Catalog No.
YHD14801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln21-Pro220
Predicted molecular weight
24.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P16070
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hyaluronate receptor, MDU2, HUTCH-I, MDU3, Phagocytic glycoprotein I, CDw44, Epican, Phagocytic glycoprotein 1, ECMR-III, CD44, Hermes antigen, PGP-1, PGP-I, GP90 lymphocyte homing/adhesion receptor, LHR, CD44 antigen, MIC4, Extracellular matrix receptor III, Heparan sulfate proteoglycan
Preparation and antitumor of hyaluronic acid-human serum albumin-indocyanine green-paclitaxel nanoparticles., PMID:40513730
Upholding hyaluronic acid's multi-functionality for nucleic acid drug delivery to target EMT in breast cancer., PMID:40512590
Fenbendazole Exhibits Antitumor Activity Against Cervical Cancer Through Dual Targeting of Cancer Cells and Cancer Stem Cells: Evidence from In Vitro and In Vivo Models., PMID:40509264
Hyaluronan: An Architect and Integrator for Cancer and Neural Diseases., PMID:40507943
Anti-Tumor Activities of Anti-Siglec-15 Chimeric Heavy-Chain Antibodies., PMID:40507880
Targeted suppression of SPP1 inhibits tumor invasion and metastasis in NRF2 hyperactivated cisplatin resistant HNSCC., PMID:40501947
Matrix Stiffness Promotes Invasion and Metastasis of Hepatocellular Carcinoma via a New Mechanoresponsive SCD1/HMMR Pathway., PMID:40497374
Unveiling immune and signalling proteins in recurrent pregnancy loss: GEO2R analysis sheds light., PMID:40494171
Iridium Oxide Nanoparticle-Decorated Metal-Organic Framework: A Synergistic Platform for Photodynamic and Photothermal Cancer Therapy., PMID:40492358
CD44 Deficiency Induces Combinatory NRF2 Inhibition and Endoplasmic Reticulum Stress-Associated Dyserythropoiesis., PMID:40488748
Erianin inhibits the proliferation and stemness of pancreatic cancer cells by interacting with MEK1/2., PMID:40484042
CD44-downregulation in multiple myeloma inhibits cytoskeleton rearrangement through actin depolymerization., PMID:40481899
Tenogenic potential of tendon-derived mesenchymal stem cells isolated post-mortem: Impact of cryopreservation., PMID:40472780
Hyaluronic acid-engineered milk extracellular vesicles to target triple negative breast cancer through CD44., PMID:40468893
Crosstalk of injured podocytes with parietal epithelial cells through Wnt4/β-Catenin signaling., PMID:40467671
Innovative design of hyaluronic acid conjugated polymeric drug for targeted therapy of non-small cell lung cancer., PMID:40466829
The Regulatory Effect of Human Umbilical Cord Mesenchymal Stem Cells on the Gut Microbiota in Diabetic Nephropathy Rats., PMID:40463945
[Mechanism of matrine against senescence in human umbilical vein endothelial cells based on network pharmacology and experimental verification]., PMID:40461235
Sialylated IgG expressed in triple-negative breast cancer cells promotes cancer progression by promoting glycolysis., PMID:40457370
In silico prediction of differentially expressed genes and functionally grouped networks in patients with inflamed pulp for screening pulpitis biomarkers., PMID:40453410
Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay., PMID:40448637
The interaction of the biocompatible scaffold containing nanochitosan-chitosan-polycaprolactone with telomerase activator and rock inhibitor in propagation and functional properties of corneal endothelial cells., PMID:40446990
Targeting SPP1+ macrophages via the SPP1-CD44 axis reveals a key mechanism of immune suppression and tumor progression in ovarian cancer., PMID:40446696
Ovalbumin-specific regulatory T cells differentiated from the naïve phenotype (CD44loCD62Lhi) in mesenteric lymph nodes stably suppress enteropathy even in severe food-allergic mice., PMID:40446078
