Anti-HSD11B2 Polyclonal Antibody

Catalog No.

PHF71301

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human HSD11B2 (Gly106-Arg405).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

HSD11B2,11-beta-HSD type II,11-beta-HSD,11-DH2,Short chain dehydrogenase/reductase family 9C member 3,Corticosteroid 11-beta-dehydrogenase isozyme 2,SDR9C3,NAD-dependent 11-beta-hydroxysteroid dehydrogenase,11-beta-hydroxysteroid dehydrogenase type II,11-beta-hydroxysteroid dehydrogenase type 2,11-beta-HSD2,HSD11K,11-HSD type II

Purification

Purified by antigen affinity column.

Accession

P80365

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Microbiota modulates the steroid response to acute immune stress in male mice., PMID:38361932

Utero-placental expression and functional implications of HSD11B1 and HSD11B2 in canine pregnancy†., PMID:36722005

Artificial Neural Network Analysis-Based Immune-Related Signatures of Primary Non-Response to Infliximab in Patients With Ulcerative Colitis., PMID:34992592

Aldosterone-sensitive HSD2 neurons in mice., PMID:30343334

Cortisol Homeostasis in the Epidermis is Influenced by Topical Corticosteroids in Patients with Atopic Dermatitis., PMID:28794569

Glucocorticoid metabolism in the bovine cumulus-oocyte complex matured in vitro., PMID:26519454

Variable expression of 11beta Hydroxysteroid dehydrogenase (11beta-HSD) isoforms in vascular endothelial cells., PMID:18573267

Expression of 11beta-hydroxysteroid dehydrogenase (11betaHSD) proteins in luteinizing human granulosa-lutein cells., PMID:12844344

Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor., PMID:12015312

Clinical relevance of airway 11beta-hydroxysteroid dehydrogenase type II enzyme in asthma., PMID:11934730

In vivo footprinting of the human 11beta-hydroxysteroid dehydrogenase type 2 promoter: evidence for cell-specific regulation by Sp1 and Sp3., PMID:11850421

11beta-hydroxysteroid dehydrogenase type 2 is expressed in the human kidney glomerulus., PMID:11836336

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