Catalog No.
DVV03003
Description
Libivirumab is a human monoclonal antibody directed against the hepatitis B virus. libivirumab had an IC 50 of 35 and 128 ng/ml in the neutralization assays based on ELISA and immunofluorescence assays.
Expression system
Mammalian Cells
Species reactivity
Hepatitis B virus genotype A (HBV-A)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Large envelope protein, L glycoprotein, L-HBsAg, LHB, Large S protein, Large surface protein, Major surface antigen, S
Concentration
2.4 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03142
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
17.1.41, HepeX-B (combination of exbivirumab and libivirumab), CAS: 569658-79-3
Clone ID
Libivirumab
Novel mechanism of antibodies to hepatitis B virus in blocking viral particle release from cells PMID: 20593455
Preclinical evaluation of two human anti-hepatitis B virus (HBV) monoclonal antibodies in the HBV-trimera mouse model and in HBV chronic carrier chimpanzees. PMID: 10960454
A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations; PMID: 32504577
Grading of renal cell carcinoma. PMID: 30565310
Magnetic resonance classification of lumbar intervertebral disc degeneration. PMID: 11568697
The Treatment of Neck Pain-Associated Disorders and Whiplash-Associated Disorders: A Clinical Practice Guideline. PMID: 27836071
Cytologic Criteria for Mast Cell Tumor Grading in Dogs With Evaluation of Clinical Outcome. PMID: 27034386
A proposed grading system for arteriovenous malformations. PMID: 3760956
Variance of Tumor Grade at Radical Prostatectomy With Assessment of Each Tumor Nodule Versus Global Grading. PMID: 34752602
Impact of breast cancer grade discordance on prediction of outcome. PMID: 29999192
Grading diabetic retinopathy from stereoscopic color fundus photographs--an extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group. PMID: 2062513
Measuring grade inflation: a clinical grade discrepancy score. PMID: 24602828
Analysis of Histological Grade in Resected Lung-invasive Adenocarcinoma. PMID: 30842187
[Grading of gynecological tumors : Current aspects]. PMID: 27379622
Imaging Correlates of Adult Glioma Genotypes. PMID: 28723281
Semi-quantitative grading and extended semi-quantitative grading for osteoporotic vertebral deformity: a radiographic image database for education and calibration. PMID: 32355842
Meningeal solitary fibrous tumor/hemangiopericytoma: Emphasizing on STAT 6 immunohistochemistry with a review of literature. PMID: 30233017
Meningiomas: correlation of Ki67 with histological grade. PMID: 21483118
The impact of brain invasion criteria on the incidence and distribution of WHO grade 1, 2, and 3 meningiomas. PMID: 35139206
Diagnostic grading of parotid lesions by conventional ultrasound: a pilot study. PMID: 35113723
Sequential grade evaluation method exploration of Exocarpium Citri Grandis (Huajuhong) decoction pieces based on "network prediction → grading quantization → efficacy validation". PMID: 35231589
Tumor grade heterogeneity in urothelial bladder carcinoma--proposal of a system using combined numbers. PMID: 11676351
Review of existing grading systems for cervical or lumbar disc and facet joint degeneration. PMID: 16172902
Grading infantile cataracts. PMID: 16792736
Revisiting the Management of Pediatric Kidney Transplants, A Multicenter Analysis. PMID: 36454028
WHO classification of meningiomas-A single institutional experience. PMID: 33144180
The histopathology of pediatric celiac disease: order must prevail out of chaos. PMID: 12574840
Real-life clinical impact of a five-tiered classification of pituitary tumors. PMID: 36315463
An improved system for grading and treating tinnitus. PMID: 29191364
Ki-67 immunoexpression and radiological assessment of necrosis improves accuracy of conventional and modified core biopsy systems in predicting the final grade assigned to adult-soft tissue sarcomas. An international collaborative study. PMID: 34329836
Relationship between FIGO grade and AgNOR, S100-positive langerhans cells in endometrial adenocarcinoma. PMID: 10972859
The Morphological Grading and Comparison of Sutural Patency Among Cranial Sutures in Dry Human Skulls. PMID: 28938334
Grade Inflation in Medical Student Radiation Oncology Clerkships: Missed Opportunities for Feedback? PMID: 26104930
Is there a correlation between meatal stenosis severity, lower urinary tract symptoms and uroflowmetry? PMID: 35491305
Assessing the Predictive Validity of Strength of Evidence Grades: A Meta-Epidemiological Study [Internet]. PMID: 26468566
An update of the Gleason grading system. PMID: 20006878
Femoral Neck Stress Fracture: Can MRI Grade Help Predict Return-to-Running Time? PMID: 27261475
