Catalog No.
YHJ73701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys34-Ile259
Predicted molecular weight
27.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UBU2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dkk-2, hDkk-2, Dickkopf-related protein 2, DKK2, Dickkopf-2
Fusobacterium mortiferum and its metabolite 5-aminovaleric acid promote the development of colorectal cancer in obese individuals through Wnt/β-catenin pathway by DKK2., PMID:40340623
Potential drug targets for ovarian cancer identified through Mendelian randomization and colocalization analysis., PMID:39972314
Downregulated DKK2 may serve as a molecular mechanism of high-fat diet-induced myocardial injury via Wnt/β-catenin pathway., PMID:39667489
Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties., PMID:39535280
Dickkopf-related Protein 2 Promotes Hair Growth by Upregulating the Wnt/β-catenin Signaling Pathway in Human Dermal Papilla Cells., PMID:39343756
Noncoding RNA regulates the expression of Krm1 and Dkk2 to synergistically affect aortic valve lesions., PMID:38945954
Spatial Multi-omics Reveals the Role of the Wnt Modulator, Dkk2, in Palatogenesis'., PMID:38910391
The assessment of Dickkopf-1 and Dickkopf-2 protein concentration in different subtypes of non-small cell lung cancer subtypes., PMID:38800531
DKK2 promotes the progression of oral squamous cell carcinoma through the PI3K/AKT signaling pathway., PMID:38795388
Metastasis of colon cancer requires Dickkopf-2 to generate cancer cells with Paneth cell properties., PMID:38659853
Molecular and Spatial Signatures of Mouse Embryonic Endothelial Cells at Single-Cell Resolution., PMID:38348657
The Multifaceted Role of Human Dickkopf-3 (DKK-3) in Development, Immune Modulation and Cancer., PMID:38201279
Molecular Evolution and Protein Structure Variation of Dkk Family., PMID:37895211
miR-29a-SIRT1-Wnt/β-Catenin Axis Regulates Tumor Progression and Survival in Hepatocellular Carcinoma., PMID:37776468
Frizzled 6 mutation regulates reserpine-induced depression-like behavior and Wnt signaling pathway in mice., PMID:37597646
Genome-wide DNA methylation and transcriptome expression profiles of peripheral blood mononuclear cells in patients with systemic sclerosis with interstitial lung disease., PMID:37587067
Promoter methylation analysis of DKK2 may be a potential biomarker for early detection of cervical cancer., PMID:37551167
ARHGAP9 knockdown promotes lung adenocarcinoma metastasis by activating Wnt/β-catenin signaling pathway via suppressing DKK2., PMID:37454937
Transcriptomic and Proteomic Changes Driving Pulmonary Fibrosis Resolution in Young and Old Mice., PMID:37411041
Transcriptome analysis to identify candidate genes related to mammary gland development of Bactrian camel (Camelus bactrianus)., PMID:37342620
The effect of 1,25-dihydroxyvitamin D3 on the Wnt signaling pathway in bovine intestinal epithelial cells is mediated by the DKK2 (dickkopf2) Wnt antagonist., PMID:37149202
Linoleic acid-induced ANGPTL4 inhibits C2C12 skeletal muscle differentiation by suppressing Wnt/β-catenin., PMID:36963729
Potential biomarkers of aortic dissection based on expression network analysis., PMID:36959563
Characterization of Histone Modifications in Late-Stage Rotator Cuff Tendinopathy., PMID:36833423
Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis., PMID:36747258
Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer's Disease Brains and Mouse Neurodegeneration Models., PMID:36599670
Construction of Fzd6Q152E mice through CRISPR/Cas9 technology and their reproduction and identification., PMID:35980530
METTL3 mediates Ang-II-induced cardiac hypertrophy through accelerating pri-miR-221/222 maturation in an m6A-dependent manner., PMID:35836108
HCV Core protein represses DKK3 expression via epigenetic silencing and activates the Wnt/β-catenin signaling pathway during the progression of HCC., PMID:35768685
Genome-Wide Placental Gene Methylations in Gestational Diabetes Mellitus, Fetal Growth and Metabolic Health Biomarkers in Cord Blood., PMID:35721735
Maternal binge alcohol consumption leads to distinctive acute perturbations in embryonic cardiac gene expression profiles., PMID:35692084
Androgen/Wnt/β-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum., PMID:35318743
circCELF1 Inhibits Myocardial Fibrosis by Regulating the Expression of DKK2 Through FTO/m6A and miR-636., PMID:35132536
MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity., PMID:35114852
Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer., PMID:35101137
Understanding of mouse and human bladder at single-cell resolution: integrated analysis of trajectory and cell-cell interactive networks based on multiple scRNA-seq datasets., PMID:34951074
miR-21-5p and canonical Wnt signaling pathway promote osteoblast function through a feed-forward loop induced by fluoride., PMID:34942272
Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation., PMID:34845225
Dickkopf signaling, beyond Wnt-mediated biology., PMID:34801396
Mesenchymal Stem Cell-Derived Extracellular Vesicles Inhibit Osteoporosis via MicroRNA-27a-Induced Inhibition of DKK2-Mediated Wnt/β-Catenin Pathway., PMID:34676493
Exosomal miR-27a-3p derived from tumor-associated macrophage suppresses propranolol sensitivity in infantile hemangioma., PMID:34634611
Potential genes and pathways associated with heterotopic ossification derived from analyses of gene expression profiles., PMID:34389038
CircCNIH4 inhibits gastric cancer progression via regulating DKK2 and FRZB expression and Wnt/β-catenin pathway., PMID:34364402
A comprehensive meta-analysis and a case-control study give insights into genetic susceptibility of lung cancer and subgroups., PMID:34272429
Toxicity of thioacetamide and protective effects of quercetin in zebrafish (Danio rerio) larvae., PMID:34227734
Long Noncoding RNA GAS5 in Breast Cancer: Epigenetic Mechanisms and Biological Functions., PMID:34202777
Dickkopf-2 knockdown protects against classic macrophage polarization and lipid loading by activation of Wnt/β-catenin signaling., PMID:34030936
Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1., PMID:33997693
RNAM EXPRESSION AND DNA METHYLATION OF DKK2 GENE IN COLORECTAL CÂNCER., PMID:33909798
G Protein-Coupled Estrogen Receptor Correlates With Dkk2 Expression and Has Prognostic Impact in Ovarian Cancer Patients., PMID:33679613
For research use only. Not for human or drug use.
