Recombinant Human CD158j/KIR2DS2 Protein, N-GST

Catalog No.

YHE43901

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

His22-Glu291

Predicted molecular weight

56.57 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P43631

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

CD158 antigen-like family member J, p58 NK receptor CL-49, NKAT5, CD158J, CD158j, MHC class I NK cell receptor, p58 natural killer cell receptor clone CL-49, NKAT-5, NK receptor 183 ActI, Natural killer-associated transcript 5, KIR2DS2, Killer cell immunoglobulin-like receptor 2DS2

Cutting edge: selective expression of inhibitory or activating killer cell Ig-like receptors in circulating CD4+ T lymphocytes., PMID:18292496

Regulation of gammadelta T cell survival by soluble HLA-I: involvement of CD8 and activating killer Ig-like receptors., PMID:16114098

Expression of MHC class I receptors confers functional intraclonal heterogeneity to a reactive expansion of gammadelta T cells., PMID:15864777

Expression of inhibitory KIR is confined to CD8+ effector T cells and limits their proliferative capacity., PMID:15549734

De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes., PMID:12816883

Crystal structure of the human natural killer cell activating receptor KIR2DS2 (CD158j)., PMID:12668644

Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4+ T cells., PMID:12591902

BCR/ABL alters the function of NK cells and the acquisition of killer immunoglobulin-like receptors (KIRs)., PMID:12511422

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