Predictive Performance of Prospectively Applied ISUP and Fuhrman Grade in Nonmetastatic Renal Cell Carcinoma. PMID: 35641263
Grading for suction loss in small incision lenticule extraction. PMID: 36044110
A new strategy for grading of Lu'an guapian green tea by combination of differentiated metabolites and hypoglycaemia effect. PMID: 35940769
Correlation of Nuclear Morphometry with Clinicopathologic Parameters in Malignant Breast Aspirates. PMID: 34568216
Utilising an innovative digital software to grade pre-clinical crown preparation exercise. PMID: 27146473
Validation of a classification system to grade fractionation in atrial fibrillation and correlation with automated detection systems. PMID: 19897499
Utility of PHH3 in Evaluation of Mitotic Index in Breast Carcinoma and Impact on Tumor Grade. PMID: 31983165
Noninvasive Glioma Grading with Deep Learning: A Pilot Study. PMID: 35673102
[Follow-up study of fetal cardiac birth defects after prenatal diagnosis and graded counseling]. PMID: 35484660
Development and Validation of an Algorithm for Quality Grading of Pediatric Spirometry: A Quality Improvement Initiative. PMID: 34343027
Microsurgery for intracranial arteriovenous malformation: Long-term outcomes in 445 patients. PMID: 28323878
Correlation of morphological and radiological characteristics of degenerative disc disease in lumbar spine: a cadaveric study. PMID: 33899206
Toward more rational prediction of outcome in patients with high-grade subarachnoid hemorrhage. PMID: 10626932
Clinical and pathological profile of gastric neuroendocrine tumors. PMID: 35900481
Utilization of an Intraoperative Grading Scale in Laparoscopic Cholecystectomy: A Nepalese Perspective. PMID: 33299408
Kinematic analysis of the relationship between the grade of disc degeneration and motion unit of the cervical spine. PMID: 18197105
Effects of quality grade on the chemical, physical and sensory characteristics of Hanwoo (Korean native cattle) beef. PMID: 22062394
Passive bioelectrical properties for assessing high- and low-grade prostate adenocarcinoma. PMID: 21520155
Grading of astrocytomas. A simple and reproducible method. PMID: 3179928
Family Medicine Clerkship Assessment Analysis: Application and Implications. PMID: 34841207
Breast cancer histologic grading using digital microscopy: concordance and outcome association. PMID: 29535212
Pediatric extradural spinal tumors. PMID: 18334840
Proposal of a simple grading system integrating cosmetic and tonometric aspects of prostaglandin-associated periorbitopathy. PMID: 34449456
Architectural Patterns are a Relevant Morphologic Grading System for Clear Cell Renal Cell Carcinoma Prognosis Assessment: Comparisons With WHO/ISUP Grade and Integrated Staging Systems. PMID: 29356723
The WHO classification of 1973 is more suitable than the WHO classification of 2004 for predicting survival in pT1 urothelial bladder cancer. PMID: 20707791
Intratumoral Susceptibility Signals Reflect Biomarker Status in Gliomas. PMID: 31745161
Graft-versus-Host Disease of the Gut: A Histologic Activity Grading System and Validation. PMID: 28533059
Impact of an increase in grading categories and double reporting on the reliability of breast cancer grade. PMID: 17504304
Comparison of MRI graded cartilage and MRI based volume measurement in knee osteoarthritis. PMID: 15243849
Accuracy of grading pancreatic neuroendocrine neoplasms with Ki-67 index in fine-needle aspiration cellblock material. PMID: 30303569
Effectiveness of a modified therapeutic protocol for the management of vernal keratoconjunctivitis based on Bonini's graded clinical severity. PMID: 35791121
Grading of prostate cancer: the impact of including intraductal carcinoma on the overall Grade Group assigned in diagnostic biopsies. PMID: 32358793
Ultrasound grade of hydronephrosis and severity of renal cortical damage on 99m technetium dimercaptosuccinic acid renal scan in infants with unilateral hydronephrosis during followup and after pyeloplasty. PMID: 11956470
Comparison of microsurgery and endovascular treatment on clinical outcome following poor-grade subarachnoid hemorrhage. PMID: 23830590
Clinical grading of relative afferent pupillary defects. PMID: 8328935
A novel grading system for clear cell renal cell carcinoma incorporating tumor necrosis. PMID: 23348209
Hemangioendothelioma of bone: a study of 29 cases. PMID: 7397643
Inferior turbinate classification system, grades 1 to 4: development and validation study. PMID: 25215619
The expression of survivin and Ki-67 in meningiomas: correlation with grade and clinical outcome. PMID: 15072469
A system of radiological criteria for grading and prognosticating temporal lobe contusions. PMID: 31964226
For research use only. Not for human or drug use.
