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Research Grade Racotumomab

Catalog #:   DGK11201 Specific References (56) DATASHEET
Host species: Mouse
Isotype: IgG1-kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DGK11201

Expression system

Mammalian Cells

Species reactivity

General

Host species

Mouse

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Idiotope of anti-(N-glycolylneuraminic acid (NeuGc,NGNA) -gangliosides GM3) Mus musculus IgM-kappa monoclonal antibody P3/chP3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

1E10, CAS: 946832-34-4

Clone ID

Racotumomab

Data Image
  • SDS-PAGE
    SDS PAGE for Racotumomab
References

Racotumomab for treating lung cancer and pediatric refractory malignancies, PMID: 26903265

Racotumomab - a novel anti-idiotype monoclonal antibody vaccine for the treatment of cancer, PMID: 24918647

Racotumomab-alum vaccine for the treatment of non-small-cell lung cancer, PMID: 25420897

Prognostic Significance of Tumor Tissue NeuGcGM3 Ganglioside Expression in Patients Receiving Racotumomab Immunotherapy, PMID: 32670370

Antibody-dependent cell-mediated cytotoxicity induced by active immunotherapy based on racotumomab in non-small cell lung cancer patients, PMID: 29936534

Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides - preclinical and clinical data, PMID: 23110257

Immune response to racotumomab in a child with relapsed neuroblastoma, PMID: 23267436

Preclinical evaluation of racotumomab, an anti-idiotype monoclonal antibody to N-glycolyl-containing gangliosides, with or without chemotherapy in a mouse model of non-small cell lung cancer, PMID: 23162791

A Phase I Study of the Anti-Idiotype Vaccine Racotumomab in Neuroblastoma and Other Pediatric Refractory Malignancies, PMID: 26154941

A randomized, multicenter, placebo-controlled clinical trial of racotumomab-alum vaccine as switch maintenance therapy in advanced non-small cell lung cancer patients, PMID: 24788102

Anti-ganglioside antibodies induced in chickens by an alum-adsorbed anti-idiotype antibody targeting NeuGcGM3, PMID: 23335925

Antibodies to watch in 2015, PMID: 25484055

Cancer vaccine characterization: from bench to clinic, PMID: 24641959

Glycans as targets for therapeutic antitumor antibodies, PMID: 22894669

NGcGM3 ganglioside: a privileged target for cancer vaccines, PMID: 21048926

Which are the antibodies to watch in 2013?, PMID: 23254906

GM3(Neu5Gc) ganglioside: an evolution fixed neoantigen for cancer immunotherapy, PMID: 30318083

Pilot study of a novel combination of two therapeutic vaccines in advanced non-small-cell lung cancer patients, PMID: 24777612

Immunotherapy: is a minor god yet in the pantheon of treatments for lung cancer?, PMID: 25148289

Immunotherapy for lung cancer: ongoing clinical trials, PMID: 24143916

Anti-idiotype antibodies in cancer treatment: the pharmaceutical industry perspective, PMID: 23112955

Single-agent maintenance therapy for advanced non-small cell lung cancer (NSCLC): a systematic review and Bayesian network meta-analysis of 26 randomized controlled trials, PMID: 27781159

Combined therapeutic effect of a monoclonal anti-idiotype tumor vaccine against NeuGc-containing gangliosides with chemotherapy in a breast carcinoma model, PMID: 19377876

Crystal structure of an anti-ganglioside antibody, and modelling of the functional mimicry of its NeuGc-GM3 antigen by an anti-idiotypic antibody, PMID: 19748674

The Rapid Development and Early Success of Covid 19 Vaccines Have Raised Hopes for Accelerating the Cancer Treatment Mechanism, PMID: 33818952

Differential effects of two therapeutic cancer vaccines on short- and long-term survival populations among patients with advanced lung cancer, PMID: 30318084

