Catalog No.
YHJ76201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr24-Ser273
Predicted molecular weight
29.43 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UHF1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NOTCH4-like protein, Zneu1, Multiple EGF-like domains protein 7, Epidermal growth factor-like protein 7, MEGF7, EGFL7, VE-statin, EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Vascular endothelial statin
[Identification of endothelial cell key genes associated with pathogenesis and invasion of human venous malformations using single-nucleus RNA sequencing-based co-expression network analysis]., PMID:40176667
Regulation of hematopoietic stem cell (HSC) proliferation by Epithelial Growth Factor Like-7 (EGFL7)., PMID:39896615
EGFL7: An emerging biomarker with great therapeutic potential., PMID:39631508
Overexpression of EGFL7 promotes angiogenesis and nerve regeneration in peripheral nerve injury., PMID:39080995
Epidermal growth factor-like domain 7 drives brain lymphatic endothelial cell development through integrin αvβ3., PMID:39013903
Characterizing Common and Rare Variations in Nontraditional Glycemic Biomarkers Using Multivariate Approaches on Multiancestry ARIC Study., PMID:38869630
Structure, function, and recombinant production of EGFL7., PMID:38805373
Comparative transcriptomic analysis of circulating endothelial cells in sickle cell stroke., PMID:38386032
The mechanism of EGFL7 regulating neovascularization in diabetic retinopathy through the PI3K/AKT/VEGFA pathway., PMID:38307238
Diverse clinical presentations of pseudomyogenic hemangioendothelioma associated with EGFL7::FOSB fusion: a second case., PMID:38012540
Low EGFL7 expression is associated with high lymph node spread and invasion of lymphatic vessels in colorectal cancer., PMID:37957249
HLA-C*15:02 and epidermal growth factor receptor inhibitor-induced erosive pustular dermatosis of the scalp., PMID:37710038
Role of EGFL7 in human cancers: A review., PMID:37490307
Hepatocellular carcinoma cells remodel the pro-metastatic tumour microenvironment through recruitment and activation of fibroblasts via paracrine Egfl7 signaling., PMID:37480091
Localized Prox1 Regulates Aortic Valve Endothelial Cell Diversity and Extracellular Matrix Stratification in Mice., PMID:37381982
Epidermal growth factor-like 7 is a novel therapeutic target in mantle cell lymphoma., PMID:37209901
Characterization of epidermal growth factor-like domain 7 (EGFL7) expression in normal endometrium and in the endometrium of women with poor reproductive outcomes., PMID:37159518
Evaluation Of Epidermal Growth Factor-Like Domain (EGFL7) mRNA Expression and its Protein Level in Preeclampsia., PMID:36879940
EGFL7 loss correlates with increased VEGF-D expression, upregulating hippocampal adult neurogenesis and improving spatial learning and memory., PMID:36715759
EGFL7 Secreted By Human Bone Mesenchymal Stem Cells Promotes Osteoblast Differentiation Partly Via Downregulation Of Notch1-Hes1 Signaling Pathway., PMID:36609902
EGFL7 affects the migration of epidermal stem cells in refractory diabetic wounds by regulating Notch signaling pathway., PMID:36530156
EGFL7 drives the evolution of resistance to EGFR inhibitors in lung cancer by activating NOTCH signaling., PMID:36309484
Killing two birds with one stone: miR-126 involvement in both cancer and atherosclerosis., PMID:36111944
Diet X Gene Interactions Control Femoral Bone Adaptation to Low Dietary Calcium., PMID:36111202
Recombinant EGFL7 Mitigated Pressure Overload-Induced Cardiac Remodeling by Blocking PI3K γ /AKT/ NFκB Signaling in Macrophages., PMID:35721105
Single-cell RNA sequencing reveals differential expression of EGFL7 and VEGF in giant-cell tumor of bone and osteosarcoma., PMID:35695550
Impact of Activation of EGFL7 within Microenvironment of High Grade Ovarian Serous Carcinoma on Infiltration of CD4+ and CD8+ Lymphocytes., PMID:35630004
Targeting SMYD2 inhibits angiogenesis and increases the efficiency of apatinib by suppressing EGFL7 in colorectal cancer., PMID:35503397
The Polymorphism and Expression of EGFL7 and miR-126 Are Associated With NSCLC Susceptibility., PMID:35494025
EGFL7 and HIF-1a Expression on Human Trophoblast Placental by Rhodomyrtus tomentosa and Zanthoxylum acanthopodium., PMID:35234000
egfl6 expression in the pharyngeal pouch is dispensable for craniofacial development., PMID:34745432
EGF repeats of epidermal growth factor‑like domain 7 promote endothelial cell activation and tumor escape from the immune system., PMID:34738625
Targeting miR-126 in inv(16) acute myeloid leukemia inhibits leukemia development and leukemia stem cell maintenance., PMID:34686664
Relation among EGFL7, ITGB3, and KLF2 and their clinical implication in multiple myeloma patients: a prospective study., PMID:34635968
Circulating EGFL7 distinguishes between IUGR and PE: an observational case-control study., PMID:34504270
Comparative Transcriptional Analysis of Pulmonary Arterial Hypertension Associated With Three Different Diseases., PMID:34336829
Serum epidermal growth factor-like domain 7 serves as a novel diagnostic marker for early hepatocellular carcinoma., PMID:34217251
Epigenetic Silencing of MicroRNA-126 Promotes Cell Growth in Marek's Disease., PMID:34205549
Exosome-derived microRNAs in oral squamous cell carcinomas impact disease prognosis., PMID:34174519
Epigenetic down-regulation of microRNA-126 in scleroderma endothelial cells is associated with impaired responses to VEGF and defective angiogenesis., PMID:34137496
An increase in elastogenic components in the placental villi of women with chronic venous disease during pregnancy is associated with decreased EGFL7 expression level., PMID:34080027
Epidermal growth factor-like domain 7 regulates breast cancer cell proliferation and vascular endothelial growth factor expression via the p38MAPK signaling pathway., PMID:34017420
The Multifaceted Roles of EGFL7 in Cancer and Drug Resistance., PMID:33804387
Diagnostic Utility of IGF2BP1 and Its Targets as Potential Biomarkers in ETV6-RUNX1 Positive B-Cell Acute Lymphoblastic Leukemia., PMID:33708624
EGFL7 as a novel therapeutic candidate regulates cell invasion and anoikis in colorectal cancer through PI3K/AKT signaling pathway., PMID:33635474
Novel EGFL7-FOSB fusion in pseudomyogenic haemangioendothelioma with widely metastatic disease., PMID:33550637
Suppression of lncRNA HOTAIR alleviates RCC angiogenesis through regulating miR-126/EGFL7 axis., PMID:33502949
Evaluation of the prognostic potential of EGFL7 in pilocytic astrocytomas., PMID:33191640
Proteomics identifies EGF-like domain multiple 7 as a potential therapeutic target for epidermal growth factor receptor-positive glioma., PMID:32888253
Treatment of pregnancies complicated by intrauterine growth restriction with nitric oxide donors increases placental expression of Epidermal Growth Factor-Like Domain 7 and improves fetal growth: A pilot study., PMID:32784003
For research use only. Not for human or drug use.