MIF regulates T helper 17 cell differentiation by activating the p38 MAPK signaling pathway to drive the pathogenesis of EAP., PMID:40440956
Alterations in gene expression associated with invasion of RAS-mutant thyroid tumors and their potential diagnostic and therapeutic utility., PMID:40440326
TNF-Stimulated Gene-6, Part of Extracellular Vesicles in Adipose Tissue-Derived Mesenchymal Stem Cell Concentrated Conditioned Medium, Affects Microglial Activity., PMID:40439794
Evaluation of the Interaction Between Wharton's Jelly-Derived Mesenchymal Stem Cells and β-Mercaptoethanol., PMID:40438831
CD44 knockdown alters miRNA expression and their target genes in colon cancer., PMID:40438109
CD44-targeted RIP3 gene delivery strategy for enhanced cancer therapy via necroptosis and immune modulation., PMID:40436345
Engineering Mechanical Microenvironments: Integration of Substrate and Flow Mechanics Reveals the Impact on the Endothelial Glycocalyx., PMID:40434411
CD44 Marks Dormant Tumor Cells After HER2 Inhibition in Breast Cancer Cells., PMID:40430044
The TIP60-CD44 Axis Modulates Colorectal Cancer Stemness., PMID:40422189
Innovating Glioma Therapy Using Secretions from Umbilical Cord Mesenchymal Stem Cells to Target Homeobox and Growth Factor Genes., PMID:40421391
Targeting of the IL-33/Wnt axis restricts breast cancer stemness and metastasis., PMID:40414980
Zebrafish CD44a variants suppress antiviral immunity through regulation of RIG-I ubiquitination and degradation., PMID:40412572
Synovium-on-a-Chip Reveals Fibroblast-Macrophage Crosstalk Underpinning Joint Homeostasis and Evaluation of Gout Therapies., PMID:40411870
The glycocalyx: a key target for treatment of severe acute pancreatitis-associated multiple organ dysfunction syndrome., PMID:40411704
The transcriptional regulator Sin3a activates CD44 and promotes collective luminal breast cancer cell migration., PMID:40409554
Paricalcitol plus hydroxychloroquine enhances gemcitabine activity and induces mesenchymal to epithelial transition in pancreatic ductal adenocarcinoma: A single cell RNA-seq analysis., PMID:40409452
Single-cell RNA sequencing reveals adrb1 as a sympathetic nerve-regulated immune checkpoint driving T cell exhaustion and impacting immunotherapy in esophageal squamous cell carcinoma., PMID:40406147
Tumor-targeting and redox-responsive photo-cross-linked nanogel derived from multifunctional hyaluronic acid-lipoic acid conjugates for enhanced in vivo protein delivery., PMID:40403518
CD44 and αV-integrins dual-targeting bimetallic nanozymes for lung adenocarcinoma therapy via NIR-enhanced ferroptosis/apoptosis., PMID:40403445
Effect of human survivin-2B-specific cytotoxic CD8+ T lymphocytes on CD44+/- HSC-2 and HSC-3 oral cancer cells., PMID:40399621
A proteotranscriptomic approach to dissect the molecular landscape of human retinoblastoma., PMID:40395327
Establishment and characterization of patient-derived tongue squamous cell carcinoma cell lines., PMID:40394426
Hyaluronan-decorated-phloroglucinol-loaded mesoporous silica nanoparticles downregulate GLI1 and SMO genes of hedgehog signaling pathway in gastrointestinal cancer stem-like cells., PMID:40393597
Immunoprofile of some surface and cytoplasmic peripheral cell adhesion molecules in oral squamous cell carcinoma., PMID:40384204
CD44 is a macrophage receptor for TcdB from Clostridioides difficile that via its lysine-158 succinylation contributes to inflammation., PMID:40383912
Triple synergistic cancer targeting strategies utilizing redox-sensitive fattigated hyaluronic acid nanoparticles encapsulating doxorubicin., PMID:40379189