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Research Grade Anti-Human TRAC Antibody (T10B9.1A-31)

Catalog #:   DHB96202 Specific References (60) DATASHEET
Host species: Mouse
Isotype: IgG2b, kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHB96202

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b, kappa

Clonality

Monoclonal

Target

T cell receptor alpha chain constant, TRAC, TCRA

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01848

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

MEDI-500, T10B9, T10B9.1A-31

Clone ID

T10B9.1A-31

Data Image
References

T10B9.1A-31 anti-T-cell monoclonal antibody: preclinical studies and clinical treatment of solid organ allograft rejection, PMID: 2479265

Treatment of acute cellular rejection with T10B9.1A-31 or OKT3 in renal allograft recipients, PMID: 1531095

Complement-mediated T-cell depletion of bone marrow: comparison of T10B9.1A-31 and Muromonab-Orthoclone OKT3, PMID: 11953031

Induction immunotherapy in heart transplantation with T10B9.1A-31: a phase I study, PMID: 9322140

T10B9 monoclonal antibody: a short-acting nonstimulating monoclonal antibody that spares gammadelta T-cells and treats and prevents cellular rejection, PMID: 19920935

Treatment of acute rejection with anti-T-cell antigen receptor complex alpha beta (T10B9.1A-31) or anti-CD3 (OKT3) monoclonal antibody: results of a prospective randomized double-blind trial, PMID: 1899152

Combined in vitro and in vivo T lymphocyte depletion for the control of graft-versus-host disease following haploidentical marrow transplant, PMID: 8607177

Increased frequency of TCR gamma delta + T cells in disease-free survivors following T cell-depleted, partially mismatched, related donor bone marrow transplantation for leukemia, PMID: 8938522

Analysis of risk factors for the development of GVHD after T cell-depleted allogeneic BMT: effect of HLA disparity, ABO incompatibility, and method of T-cell depletion, PMID: 11760150

Allogeneic bone marrow transplantation with T cell-depleted partially matched related donors for advanced acute lymphoblastic leukemia in children and adults: a comparative matched cohort study, PMID: 8807094

Blood Gene Expression Profiling and Donor-derived Cell-free DNA to Noninvasively Diagnose Clinical and Subclinical Kidney Transplant Rejection: A Real-life Appraisal Study., PMID:40020163

A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740

Targeting human plasma cells using regulated BCMA CAR T cells eliminates circulating antibodies in humanized mice., PMID:39673129

BCMA/CD47-directed universal CAR-T cells exhibit excellent antitumor activity in multiple myeloma., PMID:38783333

Allogeneic CAR-T cells with of HLA-A/B and TRAC disruption exhibit promising antitumor capacity against B cell malignancies., PMID:38231412

Generation and optimization of off-the-shelf immunotherapeutics targeting TCR-Vβ2+ T cell malignancy., PMID:38225288

[Preparation of a block copolymer-based temperature-responsive affinity chromatography stationary phase for antibody separation and purification]., PMID:38093534

Production of therapeutic levels of human FIX-R338L by engineered B cells using GMP-compatible medium., PMID:37790246

Antibody-based binding domain fused to TCRγ chain facilitates T cell cytotoxicity for potent anti-tumor response., PMID:37349298

Merging microfluidics with luminescence immunoassays for urgent point-of-care diagnostics of COVID-19., PMID:36373139

Phase 1 clinical trial of CRISPR-engineered CAR19 universal T cells for treatment of children with refractory B cell leukemia., PMID:36288281

Current trends in COVID-19 diagnosis and its new variants in physiological fluids: Surface antigens, antibodies, nucleic acids, and RNA sequencing., PMID:36060607

Pembrolizumab outperforms tyrosine kinase inhibitors as adjuvant treatment in patients with high-risk renal cell carcinoma after nephrectomy., PMID:34992006

2021 Updated European Association of Urology Guidelines on the Use of Adjuvant Pembrolizumab for Renal Cell Carcinoma., PMID:34920897

