Catalog No.
YHJ67801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val472-Ser735
Predicted molecular weight
31.02 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NUT2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-binding cassette sub-family B member 8, mitochondrial, Mitochondrial potassium channel ATP-binding subunit, Mitochondrial sulfonylurea-receptor, ABCB8, Mitochondrial ATP-binding cassette 1, MITOSUR, MABC1, M-ABC1
Conformational equilibrium of an ABC transporter analyzed by luminescence resonance energy transfer., PMID:39973007
Cerebral ischemic injury impairs autophagy and exacerbates cognitive impairment in APP/PS1 mice., PMID:39522311
Uncovering novel drug targets for bipolar disorder: a Mendelian randomization analysis of brain, cerebrospinal fluid, and plasma proteomes., PMID:38720515
Protective Role of Dioscin against Doxorubicin-Induced Chronic Cardiotoxicity: Insights from Nrf2-GPX4 Axis-Mediated Cardiac Ferroptosis., PMID:38672439
Multi-omics analysis reveals critical metabolic regulators in bladder cancer., PMID:37882969
Integrative proteome and metabolome analyses reveal molecular basis underlying growth and nutrient composition in the Pacific oyster, Crassostrea gigas., PMID:37838097
Competitive interaction between ATP and GTP regulates mitochondrial ATP-sensitive potassium channels., PMID:37244398
Identification and Validation of Prognostic Related Hallmark ATP-Binding Cassette Transporters Associated With Immune Cell Infiltration Patterns in Thyroid Carcinoma., PMID:35837087
Banxia-Houpu decoction diminishes iron toxicity damage in heart induced by chronic intermittent hypoxia., PMID:35286247
A Survey of Enhanced Cold Tolerance and Low-Temperature-Induced Anthocyanin Accumulation in a Novel Zoysia japonica Biotype., PMID:35161412
Pharmacological and molecular docking studies reveal that glibenclamide competitively inhibits diazoxide-induced mitochondrial ATP-sensitive potassium channel activation and pharmacological preconditioning., PMID:34324857
ABCG1 and ABCG4 as key transporters in the development of pulmonary alveolar proteinosis by nanoparticles., PMID:34256330
Cryo-EM structure of human ABCB8 transporter in nucleotide binding state., PMID:33872987
Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8., PMID:33835027
Comprehensive Analysis of the ATP-binding Cassette Subfamily B Across Renal Cancers Identifies ABCB8 Overexpression in Phenotypically Aggressive Clear Cell Renal Cell Carcinoma., PMID:33011150
Signalling, Metabolic Pathways and Iron Homeostasis in Endothelial Cells in Health, Atherosclerosis and Alzheimer's Disease., PMID:32911833
Superparamagnetic iron oxide nanoparticles promote ferroptosis of ischemic cardiomyocytes., PMID:32780538
Multiple ATP-binding cassette transporters genes are involved in thiamethoxam resistance in Aphis gossypii glover., PMID:32527432
Identification and Characterization of a Transcribed Distal Enhancer Involved in Cardiac Kcnh2 Regulation., PMID:31484079
Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress., PMID:30623799
Exposure to amitraz, fipronil and permethrin affects cell viability and ABC transporter gene expression in an Ixodes ricinus cell line., PMID:30064465
Growth Hormone Receptor Knockdown Sensitizes Human Melanoma Cells to Chemotherapy by Attenuating Expression of ABC Drug Efflux Pumps., PMID:28293855
Impact of TET2 deficiency on iron metabolism in erythroblasts., PMID:28167288
Definition of mutations in polyautoimmunity., PMID:27209085
Daunorubicin Down-Regulates the Expression of Stem Cell Markers and Factors Involved in Stem Cell Migration and Homing in Rat Heart in Subchronic but not Acute Cardiomyopathy., PMID:27090888
Evaluation of the in vitro expression of ATP binding-cassette (ABC) proteins in an Ixodes ricinus cell line exposed to ivermectin., PMID:27090214
A longitudinal study of ABC transporter expression in canine multicentric lymphoma., PMID:25475167
PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis., PMID:25063848
Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation., PMID:24382354
Profiling of ABC transporters during active ulcerative colitis and in vitro effect of inflammatory modulators., PMID:23512405
Mitochondrial ABC transporters function: the role of ABCB10 (ABC-me) as a novel player in cellular handling of reactive oxygen species., PMID:22884976
Shifting the paradigm: the putative mitochondrial protein ABCB6 resides in the lysosomes of cells and in the plasma membrane of erythrocytes., PMID:22655043
Disruption of ATP-binding cassette B8 in mice leads to cardiomyopathy through a decrease in mitochondrial iron export., PMID:22375032
Mithramycin A suppresses expression of the human melanoma-associated gene ABCB8., PMID:21046154
Involvement of ABC transporters in melanogenesis and the development of multidrug resistance of melanoma., PMID:19725928
Mitochondrial ABC proteins in health and disease., PMID:19248758
Exclusion of ABCB8 and ABCB10 as cancer candidate genes in acute myeloid leukemia., PMID:19151771
ABCB8 mediates doxorubicin resistance in melanoma cells by protecting the mitochondrial genome., PMID:19147539
Intracellular peptide transporters in human--compartmentalization of the "peptidome"., PMID:16710701
Molecular cloning of several rat ABC transporters including a new ABC transporter, Abcb8, and their expression in rat testis., PMID:16390497
Alteration in copy numbers of genes as a mechanism for acquired drug resistance., PMID:14973057
Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population., PMID:11829140
For research use only. Not for human or drug use.
