Catalog No.
YHJ78201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro65-Pro328
Predicted molecular weight
56.67 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UJ71
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C-type lectin domain family 4 member K, CLEC4K, Langerin, CD207
Langerhans Cell Histiocytosis Presenting as a Limp in a Child: A Case Report., PMID:40443606
Langerhans cells infiltration in lymph nodes of patients with systemic lupus erythematosus., PMID:40228845
Plasma proteomics for risk prediction and identification of novel drug targets in systemic lupus erythematosus., PMID:39883569
Recognition of Staphylococcus aureus by the pattern recognition molecules langerin, mannan-binding lectin, and surfactant protein D: the influence of capsular polysaccharides and wall teichoic acid., PMID:39850879
Targeted delivery of cytotoxic proteins via lipid-based nanoparticles to primary Langerhans cells., PMID:39775685
BRAFV600E induces key features of LCH in iPSCs with cell type-specific phenotypes and drug responses., PMID:39630039
Monocytes give rise to Langerhans cells that preferentially migrate to lymph nodes at steady state., PMID:39541348
Langerhans Cell Histiocytosis or Acute Cellular Rejection?, PMID:39497510
A case of indeterminate cell histiocytosis with ETV3-NCOA2 translocation., PMID:39494947
Effect of bacterial fermentation on the ability of myofibrillar proteins to bind esters and its potential mechanism: Based on protein metabolism and structural changes., PMID:39427800
Integration of MUTZ-Langerhans cells into a 3D full-thickness skin equivalent and influences of serum reduction and undefined medium supplements on differentiation., PMID:39343070
Pulmonary Langerhans Cell Histiocytosis: Diagnosis in Bronchoalveolar Lavage Liquid-Based Cytology Samples., PMID:39025050
Anandamide modulation of monocyte-derived Langerhans cells: implications for immune homeostasis and skin inflammation., PMID:38979427
Langerhans cell histiocytosis mimicking acute dacryocystitis., PMID:38901610
The impact of irritant challenge on the skin barrier and myeloid-resident immune cells in women who are postmenopausal is modulated by hormone replacement therapy., PMID:38819239
Integrated Analysis of CD1A Immune Infiltration and Competing Endogenous RNA Networks in COAD., PMID:38751492
Pathologic characteristics of histiocytic and dendritic cell neoplasms., PMID:38713245
Langerhans cell histiocytosis: NACHO update on progress, chaos, and opportunity on the path to rational cures., PMID:38687639
Immunohistochemistry of the nasal cavity-associated lymphoid tissue in the dolphin (Stenella coeruleoalba, Meyen 1833)., PMID:38683022
Dendritic cell subpopulations in carcinoma ex-pleomorphic adenoma: A multicenter study., PMID:38655689
Increased AXLhigh myeloid cells as pathognomonic marker in Langerhans cell histiocytosis and Langerin expression dependence of mTOR inhibition., PMID:38575046
Primary Rosai-Dorfman disease of the central nervous system: A clinical, histological, and molecular appraisal., PMID:38548480
Secondary Sites of the C-type Lectin-Like Fold., PMID:38527187
Identification and characterization of stromal-like cells with CD207+/low CD1a+/low phenotype derived from histiocytic lesions - a perspective in vitro model for drug testing., PMID:38342891
Deep resolution of clinical, cellular and transcriptomic inflammatory markers of psoriasis over 52 weeks of interleukin-17A inhibition by secukinumab., PMID:38240024
Langerhans cell histiocytosis: promises and caveats of targeted therapies in high-risk and CNS disease., PMID:38066856
Dengue Virus Infects Human Skin Langerhans Cells through Langerin for Dissemination to Dendritic Cells., PMID:37979773
Single cell-resolved study of advanced murine MASH reveals a homeostatic pericyte signaling module., PMID:37972658
Successful treatment of Langerhans cell histiocytosis in an infant with vemurafenib: a case report and literature review., PMID:37941458
Mutant PIK3CA is a targetable driver alteration in histiocytic neoplasms., PMID:37874915
[Study the involvement of Langerin in mediating epicutaneous sensitization of atopic dermatitis-like mouse model]., PMID:37813655
Primary cutaneous Langerhans cell sarcoma without evident Birbeck granules: the importance of CD207/langerin positivity., PMID:37594347
Microenvironmental and cell intrinsic factors governing human cDC2 differentiation and monocyte reprogramming., PMID:37539048
Comparison of Immunohistochemical Markers in Oral Submucous Fibrosis and Oral Submucous Fibrosis Transformed to Oral Squamous Cell Carcinoma-A Systematic Review and Meta-Analysis., PMID:37511530
Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model., PMID:37454739
Clinical and prognostic features of Langerhans cell histiocytosis in adults., PMID:37364599
Modification with Conventional Surfactants to Improve a Lipid-Based Ionic-Liquid-Associated Transcutaneous Anticancer Vaccine., PMID:37049732
Emergence of SARS-CoV-2 spike protein at the vaccination site., PMID:36988249
Macrophages CD163+ and Factor XIIIa+ Provide a First-Line Defence against Proliferative Verrucous Leukoplakia Antigens., PMID:36982316
Case report: Targeting the PD-1 receptor and genetic mutations validated in primary histiocytic sarcoma with hemophagocytic lymphohistiocytosis., PMID:36969238
The discovery of a new type of innervation in lymphoid organs., PMID:36823776
Novel characterization of CXCR4 expressing cells in uninfected and herpes simplex virus-1 infected corneas., PMID:36813133
Targeting of SIRPα as a potential therapy for Langerhans cell histiocytosis., PMID:36788737
Novel ANKRD26 and PDGFRB gene mutations in pediatric case of non-Langerhans cell histiocytosis: Case report and literature review., PMID:36753059
Expression of tolerogenic dendritic cells in the small intestinal tissue of patients with celiac disease., PMID:36578401
Persistent post-COVID-19 smell loss is associated with immune cell infiltration and altered gene expression in olfactory epithelium., PMID:36542694
Consumption of fish oil high-fat diet induces murine hair loss via epidermal fatty acid binding protein in skin macrophages., PMID:36516778
TRPV4 Activation Increases the Expression of CD207 (Langerin) of Monocyte-Derived Langerhans Cells without Affecting their Maturation., PMID:36502939
Human Milk Oligosaccharide 2'-Fucosyllactose Inhibits Ligand Binding to C-Type Lectin DC-SIGN but Not to Langerin., PMID:36499067
The epidermal immune microenvironment plays a dominant role in psoriasis development, as revealed by mass cytometry., PMID:36348078
For research use only. Not for human or drug use.
