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Research Grade Clervonafusp Alfa

Catalog #:   DHC80002 Specific References (100) DATASHEET
Host species: Humanized
Isotype: IgG1
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DHC80002

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1

Clonality

Monoclonal

Target

Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, 36 kDa nucleolar protein HNP36, ENT2, Equilibrative nucleoside transporter 2, SLC29A2, Hydrophobic nucleolar protein, 36 kDa, Equilibrative NBMPR-insensitive nucleoside transporter, Nucleoside transporter, ei-type, Delayed-early response protein 12, Solute carrier family 29 member 2, HNP36, DER12

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q14542

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

VAL-1221, CAS: 2145123-44-8

Clone ID

Clervonafusp Alfa

Data Image
  • SDS-PAGE
    SDS PAGE for Clervonafusp Alfa
References

Andexanet alfa for reversal of factor Xa inhibitor-associated anticoagulation, PMID: 31807265

Dornase alfa for cystic fibrosis, PMID: 30187450

Efficacy and Safety of Daprodustat Compared with Darbepoetin Alfa in Japanese Hemodialysis Patients with Anemia: A Randomized, Double-Blind, Phase 3 Trial, PMID: 32723804

Intravenous Epoetin Alfa-epbx versus Epoetin Alfa for Treatment of Anemia in End-Stage Kidney Disease, PMID: 29921734

Dornase Alfa, PMID: 32310478

Dornase alfa (Pulmozyme), PMID: 22990660

Lutropin alfa, PMID: 18627209

A pharmacokinetic evaluation of ropeginterferon alfa-2b in the treatment of polycythemia vera, PMID: 33118413

Epoetin Alfa, PMID: 30000431

Asfotase alfa for hypophosphatasia, PMID: 30670890

Susoctocog Alfa: A Review in Acquired Haemophilia A, PMID: 27098420

Andexanet alfa: A Novel Factor Xa Inhibitor Reversal Agent, PMID: 30813754

Interference of Asfotase Alfa in Immunoassays Employing Alkaline Phosphatase Technology, PMID: 32445383

Darbepoetin alfa, PMID: 11735636

Efmoroctocog alfa for haemophilia A, PMID: 30670892

Octocog alfa, plasma/albumin-free method, PMID: 16392876

Peginterferon Alfa, PMID: 29999705

XM17 Follitropin Alfa (Ovaleap(®)): A Review in Reproductive Endocrine Disorders, PMID: 27342604

Vestronidase Alfa, PMID: 30000015

Dornase alfa for cystic fibrosis, PMID: 27043279

Ropeginterferon alfa-2 b for the therapy of polycythemia vera, PMID: 32942868

Dornase Alfa, PMID: 29999662

Alglucosidase Alfa, PMID: 30000880

Trenonacog alfa for prophylaxis, on-demand and perioperative management of hemophilia B, PMID: 29172774

Turoctocog alfa (NovoEight®)--from design to clinical proof of concept, PMID: 24797664

Dornase Alfa for Non-Cystic Fibrosis Pediatric Pulmonary Atelectasis, PMID: 24811400

Cerliponase alfa for neuronal ceroid lipofuscinosis type 2 disease, PMID: 31363309

Turoctocog alfa: an evidence-based review of its potential in the treatment of hemophilia A, PMID: 25848213

Taliglucerase alfa: an enzyme replacement therapy using plant cell expression technology, PMID: 24630271

Sebelipase alfa: enzymatic replacement treatment for lysosomal acid lipase deficiency, PMID: 27376161

Interferon-alfa in the treatment of chronic hepatitis B, PMID: 15313664

Darbepoetin alfa: a novel erythropoiesis-stimulating protein, PMID: 12973399

Spotlight on taliglucerase alfa in the treatment of pediatric patients with type 1 Gaucher disease, PMID: 29388611

Agalsidase alfa: a review of its use in the management of Fabry disease, PMID: 22946754

Pharmacology of darbepoetin alfa, PMID: 17526547

Darbepoetin alfa: in patients with chemotherapy-related anaemia, PMID: 12749734

Interview with Dr Ghassan K Abou-Alfa, PMID: 27993088

Darbepoetin alfa: a novel erythropoiesis-stimulating protein, PMID: 12086553

Corifollitropin alfa: a review of its use in controlled ovarian stimulation for assisted reproduction, PMID: 21815699

