Catalog No.
YHJ89701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg54-Glu283
Predicted molecular weight
28.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y5S8
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NOH1, NADPH oxidase 1, NOH-1, NOX-1, NOX1, Mitogenic oxidase 1, MOX1, MOX-1, NADH/NADPH mitogenic oxidase subunit P65-MOX
Smooth muscle LRRC8A knockout preserves vascular function in AngII hypertension., PMID:40463256
Alleviation of dextran sulfate sodium (DSS)-induced colitis in mice through the antioxidative effects of muscone via the MyD88/p38 MAPK signalling pathway., PMID:40452925
Cmtm4 Deficiency Inhibits Helicobacter pylori-Induced Gastric Carcinogenesis., PMID:40432275
A potential role for NADPH oxidase (NOX1/2) in mutant huntingtin-induced anomalous neurite outgrowth., PMID:40412581
Jian-pi Qu-tan Hua-yu Decoction improves oxidative stress-induced inflammation in endothelial cells in atherosclerotic ApoE-/- mice through the NOX1-ROS-ERK1/2 pathway., PMID:40398180
Overstretch causes lipid accumulation in vascular smooth muscle cells dependent on NADPH oxidase 1., PMID:40395775
Development of SOCS1 mimetics as novel approach to harmonize inflammation, oxidative stress, and fibrogenesis in metabolic dysfunction-associated steatotic liver disease., PMID:40373621
Multiple targets directed screening of compounds from northeastern Brazilian fruits with activity in oxidative stress pathways associated with vascular damage throughout ageing., PMID:40337800
NOX4-driven mitochondrial oxidative stress in aging promotes myocardial remodeling and increases susceptibility to ventricular tachyarrhythmia., PMID:40320218
Differential inflammation, oxidative stress and cardiovascular damage markers of nano- and micro-particle exposure in mice: Implications for human disease burden., PMID:40319735
FBXO38 Regulates Nox1 Stability to Reduce Vascular Endothelial Damage Induced by Low Oscillatory Shear Stress., PMID:40313652
Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia., PMID:40309008
MCT4 inhibition attenuates inflammatory response to Mycobacterium avium paratuberculosis infection and restores intestinal epithelial integrity in vitro., PMID:40297589
Norepinephrine promotes oxidative stress in vascular adventitial fibroblasts via PKC/NFκB-mediated NOX2 upregulation., PMID:40269356
Unveiling the Therapeutic Potential of Dulaglutide in Mitigating Tacrolimus-Induced Nephrotoxicity Through Targeting the miR-22/HMGB-1/TLR4/MyD88/NF-κB Trajectory., PMID:40205909
Alleviation of accelerated diabetic atherogenesis in STZ-treated apoE/NOX1 DKO mice, apoE-/-/tg-EC-DHFR mice, and by folic acid., PMID:40184644
Therapeutic S100A8/A9 inhibition reduces NADPH oxidase expression, reactive oxygen species production and NLRP3 inflammasome priming in the ischemic myocardium., PMID:40180274
Study the Impact of NADPH oxidase1,TNF-alpha and Cyclooxygenase-2 On Colon Cancer Patients., PMID:40156404
p53-binding Protein Inhibits Intracellular Reactive Oxygen Species by Increasing the Expression of Metallothioneins., PMID:40155029
Redox regulation of lung endothelial PERK, unfolded protein response (UPR) and proliferation via NOX1: Targeted inhibition as a potential therapy for PAH., PMID:40154102
Exploring the potential mechanism of atorvastatin in regulating ferroptosis as a treatment for heart failure based on network pharmacology., PMID:40116871
Oxidized low-density lipoprotein induced ferroptosis in nucleus pulposus cell contributes to intervertebral disc degeneration via LOX-1/NF-κB/NOX signal., PMID:40112598
Formyl peptide receptor 1 signaling strength orchestrates the switch from pro-inflammatory to pro-resolving responses: The way to exert its anti-angiogenic and tumor suppressor functions., PMID:40112515
Ophiopogonin D from Ophiopogon japonicas-induced USP25 Activity to Reduce Ferroptosis of Macrophage in Acute Lung Injury by the Inhibition of Bound Rac1 and Nox1 Complex., PMID:40099394
