Catalog No.
YHJ73201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala37-Ile350
Predicted molecular weight
37.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9UBP4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dkk-3, Dickkopf-related protein 3, Dickkopf-3, hDkk-3, DKK3, REIC
ZBED6 Knockout Prevents Ageing- and Dexamethasone-Induced Muscle Atrophy via Dkk3 in Pig and Mice., PMID:40464206
Crocin drives intestinal microbiota variation in a rat model of Alzheimer's disease by reducing DKK3 expression., PMID:40419073
Urine choline oxidation metabolites predict chronic kidney disease progression in patients with type 2 diabetes., PMID:40359238
Markers of Kidney Injury: Proenkephalin A and Uromodulin, but Not Dickkopf-3, Are Elevated in Patients After Hematopoietic Stem Cell Transplantation., PMID:40332103
Causal roles of lipids and mediating proteins in diabetic retinopathy: insights from metabolomic and proteomic Mendelian randomization., PMID:40287778
Mechanism of Nano-Microplastics Exposure-Induced Myocardial Fibrosis: DKK3-Mediated Mitophagy Dysfunction and Pyroptosis., PMID:40262053
DKK3 and SERPINB5 as novel serum biomarkers for gastric cancer: facilitating the development of risk prediction models for gastric cancer., PMID:40231256
Targeting DKK3 to remodel tumor immune microenvironment and enhance cancer immunotherapy., PMID:40205566
Mechanistic insights into the neuroprotective effects of low-intensity transcranial ultrasound stimulation in post-cardiac arrest brain injury: Modulation of the Piezo1-Dkk3/PI3K-Akt pathway., PMID:40118226
Development of a multiple urinary biomarker model to predict the tubulointerstitial fibrosis area in patients with primary IgA Nephropathy., PMID:40114119
Influencing factors and quality traits of pigeon meat: A systematic review., PMID:40068574
Advances and insights for DKK3 in non-cancerous diseases: a systematic review., PMID:39959827
MicroRNA-27a transfected dental pulp stem cells undergo odonto/osteogenic differentiation via targeting DKK3 and SOSTDC1 in Wnt/BMP signaling in vitro and enhance bone formation in vivo., PMID:39956898
Serum Dickkopf-3 as a biomarker for predicting acute kidney injury in postoperative intensive care patients., PMID:39912573
Dkk3 inhibits the aggressiveness and mitigates chemoresistance through low lipid droplet formation in gastric cancer: A biomarker and gene therapy target., PMID:39908801
Urinary Dickkopf-related protein 3 as a novel biomarker for kidney function decline in children with Alport syndrome., PMID:39904897
Myokines: metabolic regulation in obesity and type 2 diabetes., PMID:39872377
Associations between skeletal muscle mass and elevated blood pressure are independent of body fat: a cross-sectional study in young adult women of African ancestry., PMID:39817427
Urinary Dickkopf-3 Reflects Disease Severity and Predicts Short-Term Kidney Function Decline in Renal Ciliopathies., PMID:39810774
Diagnostic Accuracy of a Blood-Based Biomarker Panel for Colorectal Cancer Detection: A Pilot Study., PMID:39766076
miR-151a-5p predicts severity of diabetic retinopathy and protects from retinal cell injury by inactivating MAPK signaling via DKK3., PMID:39701171
WIF1 and DKK3 in prostate cancer: from molecular pathways to therapeutic targets: a narrative review., PMID:39698576
YTHDF2 contributes to psoriasis by promoting proliferation and inflammatory response through regulation of the Wnt signaling pathway., PMID:39608173
Chidamide and venetoclax synergistically regulate the Wnt/β-catenin pathway by MYCN/DKK3 in B-ALL., PMID:39607486
Urinary Dickkopf-3 as a Potential Marker for Estimated Glomerular Filtration Rate Decline in Patients With Heart Failure., PMID:39604022
DKK3 as a diagnostic marker and potential therapeutic target for sarcopenia in chronic obstructive pulmonary disease., PMID:39571512
Urinary dickkopf-3 as a predictor for postoperative acute kidney injury in the intensive care unit., PMID:39561890
Potential Drug Targets for Diabetic Retinopathy Identified Through Mendelian Randomization Analysis., PMID:39541108
Epithelial splicing regulatory protein 1 promotes peritoneal dissemination of ovarian cancer by inducing the formation of circular RNAs modulating epithelial plasticity., PMID:39461579
The effects of therapeutic hypothermia on the expression of DKK3 and myocardial ischemia-reperfusion injury., PMID:39423658
DKK3 promotes adipogenic differentiation of stem cells by inhibiting Wnt/β-catenin signaling pathway related gene expression and mitochondrial autophagy function., PMID:39316979
Deceased donor urinary Dickkopf-3 associates with future allograft function following kidney transplantation., PMID:39303796
Peritoneal and renal DKK3 clearance in peritoneal dialysis., PMID:39179976
WTAP and METTL14 regulate the m6A modification of DKK3 in renal tubular epithelial cells of diabetic nephropathy., PMID:39151294
Characterization of Inflammation/Immune-, Acute Phase-, Extracellular Matrix-, Adhesion-, and Serine Protease-Related Proteins in the Amniotic Fluid of Women With Early Preterm Prelabor Rupture of Membranes., PMID:39113666
[FAPI-PET-CT for quantification of the tissue response in rheumatic diseases]., PMID:39031195
Study on the role of MYCN in retinoblastoma by inhibiting p53 and activating wnt/βcatenin/Fra-1 signaling pathway by reducing DKK3., PMID:39003564
SFRP4 protein expression is reduced in high grade astrocytomas which is not caused by the methylation of its promoter., PMID:38993819
MiR-98-3p alleviates lipopolysaccharide-induced pulmonary microvascular endothelial barrier dysfunction by targeting DKK3 in sepsis-induced acute lung injury., PMID:38945840
Transcriptome profiling of fast/glycolytic and slow/oxidative muscle fibers in aging and obesity., PMID:38942747
The prognostic value of Dickkopf-3 (Dkk3), TGFB1 and ECM-1 in prostate cancer., PMID:38855324
Urinary Dickkopf 3 Is Not an Independent Risk Factor in a Cohort of Kidney Transplant Recipients and Living Donors., PMID:38791413
DKK3 promotes renal fibrosis by increasing MFF-mediated mitochondrial dysfunction in Wnt/β-catenin pathway-dependent manner., PMID:38682264
Predictive value of glycoprotein DKK3 for early neurological deterioration after ischemic stroke., PMID:38678874
DKK3 Expression in Glioblastoma: Correlations with Biomolecular Markers., PMID:38612910
High dose statin treatment reduces circulating Dickkopf-1 following acute myocardial infarction., PMID:38604450
Whole-Genome Identification and Characterization of the DKK Gene Family and Its Transcription Profiles: An Analysis of the Chinese Soft-Shell Turtle (Pelodiscus sinensis)., PMID:38540029
Combined DNA Methylation and Gastric Microbiome Marker Predicts Helicobacter pylori-Negative Gastric Cancer., PMID:38509701
Association of Urinary Dickkopf-3 Levels with Cardiovascular Events and Kidney Disease Progression in Systolic Blood Pressure Intervention Trial., PMID:38472135
Identification of microRNA-mRNA Regulatory Networks with Therapeutic Values in Alzheimer's Disease by Bioinformatics Analysis., PMID:38427479
For research use only. Not for human or drug use.