Peginterferon alfa-2a: a review of approved and investigational uses, PMID: 15336466

Epoetin alfa. Clinical evolution of a pleiotropic cytokine, PMID: 14769622

Taliglucerase alfa: safety and efficacy across 6 clinical studies in adults and children with Gaucher disease, PMID: 29471850

Stability of Turoctocog Alfa, a Recombinant Factor VIII Product, during Continuous Infusion In Vitro, PMID: 33195971

Epoetin alfa in cancer patients: evidence-based guidelines, PMID: 11728799

Epoetin alfa versus darbepoetin alfa in chemotherapy-related anemia, PMID: 16332942

Real-world utilization of darbepoetin alfa in cancer chemotherapy patients, PMID: 28814194

Epoetin alfa as a supportive measure in hematologic malignancies, PMID: 12447849

Dornase alfa, PMID: 18031106

Darbepoetin alfa: a new approach to the treatment of chemotherapy-induced anaemia, PMID: 12783618

Epoetin alfa use in gynecology. Past, present and future, PMID: 11396388

Deucravacitinib Treatment for Psoriasis Complicated by Myelodysplastic Syndrome Without Exacerbation of the Underlying Hematologic Disorder: A Case Report., PMID:40519492

Rash associated with antibiotic administration in patients with infectious mononucleosis: a systematic review and meta-analysis., PMID:40512251

Integrative Analysis of Drug Co-Prescriptions in Peritoneal Dialysis Reveals Molecular Targets and Novel Strategies for Intervention., PMID:40507495

International Fibrolamellar Cancer Registry: Opportunities and Challenges., PMID:40499052

Rare types of alpha-1-antitrypsin deficency in the same family: Pi*Mmalton and Pi*Plowell., PMID:40497812

Persistent Atelectasis Prevalence and Incidence in Pediatric Critical Care., PMID:40497177

Validation of a handheld electrocardiogram 6 lead recorder to obtain chest lead equivalents: An Africa Heart Rhythm Association study., PMID:40496591

GX-I7, a long-acting IL-7, safely and effectively increased peripheral CD8+/CD4+ T cells and TILs in patients with locally advanced or metastatic solid tumours., PMID:40490502

Exploring Antimalarial Activity of Drugs using Weighted Atomic Vectors and Artificial Intelligence., PMID:40485561

Efimosfermin alfa (BOS-580), a long-acting FGF21 analogue, in participants with phenotypic metabolic dysfunction-associated steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2a trial., PMID:40484014

Enzyme replacement therapies in adults with Pompe disease: from trials to real-world data., PMID:40471681

Safety, pharmacokinetics and pharmacodynamics of Efsubaglutide Alfa in healthy participants: A randomised, dose-escalation phase 1 study., PMID:40470753

Successful treatment of hairy cell leukaemia with pegylated interferon-alpha-2A., PMID:40469412

Therapeutic efficacy of budesonide suspension combined with poractant alfa injection for neonatal respiratory distress syndrome and its effect on serum ferritin and PAI-1 expressions., PMID:40469168

Italian guidelines for the diagnosis and management of gastro-esophageal reflux disease: Joint consensus from the Italian Societies of: Gastroenterology and Endoscopy (SIGE), Neurogastroenterology and Motility (SINGEM), Hospital Gastroenterologists and Endoscopists (AIGO), Digestive Endoscopy (SIED), and General Medicine (SIMG)., PMID:40450492

The Mini-COMET Clinical Trial: Safety and Efficacy of Avalglucosidase Alfa after 97 Weeks of Treatment in Children with Infantile-Onset Pompe Disease Previously Treated with Alglucosidase Alfa., PMID:40449831

Preclinical Safety., PMID:40445826

Mean Corpuscular Volume Is Not a Reliable Predictor of Iron Deficiency in Patients With Chronic Kidney Disease: A Post-Hoc Analysis of the BRIGHTEN Trial., PMID:40443639

Mobility and Quality of Life in Children with Paediatric-Onset Hypophosphatasia Treated with Asfotase Alfa: Results from UK Managed Access Agreement., PMID:40439960

Less Invasive Surfactant Administration (LISA) versus Intubation Surfactant Extubation (InSurE) technique using higher volume surfactant in management of neonates with respiratory distress syndrome: an open-label randomized controlled trial., PMID:40439732