SET7 lysine methyltransferase mediates the up-regulation of NADPH oxidase expression, oxidative stress, and NLRP3 inflammasome priming in atherosclerosis., PMID:40098010
Sodium-glucose co-transporters (SGLT2) inhibitors prevent lipid droplets formation in vascular inflammation or lipid overload by SGLT2-independent mechanism., PMID:40088775
NADPH oxidase subunit p22phox: A marker of oxidase-dependent oxidative stress and target for stress suppression in nonphagocytic cells., PMID:40081522
Vaccarin Ameliorates Renal Fibrosis by Inhibiting Ferroptosis via Nrf2/SLC7A11/GPX4 Signaling Pathway., PMID:40066086
Reduced glutathione enhances adipose tissue-derived mesenchymal stem cell engraftment efficiency for liver fibrosis by targeting TGFβ1/SMAD3/NOX4 pathway., PMID:40060764
Grape pomace extract attenuates high fat diet-induced endotoxemia and liver steatosis in mice., PMID:40029158
TNFRSF1A and NCF1 May Act as Hub Genes in Mastitis., PMID:40028770
Nicotine Influence on Vascular and Neurocognitive Function with In-utero Electronic Cigarette Exposure., PMID:40027767
Metabolic Rewiring in the Face of Genomic Assault: Integrating DNA Damage Response and Cellular Metabolism., PMID:40001471
Comprehensive Metabolomic and Bioactivity Profiling of Zingiberaceae Species From Manipur: Elucidating Antidiabetic and Antioxidant Mechanisms Through In Vitro and In Silico Approaches., PMID:39993938
Ginger protects against vein graft remodeling by precisely modulating ferroptotic stress in vascular smooth muscle cell dedifferentiation., PMID:39974619
Febuxostat protects from Doxorubicin induced hepatotoxicity in rats via regulation of NF-κB p65/NLRP3 inflammasome and SIRT-1/AMPK pathways., PMID:39951115
Phillyrin regulates the JAK2/STAT3 signaling pathway by inhibiting TOP2A expression to accelerate ferroptosis in hepatocellular carcinoma., PMID:39950325
Rpl13a snoRNAs-regulated NADPH oxidase 1-dependent ROS generation: A novel RBC pathway mediating complement C3a deposition and triggering thrombosis in aging and venous blood clotting disorders., PMID:39938620
Dynamic Activation of NADPH Oxidases in Immune Responses Modulates Differentiation, Function, and Lifespan of Plasma Cells., PMID:39931760
CD4+ T Cells Expressing Viral Proteins Induce HIV-Associated Endothelial Dysfunction and Hypertension Through Interleukin 1α-Mediated Increases in Endothelial NADPH Oxidase 1., PMID:39907014
Increased NOX-dependent ROS production and proportionally enhanced antioxidant response in white adipose tissue of male rats., PMID:39876964
Kurarinone Mitigates LPS-Induced Inflammatory Osteolysis by Inhibiting Osteoclastogenesis Through the Reduction of ROS Levels and Suppression of the PI3K/AKT Signaling Pathway., PMID:39871069
Extracorporeal shockwave therapy rescued mouse critical limb ischemia via upregulating GPR120 against inflammation and promoting angiogenesis for restoring the blood flow in ischemic zone-experimental study., PMID:39869384
Characterisation of periorbital mechanical allodynia in the reserpine-induced fibromyalgia model in mice: The role of the Schwann cell TRPA1/NOX1 signalling pathway., PMID:39842732
Chrysoeriol: a natural RANKL inhibitor targeting osteoclastogenesis and ROS regulation for osteoporosis therapy., PMID:39755833
Endothelial CD38-induced endothelial-to-mesenchymal transition is a pivotal driver in pulmonary fibrosis., PMID:39725783
Nox1/PAK1 is required for angiotensin II-induced vascular inflammation and abdominal aortic aneurysm formation., PMID:39721498
[Inhibition of PRDX1 protein expression and promotion of apoptosis of colorectal cancer cells by furanodienone via inducing ROS generation from NOX4-derived mitochondria]., PMID:39701785
NOX proteins and ROS generation: role in invadopodia formation and cancer cell invasion., PMID:39696702
C-Peptide Ameliorates Particulate Matter 2.5-Induced Skin Cell Apoptosis by Inhibiting NADPH Oxidation., PMID:39690967
For research use only. Not for human or drug use.
