Catalog No.
PHD34501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human EIF2AK2 (Ser224-Ile502).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Protein kinase R,PRKR,Eukaryotic translation initiation factor 2-alpha kinase 2,Interferon-induced,double-stranded RNA-activated protein kinase,Protein kinase RNA-activated,EIF2AK2,Tyrosine-protein kinase EIF2AK2,p68 kinase,PKR,P1/eIF-2A protein kinase,Interferon-inducible RNA-dependent protein kinase,eIF-2A protein kinase 2
Purification
Purified by antigen affinity column.
Accession
P19525
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Using the Ratio of Phosphorylated to Non-phosphorylated Forms of Stress Kinase PKR as a Potential Diagnostic Test for ME/CFS., PMID:40372675
Analysis of the relationships between interferon-stimulated genes and anti-SSA/Ro 60 antibodies in primary Sjögren's syndrome patients via multiomics and machine learning methods., PMID:39577221
Genetics and measles, mumps and rubella vaccine response in childhood and adolescence-A systematic review., PMID:38157324
IFN-beta and EIF2AK2 are potential biomarkers for interstitial lung disease in anti-MDA5 positive dermatomyositis., PMID:36912714
Hantaviruses use the endogenous host factor P58IPK to combat the PKR antiviral response., PMID:34653226
An integrated stress response via PKR suppresses HER2+ cancers and improves trastuzumab therapy., PMID:31086176
Visualization of Double-Stranded RNA Colocalizing With Pattern Recognition Receptors in Arenavirus Infected Cells., PMID:30087859
A Systems Vaccinology Approach Reveals Temporal Transcriptomic Changes of Immune Responses to the Yellow Fever 17D Vaccine., PMID:28687661
Imiquimod-induced autophagy is regulated by ER stress-mediated PKR activation in cancer cells., PMID:28601430
Presence of an interferon signature in individuals who are anti-nuclear antibody positive lacking a systemic autoimmune rheumatic disease diagnosis., PMID:28245862
Opposing Roles of Double-Stranded RNA Effector Pathways and Viral Defense Proteins Revealed with CRISPR-Cas9 Knockout Cell Lines and Vaccinia Virus Mutants., PMID:27334583
Insulin treatment promotes tyrosine phosphorylation of PKR and inhibits polyIC induced PKR threonine phosphorylation., PMID:26321373
Binding of the pathogen receptor HSP90AA1 to avibirnavirus VP2 induces autophagy by inactivating the AKT-MTOR pathway., PMID:25714412
Global transcriptional response to ISCOM-Matrix adjuvant at the site of administration and in the draining lymph node early after intramuscular injection in pigs., PMID:22426325
For research use only. Not for human or drug use.
