Catalog No.
YHE44001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln22-Ser302
Predicted molecular weight
33.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43632
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
P58 natural killer cell receptor clones CL-39/CL-17, CD158i, MHC class I NK cell receptor, CD158I, p58 NK receptor CL-39/CL-17, NKAT8, KKA3, NKAT-8, CD158 antigen-like family member I, Killer cell immunoglobulin-like receptor 2DS4, Natural killer-associated transcript 8, KIR2DS4
Association of the Genetic Diversity of Killer Cell Immunoglobulin-like Receptor Genes and HLA-C Ligand in Saudi Women With Thyroid Cancer., PMID:39365900
Genetic complexity of killer-cell immunoglobulin-like receptor genes in human pangenome assemblies., PMID:39251346
Evaluation of the genetic diversity of KIR genes in patients with endometrial cancer., PMID:38387251
HLA-DPB1*13:01 associates with enhanced, and KIR2DS4*001 with diminished protection from developing severe COVID-19., PMID:37850268
KIR2DS4 and Its Variant KIR1D in KIR-AA Genotype Donors Showed Differential Survival Impact in Patients with Lymphoid Disease after HLA-Matched Unrelated Hematopoietic Stem Cell Transplantation., PMID:37150297
[Establishment of sequence-based typing assay for KIR2DS4 gene and identification of a new allele KIR2DS4*016]., PMID:35773759
Dynamic mRNA expression of donor-derived activating KIR genes and their significant effects on clinical outcome after haematopoietic stem cell transplantation., PMID:34085290
Population Difference in Allele Frequency of HLA-C*05 and Its Correlation with COVID-19 Mortality., PMID:33233780
Characterization of Surface Receptor Expression and Cytotoxicity of Human NK Cells and NK Cell Subsets in Overweight and Obese Humans., PMID:33101297
Association of killer-cell immunoglobulin-like receptor genes with acute myelogenous leukaemia., PMID:32767509
The impact of donor full-length KIR2DS4 in the development of acute and chronic GVHD after unrelated allogeneic HSCT., PMID:32594584
Natural killer cell receptor variants and chronic hepatitis B virus infection in the Vietnamese population., PMID:32422377
Positive association of Bx genotype, KIR2L5, KIR2DS5 and full-length KIR2DS4 with the risk of meningioma., PMID:31899050
Activating killer cell immunoglobulin-like receptors: Detection, function and therapeutic use., PMID:31755661
KIR2DS4, KIR2DL2, and KIR2DS4del are linked with basaloid tumors, lymph node metastasis, advanced stage and metastatic risk in head and neck squamous cell carcinoma., PMID:31751561
A natural killer cell receptor takes sharp aim at the world of bacteria., PMID:31175150
Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C., PMID:31138701
Combination of KIR2DS4 and FcγRIIa polymorphisms predicts the response to cetuximab in KRAS mutant metastatic colorectal cancer., PMID:30796344
A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation., PMID:30679439
[Relationship between activation of endometrial CD56+ natural killers and the character of leiomyoma nodules growth in patients with uterine leiomyoma.]., PMID:30672678
Acute Exercise Increases the Expression of KIR2DS4 by Promoter Demethylation in NK Cells., PMID:30508863
Killer-cell immunoglobulin-like receptors associated with polycystic ovary syndrome., PMID:30099219
KIR2DS1, 2DS5, 3DS1 and KIR2DL5 are associated with the risk of head and neck squamous cell carcinoma in Iranians., PMID:29408295
The effect of killer cell immunoglobulin-like receptor genotype on outcome of hematopoietic stem cell transplantation from matched sibling., PMID:28993188
Distribution of KIR genes and KIR2DS4 gene variants in two Mexican Mestizo populations., PMID:28734803
[Genetic polymorphisms of KIR2DS4 gene among ethnic Hans from southern China]., PMID:28186587
The impact of KIR2DS4 gene on clinical outcome after hematopoietic stem cell transplantation., PMID:27998801
KIR 2D (L1, L3, L4, S4) and KIR 3DL1 protein expression in non-small cell lung cancer., PMID:27893413
Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy., PMID:27815424
Identification of a Natural Killer Cell Receptor Allele That Prolongs Survival of Cytomegalovirus-Positive Glioblastoma Patients., PMID:27406829
The early onset of type 1 autoimmune hepatitis has a strong genetic influence: role of HLA and KIR genes., PMID:26890333
KIR2DS4 and Its Variant KIR1D Are Associated with Acute Graft-versus-Host Disease, Cytomegalovirus, and Overall Survival after Sibling-Related HLA-Matched Transplantation in Patients with Donors with KIR Gene Haplotype A., PMID:26476204
[Association of KIR2DS4 and its variant KIR1D with the outcome after HLA- identical sibling hematopoietic stem cell transplantation]., PMID:26462640
Genetic (KIR, HLA-C) and Some Clinical Parameters Influencing the Level of Liver Enzymes and Early Virologic Response in Patients with Chronic Hepatitis C., PMID:26206121
Killer immunoglobulin receptor genes and their HLA-C ligand are associated with Type 1 diabetes in an Eastern Indian population., PMID:26031759
Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles., PMID:25961063
KIR2DS5 in the presence of HLA-C C2 protects against endometriosis., PMID:25724317
The HLA-C*04: 01/KIR2DS4 gene combination and human leukocyte antigen alleles with high population frequency drive rate of HIV disease progression., PMID:25715101
Genetic diversity of the KIR/HLA system and susceptibility to hepatitis C virus-related diseases., PMID:25700262
Novel insights in the genomic organization and hotspots of recombination in the human KIR locus through analysis of intergenic regions., PMID:25503311
Presence of the full-length KIR2DS4 gene reduces the chance of rheumatoid arthritis patients to respond to methotrexate treatment., PMID:25069714
KIR2DS4 promotes HIV-1 pathogenesis: new evidence from analyses of immunogenetic data and natural killer cell function., PMID:24901871
Associations between genes for killer immunoglobulin-like receptors and their ligands in patients with epithelial ovarian cancer., PMID:24755350
Investigation of deletion of 22pb in KIR2DS4 gene in a population of southern Brazil., PMID:24659081
KIR2DS4 allelic variants: Differential effects on in utero and intrapartum HIV-1 mother-to-child transmission., PMID:24239756
Detection and significance of cytotoxic cell subsets in biopsies of HCV-infected human livers., PMID:24232187
A comprehensive analysis of the binding of anti-KIR antibodies to activating KIRs., PMID:24173145
DAP12 impacts trafficking and surface stability of killer immunoglobulin-like receptors on natural killer cells., PMID:23715743
Alterations in NK cell phenotype in relation to liver steatosis in children with chronic hepatitis C., PMID:23558709
Study of the KIR gene profiles and analysis of the phylogenetic relationships of Rajbanshi population of West Bengal, India., PMID:23354323
For research use only. Not for human or drug use.
