Catalog No.
YHJ78901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro1507-Arg1686
Predicted molecular weight
22.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UKP4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADAMTS-7, ADAMTS7, A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAM-TS7, COMPase, ADAM-TS 7
Chondrocyte fatty acid oxidation drives osteoarthritis via SOX9 degradation and epigenetic regulation., PMID:40425566
ADAMTS7, a target in atherosclerosis, cooperates with its homolog ADAMTS12 to protect against myxomatous valve degeneration., PMID:40115634
Association Between Plasma ADAMTS-7 Levels and Diastolic Dysfunction in Patients with Type 2 Diabetes Mellitus., PMID:39768861
Vaccination as a Promising Approach in Cardiovascular Risk Mitigation: Are We Ready to Embrace a Vaccine Strategy?, PMID:39766344
Six genetic variants are associated with cardiovascular disease independently from canonical risk factors: a new method to refine GWAS results based on the UKBiobank phenotype database., PMID:39704901
Construction of store-operated calcium entry-related gene signature for predicting prognosis and indicates immune microenvironment infiltration in stomach adenocarcinomas., PMID:39333689
ECM Microenvironment in Vascular Homeostasis: New Targets for Atherosclerosis., PMID:38984789
Systematic Review of Genetic Modifiers Associated with the Development and/or Progression of Nephropathy in Patients with Sickle Cell Disease., PMID:38791464
Circ_0104652 Promotes the Proliferation and Migration of ox-LDL-Stimulated Vascular Smooth Muscle Cells via Stabilizing ADAMTS7 and HMGB1., PMID:38536049
Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration., PMID:38528617
ADAMTS7 Promotes Smooth Muscle Foam Cell Expansion in Atherosclerosis., PMID:38463994
The Association of ADAMTS7 Gene Polymorphisms with the Risk of Coronary Artery Disease Occurrence and Cardiovascular Survival in the Polish Population: A Case-Control and a Prospective Cohort Study., PMID:38396951
BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor., PMID:38348661
ADAMTS-7 Modulates Atherosclerotic Plaque Formation by Degradation of TIMP-1., PMID:37675562
ADAMTS7: a Novel Therapeutic Target in Atherosclerosis., PMID:37354304
[Electroacupuncture improves motor function of rats with osteoarthritis by alleviating joint inflammation through the Wnt-7B/β-catenin signaling pathway]., PMID:37202195
Multimodal CRISPR perturbations of GWAS loci associated with coronary artery disease in vascular endothelial cells., PMID:36928188
Targeting ADAMTS-7: A Vaccination Against Atherosclerosis-and Its Complications?, PMID:36848412
The rs3825807 Polymorphism of ADAMTS7 as a Potential Genetic Marker for Myocardial Infarction in Slovenian Subjects with Type 2 Diabetes Mellitus., PMID:36833435
Non-Canonical WNT/Wnt5a Pathway Activity in Circulating Monocytes of Untreated Psoriatic Patients: An Exploratory Study of Its Association with Inflammatory Cytokines and Cardiovascular Risk Marker-ADAMTS7., PMID:36831113
ADAMTS7-Mediated Complement Factor H Degradation Potentiates Complement Activation to Contributing to Renal Injuries., PMID:36735376
Cleaving It All Behind: ADAMTS7 Degrades Factor H., PMID:36735370
ADAMTS-7 deficiency attenuates thoracic aortic aneurysm and dissection in mice., PMID:36662289
Peptide Vaccine Against ADAMTS-7 Ameliorates Atherosclerosis and Postinjury Neointima Hyperplasia., PMID:36562301
Genome-wide meta-analysis identifies new candidate genes for sickle cell disease nephropathy., PMID:36399516
Combining bioinformatics, network pharmacology and artificial intelligence to predict the mechanism of celastrol in the treatment of type 2 diabetes., PMID:36339449
Long non‑coding RNA LINC01960‑201 hinders decidualization of endometrial stromal cell in endometriosis: Relevance to endometrial receptivity., PMID:36281935
The Mechanism and Role of ADAMTS Protein Family in Osteoarthritis., PMID:35883515
ADAMTS7 Attenuates House Dust Mite-Induced Airway Inflammation and Th2 Immune Responses., PMID:35503474
Genome-wide pleiotropy analysis of coronary artery disease and pneumonia identifies shared immune pathways., PMID:35452290
TAILS Identifies Candidate Substrates and Biomarkers of ADAMTS7, a Therapeutic Protease Target in Coronary Artery Disease., PMID:35283288
Development of a fluorogenic ADAMTS-7 substrate., PMID:34587841
ADAMTS7 Knockdown in Context: Emerging Therapeutic Targets in Atherothrombosis., PMID:34351799
Coronary Disease Association With ADAMTS7 Is Due to Protease Activity., PMID:34176299
Investigating ADAMTS7 and ADAMTS12 levels in prediabetic and Type 2 diabetic patients., PMID:34169731
Age-associated changes in the transcriptomes of non-cultured adipose-derived stem cells from young and old mice assessed via single-cell transcriptome analysis., PMID:33237970
Association of polymorphisms in ADAMTS-7 gene with the susceptibility to coronary artery disease - a systematic review and meta-analysis., PMID:33122452
ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomas., PMID:32692461
The plasma peptides of sepsis., PMID:32636717
Elevated serum cartilage oligomeric matrix protein and the metalloproteinase-ADAMTS7 levels are associated with vascular calcification in maintenance hemodialysis patients., PMID:32441044
Hypomethylation of DNA promoter upregulates ADAMTS7 and contributes to HTR-8/SVneo and JEG-3 cells abnormalities in pre-eclampsia., PMID:32250736
ADATMS-7 regulates the focal adhesion kinase signaling and promotes invasiveness of trophoblasts in early pregnancy., PMID:32148246
Effect of a coronary-heart-disease-associated variant of ADAMTS7 on endothelial cell angiogenesis., PMID:32005000
Upregulation of miR‑423 improves autologous vein graft restenosis via targeting ADAMTS‑7., PMID:31894258
ADAMTS7 and ZC3HC1 Share Genetic Predisposition to Coronary Artery Disease and Large Artery Ischemic Stroke., PMID:31679296
Association between ADAMTS7 polymorphism and carotid artery plaque vulnerability., PMID:31651847
lncRNA/mRNA profiling of endometriosis rat uterine tissues during the implantation window., PMID:31638262
ADAMTS7: Recombinant Protein Expression and Purification., PMID:31463903
Genetic variants of ADAMTS7 confer risk for ischaemic stroke in the Chinese population., PMID:31460868
Identification of Phosphorylation Associated SNPs for Blood Pressure, Coronary Artery Disease and Stroke from Genome-wide Association Studies., PMID:31456518
For research use only. Not for human or drug use.
