Catalog No.
YHJ91601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys901-Gly1100
Predicted molecular weight
48.57 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y6N6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Laminin-15 subunit gamma, Laminin subunit gamma-3, Laminin-14 subunit gamma, LAMC3, Laminin-12 subunit gamma, laminin 12, laminin 213, laminin 13, laminin 323, laminin 14, laminin 423, laminin 15, laminin 523
Transplantation of peripheral nerve tissueoid based on a decellularized optic nerve scaffold to restore rat hindlimb sensory and movement functions., PMID:39531746
Exploring unsolved cases of lissencephaly spectrum: integrating exome and genome sequencing for higher diagnostic yield., PMID:39123069
Novel LAMC3 pathogenic variant enriched in Finnish population causes malformations of cortical development and severe epilepsy., PMID:38758065
Identification of EMT-associated prognostic features among grade II/III gliomas., PMID:38307919
Identification of Basement Membrane Genes and Related Molecular Subtypes in Nonalcoholic Fatty Liver Disease., PMID:37268001
A Genome-Wide Association Study Identified Novel Genetic Susceptibility Loci for Oral Cancer in Taiwan., PMID:36769103
A novel risk model based on the correlation between the expression of basement membrane genes and immune infiltration to predict the invasiveness of pituitary adenomas., PMID:36686480
Identification of a basement membrane-related gene signature for predicting prognosis and estimating the tumor immune microenvironment in breast cancer., PMID:36531485
What Do the Transcriptome and Proteome of Menstrual Blood-Derived Mesenchymal Stem Cells Tell Us about Endometriosis?, PMID:36232817
Genome-Wide Identification of Laminin Family Related to Follicular Pseudoplacenta Development in Black Rockfish (Sebastes schlegelii)., PMID:36142434
Dynamic transcriptome profiling reveals essential roles of the receptor tyrosine kinases (RTK) family in feather development of duck., PMID:35383522
Comparative analysis of the autism‑related variants between different autistic children in a family pedigree., PMID:34368859
Variants in LAMC3 Causes Occipital Cortical Malformation., PMID:34354730
[Relationships between decreased LAMC3 and poor prognosis in ovarian cancer]., PMID:34304441
Cortical connectivity in the face of congenital structural changes-A case of homozygous LAMC3 mutation., PMID:34124859
The pharmacodynamic and differential gene expression analysis of PPAR α/δ agonist GFT505 in CDAHFD-induced NASH model., PMID:33326461
A novel splice variant expands the LAMC3-associated cortical phenotype to frontal only polymicrogyria and adult-onset epilepsy., PMID:32902107
Quantitative Proteomic Profiling of Mitochondrial Toxicants in a Human Cardiomyocyte Cell Line., PMID:32733541
Retinal endothelial cell phenotypic modifications during experimental autoimmune uveitis: a transcriptomic approach., PMID:32183784
A novel messenger RNA and long noncoding RNA signature associated with the progression of nonmuscle invasive bladder cancer., PMID:30426560
Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation., PMID:29795281
Homozygous LAMC3 mutation links to structural and functional changes in visual attention networks., PMID:29626609
Knockdown of Laminin gamma-3 (Lamc3) impairs motoneuron guidance in the zebrafish embryo., PMID:29417095
A novel mutation in LAMC3 associated with generalized polymicrogyria of the cortex and epilepsy., PMID:29247375
Laminin-Dependent Interaction between Astrocytes and Microglia: A Role in Retinal Angiogenesis., PMID:28697326
Family-based genome scan for age at onset of late-onset Alzheimer's disease in whole exome sequencing data., PMID:26394601
Sensory rewiring in an echolocator: genome-wide modification of retinogenic and auditory genes in the bat Myotis davidii., PMID:25096539
Transcriptome analysis of skin photoaging in chinese females reveals the involvement of skin homeostasis and metabolic changes., PMID:23637934
Exome resequencing identifies potential tumor-suppressor genes that predispose to colorectal cancer., PMID:23585368
Laminins containing the β2 and γ3 chains regulate astrocyte migration and angiogenesis in the retina., PMID:23571221
β2 and γ3 laminins are critical cortical basement membrane components: ablation of Lamb2 and Lamc3 genes disrupts cortical lamination and produces dysplasia., PMID:22961762
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations., PMID:22495309
The γ3 chain of laminin is widely but differentially expressed in murine basement membranes: expression and functional studies., PMID:22222602
Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations., PMID:21572417
Recessive LAMC3 mutations cause malformations of occipital cortical development., PMID:21572413
Genetic deletion of laminin isoforms β2 and γ3 induces a reduction in Kir4.1 and aquaporin-4 expression and function in the retina., PMID:21283711
Defective formation of the inner limiting membrane in laminin beta2- and gamma3-null mice produces retinal dysplasia., PMID:19907020
Laminin isoforms containing the gamma3 chain are unable to bind to integrins due to the absence of the glutamic acid residue conserved in the C-terminal regions of the gamma1 and gamma2 chains., PMID:18697739
A comprehensive survey of the laminins and collagens type IV expressed in mouse Leydig cells and their regulation by LH/hCG., PMID:18367508
Binding of netrin-4 to laminin short arms regulates basement membrane assembly., PMID:17588941
Laminin gamma3 chain binds to nidogen and is located in murine basement membranes., PMID:15824114
Interactions of proteases, protease inhibitors, and the beta1 integrin/laminin gamma3 protein complex in the regulation of ectoplasmic specialization dynamics in the rat testis., PMID:14645107
Structural analysis and mutation detection strategy for the human LAMC3 gene., PMID:11162474
Characterization and expression of the laminin gamma3 chain: a novel, non-basement membrane-associated, laminin chain., PMID:10225960
For research use only. Not for human or drug use.
