Plant expression, lyophilisation and storage of HBV medium and large surface antigens for a prototype oral vaccine formulation. PMID: 22246107
                                            A sensitive immunoassay for determination of hepatitis B surface antigen and antibody in human serum using capillary electrophoresis with chemiluminescence detection. PMID: 17689153
                                            Role of hepatitis B virus genotype D & its mutants in occult hepatitis B infection. PMID: 24135177
                                            Adsorption and penetration of hepatitis B virus in a nonpermissive cell line. PMID: 8184545
                                            [Use of baculovector for the expression of HBsAg gene in insect cells]. PMID: 2800542
                                            Inhibition of hepatitis B virus assembly with synthetic peptides derived from the viral surface and core antigens. PMID: 12469306
                                            Hepatitis B virus peptide inhibitors: solution structures and interactions with the viral capsid. PMID: 26100394
                                            [The relationship between serum HBV pgRNA and antigen status in patients with chronic hepatitis B after long-term nucleotide analogues treatment]. PMID: 34517458
                                            Transforming growth factor β as a possible independent factor in chronic hepatitis B. PMID: 33871695
                                            Successful treatment of infantile hepatitis B with lamivudine: A case report. PMID: 34002156
                                            A cellular protein which binds hepatitis B virus but not hepatitis B surface antigen. PMID: 10091999
                                            Two distinct segments of the hepatitis B virus surface antigen contribute synergistically to its association with the viral core particles. PMID: 10024452
                                            Analysis of the cytosolic domains of the hepatitis B virus envelope proteins for their function in viral particle assembly and infectivity. PMID: 17020942
                                            Peptides that block hepatitis B virus assembly: analysis by cryomicroscopy, mutagenesis and transfection. PMID: 9843489
                                            Incidence of hepatitis B virus infection in young Chinese blood donors born after mandatory implementation of neonatal hepatitis B vaccination nationwide. PMID: 29624818
                                            Selection of high affinity ligands to hepatitis B core antigen from a phage-displayed cyclic peptide library. PMID: 12436474
                                            Pre-S1 Mutations as Indicated by Serum Pre-S1 Antigen Negative is Associated with an Increased Risk of Hepatocellular Carcinoma in Chronic Hepatitis B Patients. PMID: 37069959
                                            [HBsAg and anti-HBs in thalassemia non-transfused patients (and in their relatives)]. PMID: 728269
                                            Comparison of direct and indirect two-site binding enzyme immunoassay. PMID: 7046998
                                            [HBsAg in the prevention of post-transfusion hepatitis. General notes and data on the incidence in Umbria]. PMID: 593604
                                            [A case of hepatitis B virus carrier complicated with nephrotic syndrome]. PMID: 10998920