Catalog No.
YHJ79301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser267-His493
Predicted molecular weight
29.05 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UKU9
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Angiopoietin-related protein 2, ARP2, Angiopoietin-like protein 2, ANGPTL2
A novel EndMT inhibitor, xanthotoxin, attenuates non-alcoholic fatty liver disease by acting as TGFβR2 antagonist., PMID:40347928
Angiopoietin-like Protein 2 Expression Is Associated With Host Wasting-Related Poor Prognosis in Colorectal Cancer., PMID:40311354
Statement of Retraction: Knockdown of hypoxia-inducible factor 1-alpha (HIF1α) interferes with angiopoietin-like protein 2 (ANGPTL2) to attenuate high glucose-triggered hypoxia/reoxygenation injury in cardiomyocytes., PMID:40267142
Pathological Changes in Extracellular Matrix Composition Orchestrate the Fibrotic Feedback Loop Through Macrophage Activation in Dupuytren's Contracture., PMID:40243889
Serum Angptl2 and CyPA Levels in Acute Myocardial Infarction and In-Stent Restenosis After Percutaneous Coronary Intervention: A Single-Center Retrospective Case-Control Study., PMID:40196450
Adipocyte-secreted ANGPTL2 promotes hyperuricemia through inhibiting AKT/ABCG2 signaling., PMID:40180020
A novel photosensitive nanoprobe combined with CRISPR/Cas12a for dual signal amplification detection of ANGPTL2., PMID:40147084
Sexually dimorphic effects of angiopoietin-like 2 on energy metabolism and hypothalamic neuropeptide regulation., PMID:40133699
Colony-stimulating factor 3 and its receptor promote leukocyte immunoglobulin-like receptor B2 expression and ligands in gastric cancer., PMID:39958563
Prognostic value of serum angiopoietin-like protein 2 in patients with acute coronary syndrome., PMID:39702007
The Two Faces of Angiopoietin-Like Protein 2 in Cancer., PMID:39686837
Piperazine ferulate impact on diabetes-induced testicular dysfunction: unveiling genetic insights, MAPK/ERK/JNK pathways, and TGF-β signaling., PMID:39671097
Exploring the Association of VEGF-A and ANGPTL2 with the Prognosis of Non-proliferative and Proliferative Diabetic Retinopathy., PMID:39350883
Host ANGPTL2 establishes an immunosuppressive tumor microenvironment and resistance to immune checkpoint therapy., PMID:39321028
Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma., PMID:39255061
ANGPTL2: Is it a Novel Therapeutic Target Related to Tumor-Associated Macrophages in Esophageal Cancer?, PMID:39240396
Genome-wide variation study and inter-tissue communication analysis unveil regulatory mechanisms of egg-laying performance in chickens., PMID:39152103
Recombinant human amelogenin promotes wound healing by enhancing angiogenesis., PMID:39083979
Periodontitis promotes hepatocellular carcinoma in Stelic Animal model (STAM) mice., PMID:39080409
Angiopoietin-Like Protein 2 Expression in Tumor Cells Supports Tumor-Associated Macrophage-Induced Tumor Progression in Esophageal Cancer., PMID:38981990
Angiopoietin-like protein 2 inhibits thrombus formation., PMID:38880861
Panax Notoginseng Saponins Regulate Angiogenic Cytokines Through the PI3K/AKT/mTOR Signaling Pathway to Promote Fracture Healing in Ovariectomized Rats., PMID:38868856
Remodeling of tumor microenvironment by extracellular matrix protein 1a differentially regulates ovarian cancer metastasis., PMID:38849014
Novel biomarkers of preterm brain injury from blood transcriptome in sheep model of intrauterine asphyxia., PMID:38822135
Decreased Memory and Learning Ability Mediated by Bmal1/M1 Macrophages/Angptl2/Inflammatory Cytokine Pathway in Mice Exposed to Long-Term Blue Light Irradiation., PMID:38785563
ANGPTL2 knockdown induces autophagy to relieve alveolar macrophage pyroptosis by reducing LILRB2-mediated inhibition of TREM2., PMID:38758159
Urinary Proteomics and Outcomes in Heart Failure With Preserved Ejection Fraction., PMID:38639358
Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy., PMID:38467764
ILT4 facilitates angiogenesis in non-small cell lung cancer., PMID:38433526
Knockdown of ANGPTL2 promotes left ventricular systolic dysfunction by upregulation of NOX4 in mice., PMID:38426206
Aggressive fibromatosis-like tumour with ANGPTL2::USP6 fusion., PMID:38379048
Transcriptomic analyses and machine-learning methods reveal dysregulated key genes and potential pathogenesis in human osteoarthritic cartilage., PMID:38310924
High throughput functional profiling of genes at intraocular pressure loci reveals distinct networks for glaucoma., PMID:38272457
Leukocyte immunoglobulin-like receptor B2 overexpression as a promising therapeutic target and noninvasive screening biomarker for colorectal cancer., PMID:37899785
Endothelial-derived small extracellular vesicles support B-cell acute lymphoblastic leukemia development., PMID:37751067
ANGPTL2 promotes immune checkpoint inhibitor-related murine autoimmune myocarditis., PMID:37736764
Trio-based GWAS identifies novel associations and subtype-specific risk factors for cleft palate., PMID:37719664
ANGPTL2+cancer-associated fibroblasts and SPP1+macrophages are metastasis accelerators of colorectal cancer., PMID:37691929
ANGPTL2 aggravates LPS-induced septic cardiomyopathy via NLRP3-mediated inflammasome in a DUSP1-dependent pathway., PMID:37531825
ANGPTL2-mediated epigenetic repression of MHC-I in tumor cells accelerates tumor immune evasion., PMID:37452654
Angiopoietin-like 2 Protein and Hidradenitis Suppurativa: A New Biomarker for Disease Severity., PMID:37189824
Role of epicardial adipose tissue in human atrial fibrillation., PMID:37021018
Menstrual blood-derived stromal cells: insights into their secretome in acute hypoxia conditions., PMID:37016307
ANGPTL2 promotes VEGF-A synthesis in human lung cancer and facilitates lymphangiogenesis., PMID:36917086
ANGPTL2 Deletion Attenuates Neuroinflammation and Cognitive Dysfunction Induced by Isoflurane in Aged Mice through Modulating MAPK Pathway., PMID:36865085
ANGPTL2 binds MAG to efficiently enhance oligodendrocyte differentiation., PMID:36855057
Genetic and Epigenetic Regulation of the Innate Immune Response to Gout., PMID:36745138
Angiopoietin-like 2 is essential to aortic valve development in mice., PMID:36414704
ANGPTL2 aggravates doxorubicin-induced cardiotoxicity via inhibiting DUSP1 pathway., PMID:36107816
Tumor cell-derived ANGPTL2 promotes β-catenin-driven intestinal tumorigenesis., PMID:35831580
For research use only. Not for human or drug use.
