Catalog No.
YHJ91001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro318-His513
Predicted molecular weight
24.74 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y6A1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
POMT1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, Protein O-mannosyl-transferase 1
Novel POMT2 variants associated with limb-girdle muscular dystrophy R14: genetic, histological and functional studies., PMID:40102912
Transcriptome analysis reveals modulations in glycosylation profiles of the mucosal barrier and their potential interaction with gut microbiota in weaned piglets., PMID:39990197
Sarcolemma resilience and skeletal muscle health require O-mannosylation of dystroglycan., PMID:39789642
Identification of biomarkers for chronic lymphocytic leukemia risk: a proteome-wide Mendelian randomization study., PMID:39751938
Reclassifying a Novel POMT1 Variant by Integrating Functional Analysis and Bioinformatics: Implications for Preimplantation Genetic Testing., PMID:39739288
Differential substrate preferences IN ACTINOBACTERIAL protein O-MANNOSYLTRANSFERASES and alteration of protein-O-MANNOSYLATION by choice of secretion pathway., PMID:39673494
Neurexin facilitates glycosylation of Dystroglycan to sustain muscle architecture and function in Drosophila., PMID:39521920
Global View of Domain-Specific O-Linked Mannose Glycosylation in Glycoengineered Cells., PMID:38851451
Genetic blueprint of congenital muscular dystrophies with brain malformations in Egypt: A report of 11 families., PMID:38296890
Removal of pomt1 in zebrafish leads to loss of α-dystroglycan glycosylation and dystroglycanopathy phenotypes., PMID:38272461
Effect of ATG8 or SAC1 deficiency on the cell proliferation and lifespan of the long-lived PMT1 deficiency yeast cells., PMID:38258560
Molecular investigation in individuals with orofacial clefts and microphthalmia-anophthalmia-coloboma spectrum., PMID:37932364
Development of a novel target-based cell assay, reporter of the activity of Mycobacterium tuberculosis protein-O-mannosyltransferase., PMID:37698262
Metabolic Cardiomyopathies and Cardiac Defects in Inherited Disorders of Carbohydrate Metabolism: A Systematic Review., PMID:37239976
The SHDRA syndrome-associated gene TMEM260 encodes a protein-specific O-mannosyltransferase., PMID:37186866
Broad spectrum of phenotype and genotype in Korean α-dystroglycan related muscular dystrophy presenting to a tertiary pediatric neuromuscular center., PMID:37087885
Systematic analysis of the BET family in adrenocortical carcinoma: The expression, prognosis, gene regulation network, and regulation targets., PMID:36793283
Protein tyrosine phosphatase 69D is a substrate of protein O-mannosyltransferases 1-2 that is required for the wiring of sensory axons in Drosophila., PMID:36634851
Deletion of POMT2 in Zebrafish Causes Degeneration of Photoreceptors., PMID:36499139
Involvement of abnormal dystroglycan expression and matriglycan levels in cancer pathogenesis., PMID:36494657
Clinical exome sequencing identifies novel compound heterozygous mutations of the POMT2 gene in patients with limb-girdle muscular dystrophy., PMID:36217604
Fetal Presentation of Walker-Warburg Syndrome with Compound Heterozygous POMT2 Missense Mutations., PMID:36048137
Seizures and EEG characteristics in a cohort of pediatric patients with dystroglycanopathies., PMID:35863218
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
Protein O-mannosyltransferase Rv1002c contributes to low cell permeability, biofilm formation in vitro, and mycobacterial survival in mice., PMID:34978741
Alanine-scanning mutagenesis of protein mannosyl-transferase from Streptomyces coelicolor reveals strong activity-stability correlation., PMID:34676818
POMT1 and POMT2 gene mutations result in 2 cases of alpha-dystroglycanopathy., PMID:34565739
Hyperosmotic medium partially restores the growth defect and the impaired production of sterigmatocystin of an Aspergillus nidulans ΔpmtC mutant in a HogA-independent manner., PMID:34549285
The Evaluation of UPro as a New Nutrient on High-Quality Egg Production From the Perspective of Egg Properties, Intestinal Histomorphology, and Oviduct Function of Laying Hens., PMID:34490324
Effect of Protein O-Mannosyltransferase (MSMEG_5447) on M. smegmatis and Its Survival in Macrophages., PMID:34276591
Retinal Proteomics of a Mouse Model of Dystroglycanopathies Reveals Molecular Alterations in Photoreceptors., PMID:34027671
A homozygous mutation in the POMT2 gene in four siblings with limb-girdle muscular dystrophy 2N., PMID:34013233
Structural, Evolutionary, and Functional Analysis of the Protein O-Mannosyltransferase Family in Pathogenic Fungi., PMID:33922798
Enhanced influenza A H1N1 T cell epitope recognition and cross-reactivity to protein-O-mannosyltransferase 1 in Pandemrix-associated narcolepsy type 1., PMID:33863907
Functional implications of MIR domains in protein O-mannosylation., PMID:33357379
Genetic variations and clinical spectrum of dystroglycanopathy in a large cohort of Chinese patients., PMID:33200426
Neuroimaging manifestations and genetic heterogeneity of Walker-Warburg syndrome in Saudi patients., PMID:33199158
MaPmt1, a protein O-mannosyltransferase, contributes to virulence through governing the appressorium turgor pressure in Metarhizium acridum., PMID:33130254
Protein O-mannosylation affects protein secretion, cell wall integrity and morphogenesis in Trichoderma reesei., PMID:32758529
Reporting one very rare pathogenic variation c.1106G>A in POMT2 gene., PMID:32494558
Translational Regulation of Pmt1 and Pmt2 by Bfr1 Affects Unfolded Protein O-Mannosylation., PMID:31835530
Genetical and O-glycoproteomic analyses reveal the roles of three protein O-mannosyltransferases in phytopathogen Fusarium oxysporum f.sp. cucumerinum., PMID:31648060
Just Expect It: Compound Heterozygous Variants of POMT1 in a Consanguineous Family-The Role of Next Generation Sequencing in Neuromuscular Disorders., PMID:31627234
Regulating colonic dendritic cells by commensal glycosylated large surface layer protein A to sustain gut homeostasis against pathogenic inflammation., PMID:31619761
Live Imaging and Analysis of Muscle Contractions in Drosophila Embryo., PMID:31355800
Clinical long-time course, novel mutations and genotype-phenotype correlation in a cohort of 27 families with POMT1-related disorders., PMID:31311558
Structure of the eukaryotic protein O-mannosyltransferase Pmt1-Pmt2 complex., PMID:31285605
Characterization of the Streptomyces coelicolor Glycoproteome Reveals Glycoproteins Important for Cell Wall Biogenesis., PMID:31239379
Multiple distinct O-Mannosylation pathways in eukaryotes., PMID:30999272
For research use only. Not for human or drug use.
