Catalog No.
YHE24301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu2-Asp175
Predicted molecular weight
22.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P39687
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
pp32, Putative HLA-DR-associated protein I, MAPM, ANP32A, C15orf1, Acidic leucine-rich nuclear phosphoprotein 32 family member A, Mapmodulin, LANP, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, PHAPI, Leucine-rich acidic nuclear protein, Acidic nuclear phosphoprotein pp32, PHAP1
ANP32 proteins from ticks and vertebrates are key host factors for replication of Bourbon virus across species., PMID:40366164
PA and PA-X: two key proteins from segment 3 of the influenza viruses., PMID:40160474
Evolutionary Pro-To-Thr Mutation in the Intrinsically Disordered Domain of ANP32 Family Members Modulates Their Target Binding Modes., PMID:39887951
Human ANP32A/B are SUMOylated and utilized by avian influenza virus NS2 protein to overcome species-specific restriction., PMID:39737943
Chicken ANP32A-independent replication of highly pathogenic avian influenza viruses potentially leads to mammalian adaptation-related amino acid substitutions in viral PB2 and PA proteins., PMID:39570060
Equine ANP32 proteins support influenza A virus RNA polymerase activity., PMID:39491182
Revealing disease subtypes and heterogeneity in common variable immunodeficiency through transcriptomic analysis., PMID:39396099
Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase., PMID:39160148
Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core., PMID:38875296
Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses., PMID:38816392
C/EBPβ: A transcription factor associated with the irreversible progression of Alzheimer's disease., PMID:38644578
The temporal protein signature analyses of developing human deciduous molar tooth germ., PMID:38522031
PB2 residue 473 contributes to the mammalian virulence of H7N9 avian influenza virus by modulating viral polymerase activity via ANP32A., PMID:38421166
H3K4 Trimethylation Mediate Hyperhomocysteinemia Induced Neurodegeneration via Suppressing Histone Acetylation by ANP32A., PMID:38351418
Hepatitis B virus RNAs co-opt ELAVL1 for stabilization and CRM1-dependent nuclear export., PMID:38306394
Avian ANP32A incorporated in avian influenza A virions promotes interspecies transmission by priming early viral replication in mammals., PMID:38295177
An Influenza A virus can evolve to use human ANP32E through altering polymerase dimerization., PMID:37816726
Creating resistance to avian influenza infection through genome editing of the ANP32 gene family., PMID:37816720
ANP32A Knockdown Attenuates the Malignant Biological Behavior of Colorectal Cancer Cells by Suppressing Epithelial-mesenchymal Transition and ERK Activation., PMID:37781083
Comparative analysis of PB2 residue 627E/K/V in H5 subtypes of avian influenza viruses isolated from birds and mammals., PMID:37720472
Multivalent Dynamic Colocalization of Avian Influenza Polymerase and Nucleoprotein by Intrinsically Disordered ANP32A Reveals the Molecular Basis of Human Adaptation., PMID:37707433
Glaucoma-Associated CDR1 Peptide Promotes RGC Survival in Retinal Explants through Molecular Interaction with Acidic Leucine Rich Nuclear Phosphoprotein 32A (ANP32A)., PMID:37509196
The SUMO-interacting motif in NS2 promotes adaptation of avian influenza virus to mammals., PMID:37436988
Mammalian ANP32A and ANP32B Proteins Drive Differential Polymerase Adaptations in Avian Influenza Virus., PMID:37074204
[Silenced ANP32A inhibits the growth, invasion and migration of colorectal cancer in vitro via the inactivation of AKT pathway]., PMID:36856210
Avian Influenza A Virus Polymerase Can Utilize Human ANP32 Proteins To Support cRNA but Not vRNA Synthesis., PMID:36645303
Time- and Concentration-Dependent Stimulation of Oxidative Stress in Chondrocytes by Intracellular Soluble Urate., PMID:36578257
Anp32a Promotes Neuronal Regeneration after Spinal Cord Injury of Zebrafish Embryos., PMID:36555564
Characteristic gene prognostic model of type 1 diabetes mellitus via machine learning strategy., PMID:36477008
Hypoxia and Wnt signaling inversely regulate expression of chondroprotective molecule ANP32A in articular cartilage., PMID:36370958
Application of Feature Selection and Deep Learning for Cancer Prediction Using DNA Methylation Markers., PMID:36140725
AIMP1 promotes multiple myeloma malignancy through interacting with ANP32A to mediate histone H3 acetylation., PMID:36042007
[Purification of influenza C virus polymerase based on huANP32A protein and efficient preparation of monoclonal antibody targeting PB2 protein]., PMID:36002430
Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration., PMID:35713529
Sevoflurane inhibits histone acetylation and contributes to cognitive dysfunction by enhancing the expression of ANP32A in aging mice., PMID:35659510
Blood mRNA Expression in Alzheimer's Disease and Dementia With Lewy Bodies., PMID:35283023
ANP32 Family as Diagnostic, Prognostic, and Therapeutic Biomarker Related to Immune Infiltrates in Hepatocellular Carcinoma., PMID:35280441
ANP32A represses Wnt signaling across tissues thereby protecting against osteoarthritis and heart disease., PMID:35227892
KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity., PMID:35044222
The Host Factor ANP32A Is Required for Influenza A Virus vRNA and cRNA Synthesis., PMID:34935435
Mechanistic Insight Into the Regulation of Immune-Related Genes Expression in Autism Spectrum Disorder., PMID:34746237
Anti-ANP32A antibodies in systemic sclerosis., PMID:34697026
Small peptide targeting ANP32A as a novel strategy for acute myeloid leukemia therapy., PMID:34678588
A natural variant in ANP32B impairs influenza virus replication in human cells., PMID:34524075
DAXX represents a new type of protein-folding enabler., PMID:34408321
Asp149 and Asp152 in chicken and human ANP32A play an essential role in the interaction with influenza viral polymerase., PMID:33982347
Multitarget neuroprotection by quercetin: Changes in gene expression in two perinatal asphyxia models., PMID:33951501
Inhibition of the PP2A activity by the histone chaperone ANP32B is long-range allosterically regulated by respiratory cytochrome c., PMID:33882408
Behavioral sensitization induced by methamphetamine causes differential alterations in gene expression and histone acetylation of the prefrontal cortex in rats., PMID:33823794
The mammalian Hedgehog pathway is modulated by ANP32 proteins., PMID:33761414
For research use only. Not for human or drug use.