KPNA1 regulates nuclear import of NCOR2 splice variant BQ323636.1 to confer tamoxifen resistance in breast cancer., PMID:34709749

The RXR Agonist MSU42011 Is Effective for the Treatment of Preclinical HER2+ Breast Cancer and Kras-Driven Lung Cancer., PMID:34638488

Point-of-care COVID-19 diagnostics powered by lateral flow assay., PMID:34629572

Paper-based analytical devices for virus detection: Recent strategies for current and future pandemics., PMID:34462612

The potential of electrochemistry for the detection of coronavirus-induced infections., PMID:33518851

COVID-19: A challenge for electrochemical biosensors., PMID:33487783

Conjugating immunoassays to mass spectrometry: Solutions to contemporary challenges in clinical diagnostics., PMID:33046944

Nucleotide resolution profiling of m7G tRNA modification by TRAC-Seq., PMID:31619810

The T cell receptor (TRA) locus in the rabbit (Oryctolagus cuniculus): Genomic features and consequences for invariant T cells., PMID:31355919

An "off-the-shelf" fratricide-resistant CAR-T for the treatment of T cell hematologic malignancies., PMID:29483708

Adjuvant Therapies in Nonmetastatic Renal-Cell Carcinoma: A Review of the Literature., PMID:29449091

BQ323636.1, a Novel Splice Variant to NCOR2, as a Predictor for Tamoxifen-Resistant Breast Cancer., PMID:29420220

Adjuvant Therapy for High Risk Localized Kidney Cancer: Emerging Evidence and Future Clinical Trials., PMID:28479237

Aptasensors for viral diagnostics., PMID:32287539

Growth factor receptor/steroid receptor cross talk in trastuzumab-treated breast cancer., PMID:24469058

TRAV gene expression in PBMCs and TILs in patients with breast cancer analyzed by a DNA melting curve (FQ-PCR) technique for TCR α chain CDR3 spectratyping., PMID:22862170

Parallel differential mobility analysis for electrostatic characterization and manipulation of nanoparticles and viruses., PMID:25892833

Bioactive paper provides a low-cost platform for diagnostics., PMID:32287534

Silencing mediator of retinoic acid and thyroid hormone receptor regulates enhanced activation of signal transducer and activator of transcription 3 by epstein-barr virus-derived epstein-barr nuclear antigen 2., PMID:19571399

Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells., PMID:18487509

Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions., PMID:17578563

The aryl hydrocarbon receptor activates the retinoic acid receptoralpha through SMRT antagonism., PMID:16480812

Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT)., PMID:16219912

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells., PMID:15531890

Differential recruitment of coregulator proteins steroid receptor coactivator-1 and silencing mediator for retinoid and thyroid receptors to the estrogen receptor-estrogen response element by beta-estradiol and 4-hydroxytamoxifen in human breast cancer., PMID:14715875

Genomic structure around joining segments and constant regions of swine T-cell receptor alpha/delta (TRA/TRD) locus., PMID:12871218

Production of TARC and MDC by naive T cells in asthmatic patients., PMID:12645858

Distinct nuclear body components, PML and SMRT, regulate the trans-acting function of HTLV-1 Tax oncoprotein., PMID:12642864

Assembly of the SMRT-histone deacetylase 3 repression complex requires the TCP-1 ring complex., PMID:12502735

Identification of leptin receptors in lung and isolated fetal type II cells., PMID:12091248

Homogenous enzyme immunoassay for cyclosporine in whole blood using the EMIT 2000 cyclosporine specific assay with the COBAS MIRA-plus analyzer., PMID:11793432

SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains., PMID:11304536

SMRT as a T3SF-binding protein., PMID:11295045

Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3., PMID:10944117

Cross reactivity between human erythropoietin antibody and horse erythropoietin., PMID:10832872

Analytical validation of the PRO-Trac II ELISA for the determination of tacrolimus (FK506) in whole blood., PMID:10471647

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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For research use only. Not for human or drug use.

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Research Grade Anti-Human TRAC Antibody (T10B9.1A-31) [DHB96202]
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