Catalog No.
YHJ80201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp230-Arg344
Predicted molecular weight
40.46 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9ULE0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA1280, Protein WWC3, WWC3
WWC2 expression in the testis: Implications for spermatogenesis and male fertility., PMID:37086090
Proteogenomic landscape and clinical characterization of GH-producing pituitary adenomas/somatotroph pituitary neuroendocrine tumors., PMID:36435867
Antitumor Activity of lncRNA NBAT-1 via Inhibition of miR-4504 to Target to WWC3 in Oxaliplatin-Resistant Colorectal Carcinoma., PMID:35494512
Proteomic Analysis of Endometrial Cancer Tissues from Patients with Type 2 Diabetes Mellitus., PMID:35454982
Reciprocal Regulation of Hippo and WBP2 Signalling-Implications in Cancer Therapy., PMID:34831354
WBP2 negatively regulates the Hippo pathway by competitively binding to WWC3 with LATS1 to promote non-small cell lung cancer progression., PMID:33837178
Circ_WWC3 overexpression decelerates the progression of osteosarcoma by regulating miR-421/PDE7B axis., PMID:33817314
WWC Proteins: Important Regulators of Hippo Signaling in Cancer., PMID:33467643
WW and C2 domain-containing protein-3 promoted EBSS-induced apoptosis through inhibiting autophagy in non-small cell lung cancer cells., PMID:32944332
Interaction of BACH2 with FUS promotes malignant progression of glioma cells via the TSLNC8-miR-10b-5p-WWC3 pathway., PMID:32892482
FRMPD1 activates the Hippo pathway via interaction with WWC3 to suppress the proliferation and invasiveness of lung cancer cells., PMID:31114375
Perinatal polychlorinated biphenyls and polychlorinated dibenzofurans exposure are associated with DNA methylation changes lasting to early adulthood: Findings from Yucheng second generation., PMID:30640082
SNP markers associated with body size and pelt length in American mink (Neovison vison)., PMID:30419805
WWC3 inhibits epithelial-mesenchymal transition of lung cancer by activating Hippo-YAP signaling., PMID:29780251
WWC3 inhibits intimal proliferation following vascular injury via the Hippo signaling pathway., PMID:29393412
WWC3 Inhibits Glioma Cell Proliferation Through Suppressing the Wnt/β-Catenin Signaling Pathway., PMID:29115863
WWC3 downregulation correlates with poor prognosis and inhibition of Hippo signaling in human gastric cancer., PMID:28652775
WWC3 regulates the Wnt and Hippo pathways via Dishevelled proteins and large tumour suppressor 1, to suppress lung cancer invasion and metastasis., PMID:28543074
Evolutionary and molecular facts link the WWC protein family to Hippo signaling., PMID:24682284
For research use only. Not for human or drug use.
