Catalog No.
YHJ86501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro350-Lys631
Predicted molecular weight
33.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y2T1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Axin-like protein, AXIN2, Axin-2, Axis inhibition protein 2, Axil, Conductin
The Junctional Epithelium Attachment Is Regulated by Wnt Signaling., PMID:40492573
Crosstalk of injured podocytes with parietal epithelial cells through Wnt4/β-Catenin signaling., PMID:40467671
The critical role of Id2 gene in mesenchymal stem cell therapy for colitis through regulating immune response and microbiota., PMID:40450917
The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of changes in β-catenin abundance., PMID:40424469
Dendritic Poly(l-lysine)-Based Nanoparticle Loading with siDNMT1 to Alleviate Basal Cell Carcinoma Progression by Inhibiting Methylation of AXIN2., PMID:40338193
Phosphatidylinositol 3-Kinase Signaling Enhances Intestinal Crypt Epithelial Cell Recovery after Radiation., PMID:40316215
Identification and Functional Analysis of Novel Mutations in AXIN2 and LRP6 Linked With Non-Syndromic Tooth Agenesis., PMID:40293036
FBXW2 inhibits the progression of gastric cancer via promoting β-catenin ubiquitylation., PMID:40225854
Berberine promotes hair growth by targeting Axin2 and activating Wnt/β-catenin pathway., PMID:40220423
Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies., PMID:40189599
Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis., PMID:40173259
Implant derived high local concentration of magnesium inhibits tumorigenicity of osteosarcoma., PMID:40132359
In-vitro evaluation of the effect of okra (Abelmoschus esculentus L.) extract on periodontal cells: a comprehensive study of cellular and molecular impacts., PMID:40016714
In Vivo Efficacy of a Macrocyclic Peptoid-Peptide Hybrid That Selectively Modulates the Beta-Catenin/TCF Interaction to Inhibit Prostate Cancer., PMID:39956770
Casein Glycomacropeptide Regulates Gene Expression in Intestinal Epithelial Cells: Effect of Simulated Gastrointestinal Digestion and Peptide Microencapsulation., PMID:39921639
A rare deleterious missense mutation in the AXIN2 gene in Chinese women with polycystic ovary syndrome., PMID:39912710
A missense variant in the SOX5 gene (c.221C > T) is associated with intellectual disability., PMID:39905544
Vdr mediates Wnt signaling pathway to regulate odontoblasts differentiation during dentin apposition., PMID:39894431
Unlocking the potential of Calculus bovis: A breakthrough in liver cancer treatment via Wnt/β-catenin pathway modulation., PMID:39877712
Moracin M promotes hair regeneration through activation of the WNT/β-catenin pathway and angiogenesis., PMID:39853610
Single-Cell RNA Sequencing Reveals LEF1-Driven Wnt Pathway Activation as a Shared Oncogenic Program in Hepatoblastoma and Medulloblastoma., PMID:39851951
Targeting the Hippo and Rap1 signaling pathways: the anti-proliferative effects of curcumin in colorectal cancer cell lines., PMID:39779534
High Glucose Sensitizes Male and Female Rat Cardiomyocytes to Wnt/β-Catenin Signaling., PMID:39766346
The mechanism of exosomes of BMSCs modified with Bu Shen Yi Sui capsule in promoting remyelination via regulating miR-15b/Wnt signaling pathway-mediated differentiation of oligodendrocytes., PMID:39733800
The evolution of cephalic fins in manta rays and their relatives: functional evidence for initiation of domain splitting and modulation of the Wnt signaling pathway in the pectoral fin AER of the little skate., PMID:39731200
Disturbed Spatial WNT Activation-A Potential Driver of the Reticularized Skin Phenotype in Systemic Sclerosis., PMID:39722197
Investigating the role of Wnt3a and Wnt5a as critical factors of hepatic stellate cell activation in acute toxicant-induced liver injury., PMID:39707064
A Putative Frizzled 7-Targeting Compound Acts as a Firefly Luciferase Inhibitor., PMID:39670643
Exploring the genetics, mechanisms, and therapeutic innovations in non-syndromic tooth agenesis., PMID:39657464
A phase I dose-escalation study of LRP5/6 antagonist BI 905677 in patients with advanced solid tumors., PMID:39617530
AXIN2 is a non-redundant regulator of AXIN1 stability and β-catenin in colorectal cancer cells., PMID:39587396
[DDX5-Targeting Fragile X Mental Retardation Protein Regulates the Wnt/β-catenin Signaling Pathway to Promote Epithelial Mesenchymal Transition in Breast Cancer]., PMID:39507961
Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids., PMID:39487295
Current advances in understanding endometrial epithelial cell biology and therapeutic applications for intrauterine adhesion., PMID:39456113
RSPO/LGR signaling regulates proliferation of adult hippocampal neural stem cells., PMID:39432578
Exploring DIX-DIX Homo- and Hetero-Oligomers in Wnt Signaling with AlphaFold2., PMID:39404409
The Effect of Tideglusib Application on Type 1 and Type 3 Collagen Expressions by Human Dental-Pulp Derived Stem Cells: A Preliminary Study., PMID:39348326
Effects of imidazole derivatives on cellular proliferation and apoptosis in myeloid leukemia., PMID:39342179
Development of a zoledronate-modified functional alginate hydrogel with effects of promoting osteogenesis for potential osteoporosis treatment., PMID:39299416
OSR1 suppresses oral squamous cell carcinoma proliferation and migration via the AXIN2/β-catenin pathway., PMID:39286942
CasRx-based Wnt activation promotes alveolar regeneration while ameliorating pulmonary fibrosis in a mouse model of lung injury., PMID:39245939
Znrf3 exon 2 deletion mice do not recapitulate congenital adrenal hypoplasia., PMID:39235352
What could be the role of genetic tests and machine learning of AXIN2 variant dominance in non-syndromic hypodontia? A case-control study in orthodontically treated patients., PMID:39183201
Positive Regulation of Osteoblast Proliferation and Differentiation in MC3T3- E1 Cells by 7,3',4'-Trimethoxyflavone., PMID:39129721
Hereditary Colorectal Cancer and Polyposis Syndromes Caused by Variants in Uncommon Genes., PMID:39120161
Screening and identification of miRNAs negatively regulating FAM83A/Wnt/β-catenin signaling pathway in non-small cell lung cancer., PMID:39075121
Molecular pathogenesis of microsatellite instability-high early-stage colorectal adenocarcinoma in India., PMID:39042905
BRCA Status Dictates Wnt Responsiveness in Epithelial Ovarian Cancer., PMID:39028933
AXIN2 promotes degradation of AXIN1 through tankyrase in colorectal cancer cells., PMID:39022865
Disparate effects of sclerostin deletion on alveolar bone and cellular cementum in mice., PMID:39012429
For research use only. Not for human or drug use.