Life-Threatening Pharyngolaryngeal Hematoma in a Patient With Hemophilia A., PMID:40438813

Global Variation in Lipoprotein(a) Levels Among Patients With Coronary Heart Disease: Insights From the INTERASPIRE Study and Implications for Emerging Lp(a)-Lowering Therapies., PMID:40436467

Multistrain Probiotics Plus Vitamin D Improve Gut Barrier Function and Gut Microbiota Composition in Irritable Bowel Syndrome Without Constipation: Results from a Double-Blind, Randomized, Placebo-Controlled Trial., PMID:40431448

Exploring Multivalent Architectures for Binding and Stabilization of N-Acetylgalactosamine 6-Sulfatase., PMID:40430394

Current status of the immunogenicity of enzyme replacement therapy in fabry disease., PMID:40420145

Phenotypic and Genotypic Spectrum of Indian Patients with Hypophosphatasia., PMID:40416455

Therapeutic adherence in inflammatory bowel disease: User guide from a multidisciplinary modified Delphi consensus., PMID:40414777

[Acid sphingomyelinase deficiency: A review]., PMID:40414757

A global comparison of hepatitis B & C drug pricing., PMID:40414600

Fosfomycin for the treatment of patients with bacterial prostatitis: a systematic review., PMID:40410452

Markedly discordant hypophosphatasia in a young girl., PMID:40409424

A Theoretical and Experimental Study of Carbonized Lignin from Alfa Fibers as a Clay-Based Adsorbent., PMID:40402651

Robust longitudinal neuropsychological norms in Spanish individuals with nonpathological Alzheimer's disease biomarkers., PMID:40402619

Development and description of a porcine model of combat casualty care for traumatic-hemorrhagic shock research and medical training., PMID:40402209

Reversal of anticoagulation in patients with intracerebral haemorrhage related to oral anticoagulants: State of the evidence., PMID:40401655

Effects of erythropoietin on cardiac morphometry in exercised male and female adolescent rats., PMID:40400735

Good clinical practice recommendations for the diagnosis and treatment of functional dyspepsia: An expert review from the Asociación Mexicana de Gastroenterología., PMID:40399175

Defining clinically meaningful thresholds for forced vital capacity in patients with neuromuscular disorders: Lessons learned from the COMET study in Pompe disease., PMID:40397025

Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer, a study with 5-year follow-up: a plain language summary., PMID:40396643

Case of Gynandroblastoma of the Ovary with Raised AFP and Associated DICER 1 Mutation., PMID:40390890

Recurrence risk factors for chronic hepatitis B virus-infected patients who achieve functional cure with pegylated interferon-α-2b-based therapy: a multicenter pilot study., PMID:40390028

SGLT2 inhibitor with and without ALDosterone AntagonIst for heart failure with preserved ejection fraction: Design paper., PMID:40388563

Assisting the Diagnosis of Cirrhosis in Chronic Hepatitis C Patients Based on Machine Learning Algorithms: A Novel Non-Invasive Approach., PMID:40384539

Immune-mediated adverse events and overall survival with tremelimumab plus durvalumab and durvalumab monotherapy in unresectable HCC: HIMALAYA phase III randomized clinical trial., PMID:40384092

Real-world experience with the diagnosis of bile acid malabsorption (BAM) using serum 7-alpha-C4 and 48-hour stool bile acids., PMID:40383704

Venous thromboembolism in professional drivers of automatic transmission vehicles: an underestimated occupational risk?, PMID:40382788

Author's reply: "Comment on "Italian validation of the IBD-disk tool for the assessment of disability in inflammatory bowel diseases""., PMID:40379540

Long-Term Transfusion Independence with Luspatercept Versus Epoetin Alfa in Erythropoiesis-Stimulating Agent-Naive, Lower-Risk Myelodysplastic Syndromes in the COMMANDS Trial., PMID:40377899

Correction: Long-term safety and efficacy of ropeginterferon alfa-2b in Japanese patients with polycythemia vera., PMID:40377864

HBV-specific T-cell function is nonenhanced by tenofovir-induced decline in HBV viremia or HBsAg titer in chronic hepatitis B., PMID:40377525

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1486

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Research Grade Clervonafusp Alfa [DHC80002]
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