Catalog No.
YHJ89601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile429-Gln642
Predicted molecular weight
27.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y5R2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Membrane-type-5 matrix metalloproteinase, MMP-24, MT5-MMP, MT5MMP, MMP24, MTMMP5, MT-MMP 5, Matrix metalloproteinase-24, Membrane-type matrix metalloproteinase 5
The Effect of Curcumin on the Activity of MMP-17 and MMP-24 in Hepatocytes of Mice Exposed to Thioacetamide., PMID:40330566
The m5C reader protein Ybx1 promotes axon growth by regulating local translation in axons., PMID:39611865
Genetic Influence of the Brain on Muscle Structure: A Mendelian Randomization Study of Sarcopenia., PMID:39535371
Functional Analysis of RE1 Silencing Transcription Factor as a Putative Tumor Suppressor in Human Endometrial Cancer., PMID:39273639
Eta-secretase-like processing of the amyloid precursor protein (APP) by the rhomboid protease RHBDL4., PMID:38992438
Dynamics of Chromatin Opening across Larval Development in the Urochordate Ascidian Ciona savignyi., PMID:38474039
Salidroside inhibited the proliferation of gastric cancer cells through up-regulating tumor suppressor miR-1343-3p and down-regulating MAP3K6/MMP24 signal molecules., PMID:38436092
PCSK6 exacerbates Alzheimer's disease pathogenesis by promoting MT5-MMP maturation., PMID:38216110
KCTD4 interacts with CLIC1 to disrupt calcium homeostasis and promote metastasis in esophageal cancer., PMID:37799381
Muscle Regeneration in Holothurians without the Upregulation of Muscle Genes., PMID:36555677
Matrix metalloproteinase 1 is a poor prognostic biomarker for patients with hepatocellular carcinoma., PMID:36169759
Genome-wide association study of actinic keratosis identifies new susceptibility loci implicated in pigmentation and immune regulation pathways., PMID:35449187
Genome-Wide Association Study of the Relationship Between Matrix Metalloproteinases and Intracranial Aneurysms., PMID:35196751
Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression., PMID:35177031
Landscape Analysis of Matrix Metalloproteinases Unveils Key Prognostic Markers for Patients With Breast Cancer., PMID:35069702
Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC)., PMID:35062057
Inflammatory Bowel Disease Risk Variants Are Associated with an Increased Risk of Skin Cancer., PMID:35018451
Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals., PMID:34852643
Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes., PMID:34359875
MT5-MMP controls APP and β-CTF/C99 metabolism through proteolytic-dependent and -independent mechanisms relevant for Alzheimer's disease., PMID:34117802
MMP24 Contributes to Neuropathic Pain in an FTO-Dependent Manner in the Spinal Cord Neurons., PMID:33995105
Identification of a 6-Gene Signature Associated with Resistance to Tyrosine Kinase Inhibitors: Prognosis for Clear Cell Renal Cell Carcinoma., PMID:33296352
Clarification of the Role of miR-9 in the Angiogenesis, Migration, and Autophagy of Endothelial Progenitor Cells Through RNA Sequence Analysis., PMID:33028108
The prognostic value and potential mechanism of Matrix Metalloproteinases among Prostate Cancer., PMID:32669958
MMP24 as a Target of YAP is a Potential Prognostic Factor in Cancer Patients., PMID:32093160
CIC Mutation as a Molecular Mechanism of Acquired Resistance to Combined BRAF-MEK Inhibition in Extramedullary Multiple Myeloma with Central Nervous System Involvement., PMID:32043788
Role of Cyclosporine in Gingival Hyperplasia: An In Vitro Study on Gingival Fibroblasts., PMID:31963361
Extracellular gamma-synuclein promotes tumor cell motility by activating β1 integrin-focal adhesion kinase signaling pathway and increasing matrix metalloproteinase-24, -2 protein secretion., PMID:29903032
Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats., PMID:28990064
Viral Infection Identifies Micropeptides Differentially Regulated in smORF-Containing lncRNAs., PMID:28825667
Biological function evaluation and effects of laser micro-pore burn-denatured acellular dermal matrix., PMID:28823469
Novel genes involved in pathophysiology of gonadotropin-dependent adrenal tumors in mice., PMID:28131743
Metastasis: From head to tail., PMID:28055306
Inactivation of Capicua drives cancer metastasis., PMID:27869830
MT5-MMP, just a new APP processing proteinase in Alzheimer's disease?, PMID:27349644
GATA4 Regulates Blood-Testis Barrier Function and Lactate Metabolism in Mouse Sertoli Cells., PMID:26974005
η-Secretase processing of APP inhibits neuronal activity in the hippocampus., PMID:26322584
Association Study of GWAS-Derived Loci with Height in Brazilian Children: Importance of MAP3K3, MMP24 and IGF1R Polymorphisms for Height Variation., PMID:26304632
MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease., PMID:26202697
Neural stem cell quiescence comes to an un-sticky end., PMID:24981635
MT5-MMP regulates adult neural stem cell functional quiescence through the cleavage of N-cadherin., PMID:24952463
Lack of clinical manifestations in asymptomatic dengue infection is attributed to broad down-regulation and selective up-regulation of host defence response genes., PMID:24727912
Targeted deletion of Sox10 by Wnt1-cre defects neuronal migration and projection in the mouse inner ear., PMID:24718611
Expression of the matrix metalloproteases 2, 14, 24, and 25 and tissue inhibitor 3 as potential molecular markers in advanced human gastric cancer., PMID:24669030
Expression of matrix metalloproteinases in human breast cancer tissues., PMID:23568046
MT-MMPs in pre-eclamptic placenta: relationship to soluble endoglin production., PMID:23261267
MT5-MMP, ADAM-10, and N-cadherin act in concert to facilitate synapse reorganization after traumatic brain injury., PMID:22489706
Matrix metalloproteinase 14 and 19 expression is associated with thoracic aortic aneurysms., PMID:21955474
Matrix metalloproteinase proteolysis of the mycobacterial HSP65 protein as a potential source of immunogenic peptides in human tuberculosis., PMID:21752195
Comparative expression pattern of Matrix-Metalloproteinases in human glioblastoma cell-lines and primary cultures., PMID:21067565
For research use only. Not for human or drug use.
