Anti-Human C3c Complement Polyclonal Antibody, FITC

Catalog No.

PHD25841

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human C3c (Glu1322-Cys1661).

Conjugation

FITC

Target

C3c, Complement C3c

Purification

Purified by antigen affinity column.

Applications

ELISA, IF, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Production and Functional Verification of 8-Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)-Edited Donor Pigs for Xenotransplantation., PMID:40190036

Glomerular mesangial cells derived complement factor H regulates complement activation, influences cell proliferation, and maintains actin cytoskeleton., PMID:40157080

Claudin-2 enhances human antibody-mediated complement-dependent cytotoxicity of porcine endothelial cells by modulating antibody binding and complement activation., PMID:40040710

Autoimmune screening panel in patients with multiple sclerosis: A Vienna multiple sclerosis database study., PMID:39601436

Bone impairment in atypical hemolytic and uremic syndrome treated by long-term eculizumab., PMID:39422762

Serotype 15C Streptococcus pneumoniae resistant to classical complement deposition and agglutination by polyclonal rabbit anti-capsular 15B sera., PMID:39368131

C3 concentrations can be normal in patients with C3 glomerulopathy secondary to C3 nephritic factor., PMID:38538072

Lower serum AMH concentration is correlated with serum IgG1 decreased in the infertile woman: A real-world retrospective study., PMID:38286181

Insights into the immunological description of cryoglobulins with regard to detection and characterization in Slovenian rheumatological patients., PMID:37993756

Thrombotic microangiopathy in a patient with anti-signal recognition particle antibody-positive immune-mediated necrotizing myopathy., PMID:37828793

Characteristics of Complement Protein Deposition in Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition., PMID:37713183

Treatment of thrombocytopenia and thrombosis in HIT in mice using deglycosylated KKO: a novel therapeutic?, PMID:37196641

Dysregulated biomarkers of innate and adaptive immunity predict infections and disease progression in cirrhosis., PMID:37035457

Magnetic blood purification-based soluble fms-like tyrosine kinase-1 removal in comparison with dextran sulfate apheresis and therapeutic plasma exchange., PMID:36995348

Successful pharmacological intervention at different levels of the complement system in an in vitro complement fixation model for bullous pemphigoid., PMID:36704908

Tacrolimus Induction Therapy for Nephrotic Syndrome Caused by Minimal Mesangial Lupus Nephritis with Lupus Podocytopathy: A Case-Based Review., PMID:36336892

Role of light and immunofluorescence microscopy to differentiate primary and secondary membranous nephropathy., PMID:36308187

Complement activation in Hidradenitis suppurativa: Covert low-grade inflammation or innocent bystander?, PMID:36211440

Cutaneous Vesiculobullous Lesions: A Clinicopathologic Study., PMID:35435824

Low Serum Levels of Complement C3c at Diagnosis Indicate Poor Outcome in Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis., PMID:35257082

Novel approaches beyond standard immunofluorescence for kidney biopsies., PMID:35256574

Lectin and alternative complement pathway activation in cutaneous manifestations of IgA-vasculitis: A new target for therapy?, PMID:35121432

Yi Shen An, a Chinese traditional prescription, ameliorates membranous glomerulonephritis induced by cationic bovine serum albumin in rats., PMID:35001799

Glomerulonephritis Associated with Infective Endocarditis Showing Serological Positivity for PR3-anti-neutrophil Cytoplasmic Antibody and Anti-glomerular Basement Membrane Antibody., PMID:34980793

Proteinuria is accompanied by intratubular complement activation and apical membrane deposition of C3dg and C5b-9 in kidney transplant recipients., PMID:34927448

Characteristics of immune and inflammatory responses among different age groups of pediatric patients with COVID-19 in China., PMID:34341947

The Spectrum of C4d Deposition in Renal Biopsies of Lupus Nephritis Patients., PMID:34276649

Complement Components C3 and C4 Indicate Vasculitis Manifestations to Distinct Renal Compartments in ANCA-Associated Glomerulonephritis., PMID:34205415

Complement mediates binding and procoagulant effects of ultralarge HIT immune complexes., PMID:34189574

Alternative Complement Pathway Is Activated and Associated with Galactose-Deficient IgA1 Antibody in IgA Nephropathy Patients., PMID:34177889

HLA class I depletion by citric acid, and irradiation of apheresis platelets for transfusion of refractory patients., PMID:33580979

Effects of Hericium erinaceus polysaccharide on immunity and apoptosis of the main immune organs in Muscovy duck reovirus-infected ducklings., PMID:33421472

Diagnostic Utility of C4d by Direct Immunofluorescence in Bullous Pemphigoid., PMID:33395046

Ex vivo assays to detect complement activation in complementopathies., PMID:33148511

Association of Glomerular Complement C4c Deposition With the Progression of Diabetic Kidney Disease in Patients With Type 2 Diabetes., PMID:32983156

A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity., PMID:32938727

Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition., PMID:32877502

Atrase B, a novel metalloprotease with anti-complement and anti-coagulant activity, significantly delays discordant cardiac xenograft rejection., PMID:32529740

Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena., PMID:32444405

A rare case report of autoimmune haemolytic anemia in a female child due to a Donath-Landsteiner antibody., PMID:32249165

Complement activation by IgG containing immune complexes regulates the interaction of C1q with its ligands., PMID:31634815

Utility of immunohistochemistry with C3d in C3 glomerulopathy., PMID:31477814

Complement activation products in the circulation and urine of primary membranous nephropathy., PMID:31399080

[Monoclonal gammopathy of renal significance and membranoproliferative glomerulonephritis: a complex relationship with promising therapeutic opportunities]., PMID:31373468

A study of detection and comparison of immunofluorescence on formalin-fixed paraffin-embedded tissue with fresh frozen renal biopsy specimen., PMID:31031371

Autoantibodies Against C3b-Functional Consequences and Disease Relevance., PMID:30761135

Mast Cells Are a Marked Source for Complement C3 Products That Associate with Increased CD11b-Positive Cells in Keratinocyte Skin Carcinomas., PMID:30689427

The relationship of anti-phospholipase A2 receptor antibody and C5a complement with disease activity and short-term outcome in idiopathic membranous nephropathy., PMID:30639075

Polyreactive IgM initiates complement activation by PF4/heparin complexes through the classical pathway., PMID:30309891

Is Early Complement Activation in Renal Transplantation Associated with Later Graft Outcome?, PMID:30286468

Document Download

Anti-Human C3c Complement Polyclonal Antibody, FITC.pdf