Treatment of Advanced NSCLC Patients with an Anti-Idiotypic NeuGcGM3-Based Vaccine: Immune Correlates in Long-Term Survivors., PMID:40426949

Therapeutic vaccines for advanced non-small cell lung cancer., PMID:38470132

GD2 Expression in Medulloblastoma and Neuroblastoma for Personalized Immunotherapy: A Matter of Subtype., PMID:36551537

Racotumomab in Non-Small Cell Lung Cancer as Maintenance and Second-Line Treatment., PMID:34516533

The Rapid Development and Early Success of Covid 19 Vaccines Have Raised Hopes for Accelerating the Cancer Treatment Mechanism., PMID:33818952

Prognostic Significance of Tumor Tissue NeuGcGM3 Ganglioside Expression in Patients Receiving Racotumomab Immunotherapy., PMID:32670370

Differential effects of two therapeutic cancer vaccines on short- and long-term survival populations among patients with advanced lung cancer., PMID:30318084

GM3(Neu5Gc) ganglioside: an evolution fixed neoantigen for cancer immunotherapy., PMID:30318083

Antibody-dependent cell-mediated cytotoxicity induced by active immunotherapy based on racotumomab in non-small cell lung cancer patients., PMID:29936534

Single-agent maintenance therapy for advanced non-small cell lung cancer (NSCLC): a systematic review and Bayesian network meta-analysis of 26 randomized controlled trials., PMID:27781159

Racotumomab for treating lung cancer and pediatric refractory malignancies., PMID:26903265

A Phase I Study of the Anti-Idiotype Vaccine Racotumomab in Neuroblastoma and Other Pediatric Refractory Malignancies., PMID:26154941

Antibodies to watch in 2015., PMID:25484055

Racotumomab-alum vaccine for the treatment of non-small-cell lung cancer., PMID:25420897

Immunotherapy: is a minor god yet in the pantheon of treatments for lung cancer?, PMID:25148289

Racotumomab - a novel anti-idiotype monoclonal antibody vaccine for the treatment of cancer., PMID:24918647

A randomized, multicenter, placebo-controlled clinical trial of racotumomab-alum vaccine as switch maintenance therapy in advanced non-small cell lung cancer patients., PMID:24788102

Pilot study of a novel combination of two therapeutic vaccines in advanced non-small-cell lung cancer patients., PMID:24777612

Cancer vaccine characterization: from bench to clinic., PMID:24641959

Immunotherapy for lung cancer: ongoing clinical trials., PMID:24143916

Anti-ganglioside antibodies induced in chickens by an alum-adsorbed anti-idiotype antibody targeting NeuGcGM3., PMID:23335925

Immune response to racotumomab in a child with relapsed neuroblastoma., PMID:23267436

Which are the antibodies to watch in 2013?, PMID:23254906

Preclinical evaluation of racotumomab, an anti-idiotype monoclonal antibody to N-glycolyl-containing gangliosides, with or without chemotherapy in a mouse model of non-small cell lung cancer., PMID:23162791

Anti-idiotype antibodies in cancer treatment: the pharmaceutical industry perspective., PMID:23112955

Racotumomab: an anti-idiotype vaccine related to N-glycolyl-containing gangliosides - preclinical and clinical data., PMID:23110257

Glycans as targets for therapeutic antitumor antibodies., PMID:22894669

NGcGM3 ganglioside: a privileged target for cancer vaccines., PMID:21048926

Crystal structure of an anti-ganglioside antibody, and modelling of the functional mimicry of its NeuGc-GM3 antigen by an anti-idiotypic antibody., PMID:19748674

Combined therapeutic effect of a monoclonal anti-idiotype tumor vaccine against NeuGc-containing gangliosides with chemotherapy in a breast carcinoma model., PMID:19377876

Datasheet

Document Download

Research Grade Racotumomab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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For research use only. Not for human or drug use.

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Research Grade Racotumomab [DGK11201]
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