Catalog No.
EMJ93401
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
[Arg23-Ala215] & [Met23-Ser335]
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P43431 & P43432
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-12, IL12, IL-12, IL12 p70, NKSF
Hepatic encephalopathy induces anxiety and depression-like behaviors, cytokine dysfunction, BDNF down-regulation and neuropathological changes in mice., PMID:40381891
Inflammatory and neuropathological responses to Vesiculovirus carajas encephalitis in adult mice: variability, tolerance and resistance., PMID:40078875
Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalk., PMID:40001251
Abnormalities of IL-12 Family Cytokine Pathways in Autosomal Dominant Polycystic Kidney Disease Progression., PMID:39768851
The alpha 7 nicotinic acetylcholine receptor agonist PHA 568487 dampens inflammation in PBMCs from patients with newly discovered coronary artery disease., PMID:39269451
The role of cytokines in acute and chronic postsurgical pain after major musculoskeletal surgeries in a quaternary pediatric center., PMID:39222726
Dynamic cytokine profiles of bloodstream infection caused by Klebsiella pneumoniae in China., PMID:39182143
Alterations in gut microbiota and inflammatory cytokines after administration of antibiotics in mice., PMID:38899904
Higher Levels of Cytokines in Patients with Chronic Limb-Threatening Ischemia., PMID:38821475
Ocular surface immune transcriptome and tear cytokines in corneal infection patients., PMID:38694515
Genetic variation of FcγRIIa induces higher uptake of Leishmania infantum and modulates cytokine production by adherent mononuclear cells in vitro., PMID:38455048
Innate Immunity Activation in Newly Diagnosed Ileocolonic Crohn's Disease: A Cohort Study., PMID:38319717
MCT1 gene silencing enhances the immune effect of dendritic cells on cervical cancer cells., PMID:38180327
Assessment of biomarkers and clinical parameters as predictors of survival in patients with chagasic heart failure., PMID:38109427
The predictive role of early inflammation and oxidative stress and the dynamics of cytokines networks in post-stroke depression., PMID:38065474
Cytokine levels reflect tic symptoms more prominently during mild phases., PMID:37907857
[Changes and clinical significance of multiple cytokines in exhaled breath condensate in patients with severe inhalation injury]., PMID:37593859
The structures of two acidic polysaccharides from Gardenia jasminoides and their potential immunomodulatory activities., PMID:37481185
Dendritic cell activation and cytokine response in vaccine breakthrough TBE patients after in vitro stimulation with TBEV., PMID:37261350
Higher expression of Th1/Th2-related cytokines in the intestine of Wistar rats with ligature-induced periodontitis., PMID:36994797
Serum cytokine profiles predict outcomes of chronic hepatitis B patients discontinuing entecavir or tenofovir therapy., PMID:36872131
Nanoscale, antigen encounter-dependent, IL-12 delivery by CAR T cells plus PD-L1 blockade for cancer treatment., PMID:36855120
Low circulatory Fe and Se levels with a higher IL-6/IL-10 ratio provide nutritional immunity in tuberculosis., PMID:36713405
Inflammation and cell-to-cell communication, two related aspects in frailty., PMID:36289502
Increased seizure sensitivity in pregnant mice with genetic knockdown of acid sensing ion channel 2a is associated with impaired hippocampal inflammatory response., PMID:36187797
Myeloid autophagy genes protect mice against fatal TNF- and LPS-induced cytokine storm syndromes., PMID:36056542
Cestocidal activities of bioactive garlic compounds against Hymenolepis nana., PMID:35908577
First-Trimester Serum Cytokine Profile in Pregnancies Conceived After Assisted Reproductive Technology (ART) With Subsequent Pregnancy-Induced Hypertension., PMID:35844528
Decreased levels of cytokines implicate altered immune response in plasma of moderate-stage Alzheimer's disease patients., PMID:35842208
CCR6 expression reduces mouse survival upon malarial challenge with Plasmodium berghei NK65 strain., PMID:35730803
The Effects of 21-Day General Rehabilitation after Hip or Knee Surgical Implantation on Plasma Levels of Selected Interleukins, VEGF, TNF-α, PDGF-BB, and Eotaxin-1., PMID:35625533
The role of the meningeal lymphatic system in local meningeal inflammation and trigeminal nociception., PMID:35614095
Treatment of skin tumors with intratumoral interleukin 12 gene electrotransfer in the head and neck region: a first-in-human clinical trial protocol., PMID:35535423
Increased proinflammatory cytokines in tears correspond with conjunctival SARS-CoV-2 positivity in symptomatic COVID-19 patients., PMID:35508669
A novel fusion protein scaffold 18/12/TxM activates the IL-12, IL-15, and IL-18 receptors to induce human memory-like natural killer cells., PMID:35284622
Plasma secretome analyses identify IL-8 and nitrites as predictors of poor prognosis in nasopharyngeal carcinoma patients., PMID:35278812
Dietary fats modulate neuroinflammation in mucin 2 knock out mice model of spontaneous colitis., PMID:34973372
The diagnostic value of cytokines for the discrimination of vertebral osteomyelitis and degenerative diseases of the spine., PMID:34933239
The association between cytokines and psychomotor speed in a spectrum of psychotic disorders: A longitudinal study., PMID:34877553
Cytokine changes in fatal cases of paraquat poisoning., PMID:34786083
Yanning Syrup ameliorates the lipopolysaccharide-induced inflammation: Adjusting the gut microbiota, short-chain fatty acids, and the CD4+ T cell balance., PMID:34634365
Pro-inflammatory CXCL-10, TNF-α, IL-1β, and IL-6: biomarkers of SARS-CoV-2 infection., PMID:34554303
IL-10 and IL-12 (P70) Levels Predict the Risk of Covid-19 Progression in Hypertensive Patients: Insights From the BRACE-CORONA Trial., PMID:34386533
Role of Endosomal TLRs in Staphylococcus aureus Infection., PMID:34362834
Association of Sarcopenia and Gut Microbiota Composition in Older Patients with Advanced Chronic Kidney Disease, Investigation of the Interactions with Uremic Toxins, Inflammation and Oxidative Stress., PMID:34357944
Large scale cytokine profiling uncovers elevated IL12-p70 and IL-17A in severe pediatric acute respiratory distress syndrome., PMID:34239039
Development of a Fluorescent Assay to Search New Drugs Using Stable tdTomato-Leishmania, and the Selection of Galangin as a Candidate With Anti-Leishmanial Activity., PMID:34150675
Functional changes of immune cells: signal of immune tolerance of the ectopic lesions in endometriosis?, PMID:34103260
The impact of ExHp-CD (outer membrane vesicles) released from Helicobacter pylori SS1 on macrophage RAW 264.7 cells and their immunogenic potential., PMID:34048813
Deficiency of ataxia-telangiectasia mutated kinase modulates functional and biochemical parameters of the heart in response to Western-type diet., PMID:33929897
For research use only. Not for human or drug use.
