Catalog No.
YHJ74601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu34-Ser981
Predicted molecular weight
111.35 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UEF7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Klotho, KL
Murine maternal microbiome modifies adverse effects of protein undernutrition on offspring neurobehaviour., PMID:40514563
Association between serum Klotho and all-cause mortality in postmenopausal women: a prospective population-based cohort analysis from NHANES 2007-2016., PMID:40511875
Plasma Proteomics Reveals Dysregulated Pathways Across the Spectrum LMNA Cardiomyopathy., PMID:40509996
Age-Related Dysregulation of α5β1 and αvβ3 Integrin Activity Alters Contractile Properties of Trabecular Meshwork Cells., PMID:40488712
First-in-human evaluation of a no-alpha interleukin-2 mutein: safety and preliminary pharmacodynamic and clinical effect., PMID:40486521
Glucocorticoid treatment in early rheumatoid arthritis is independently associated with increased PCSK9 levels: data from a randomised controlled trial., PMID:40480650
Recovery and protection of photo-damaged hairs with keratin-encapsulated cationic liposomes., PMID:40476308
LC-MS/MS proteomics identifies plasma proteins related to cognition over 9-year follow-up., PMID:40469059
A complete map of human cytosolic degrons and their relevance for disease., PMID:40463067
Modulation of microglial phagocytosis via the GAS6-MERTK pathway regulates pathological angiogenesis in the mouse oxygen-induced retinopathy model., PMID:40456730
Harnessing synaptic vesicle release and recycling with antibody shuttle for targeted delivery of therapeutics to neurons., PMID:40454418
Study on the Predictive Value of Inflammatory Factors and Biomarkers in Synovial Fluid for Disease Progression in Knee Osteoarthritis Patients., PMID:40452194
Comparison between endovascular and surgical treatment of acute arterial occlusive mesenteric ischemia., PMID:40452055
Role of blood Krebs von Lungen-6 in predicting acute exacerbation in patients with idiopathic pulmonary fibrosis., PMID:40446067
Multiomic Landscape of Extracellular Vesicles in Human Carotid Atherosclerotic Plaque Reveals Endothelial Communication Networks., PMID:40438929
Serum alpha-klotho levels associate with bone mineral density in chronic kidney disease patients from NHANES 2011 to 2016., PMID:40436995
Experimental Infection of Ferrets with Bartonella henselae: In Search of a Novel Animal Model for Zoonotic Bartonellosis., PMID:40430742
Bayesian Integration of Bronchoalveolar Lavage miRNAs and KL-6 in Progressive Pulmonary Fibrosis Diagnosis., PMID:40428250
The Role of Klotho in Oral and Maxillofacial Diseases: Mechanisms and Research Progress., PMID:40427517
Super-resolution imaging of native fluorescent photoreceptors in chytrid fungal eyes., PMID:40425855
Prediction of coronary heart disease based on klotho levels using machine learning., PMID:40425693
Peptide-based biosensor for real-time monitoring of protease biomarker activity using multi-parametric surface plasmon resonance spectroscopy., PMID:40424862
Klotho protein: a multifaceted regulator in aging and cancer dynamics., PMID:40423846
Fusobacterium nucleatum enhances cholesterol biosynthesis in colorectal cancer via miR-130a-3p-mediated AMPK inhibition, a process counteracted by butyrate., PMID:40414519
Identification of Age- and Cataract-Related Changes in High-Density Lens Protein Aggregates., PMID:40408093
Efficacy, safety, and insulin-like growth factor I of weekly somapacitan in children with growth hormone deficiency: 3-year results from REAL4., PMID:40400262
Does the IL-6/KL-6 ratio distinguish different phenotypes in COVID-19 Acute Respiratory Distress Syndrome? An observational study stemmed from prospectively derived clinical, biological, and computed tomographic data., PMID:40397955
Correction: A method for creating in-frame insertions of fluorescent proteins in non-model gram-negative bacteria., PMID:40397238
Sex-specific association between serum α-klotho levels and sleep disturbances in the elderly: a cross-sectional study., PMID:40394689
Proteolytic degradation of Beta-Ig H3 (βigH3/TGFBI) can be quantified non-invasively in serum and predicts prognosis in patients with advanced pancreatic ductal adenocarcinoma., PMID:40394523
A novel SUN1-ALLAN complex coordinates segregation of the bipartite MTOC across the nuclear envelope during rapid closed mitosis in Plasmodium berghei., PMID:40392232
Association of serum Klotho concentrations with abdominal obesity among middle-aged adults in the US: Evidence from NHANES 2011-2016., PMID:40381255
Effects of Janus kinase inhibitors in adults admitted to hospital due to COVID-19: a systematic review and individual participant data meta-analysis of randomised clinical trials., PMID:40378861
The impact of breast radiotherapy on the tumor genome and immune ecosystem., PMID:40378044
Associations of weight-adjusted-waist index and systemic immune-inflammatory index with sKlotho: evidence from the NHANES 2007-2016., PMID:40375945
Acute infectious mononucleosis generates persistent, functional EBNA-1 antibodies with high cross-reactivity to alpha-crystalline beta., PMID:40372913
[Anti-aging klotho protein. Associations with sleep patterns in obstructive sleep apnea: A pilot study]., PMID:40371865
Hierarchy in regulator interactions with distant transcriptional activation domains empowers rheostatic regulation., PMID:40371733
Klotho plasma levels are an independent predictorof mortality in women with acute coronary syndrome., PMID:40369094
Anti-aging protein α-Klotho is potential for reducing comorbidity risk of cardiometabolic diseases in vulnerable populations and enhancing long-term prognosis., PMID:40369033
Insights into interstitial lung disease pathogenesis., PMID:40365095
Shared and Distinctive Inflammation-Related Protein Profiling in Idiopathic Inflammatory Myopathy with/without Anti-MDA5 Autoantibodies., PMID:40357378
Urinary Extracellular Vesicle Analysis Reveals Early Signs of Kidney Inflammation and Damage in Single Ventricle Paediatric Patients After Fontan Operation., PMID:40356857
ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression., PMID:40355545
Hyperglycemia-induced α-Klotho downregulation impairs mitophagy and promotes placental dysfunction in T2DM pregnancies., PMID:40349475
Epitopes targeted by autoantibodies in presymptomatic individuals predict early rheumatoid arthritis., PMID:40348635
Proteomic Analysis of Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Clinical Trial., PMID:40340372
Soluble alpha klotho-impact of biological variables and reference intervals for adults., PMID:40338072
The positive relationship between the Alternative Healthy Diet Index and serum klotho levels: A cross-sectional analysis in middle-to-older Americans., PMID:40333908
Carboxymethyl Chitosan Capped Bimetallic Nanoparticles Entrapped in Theranostic Nanofibers: Antimicrobial Peptide Coating, In Vitro, In Vivo Characterization for MDR Microbial Infection and Photoacoustic/Optical Imaging., PMID:40332166
For research use only. Not for human or drug use.
