Catalog No.
YHJ67001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala22-Asn199
Predicted molecular weight
46.30 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NS71
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Gastrokine-1, Protein CA11, AMP18, AMP-18, GKN1, CA11, 18 kDa antrum mucosa protein
Promising protein biomarkers for early gastric cancer: clinical performance of combined detection., PMID:40305430
Vitamin D3 mitigates aspirin-induced gastric injury by modulating gastrokines, E-cadherin, and inhibiting NLRP3 and NF-κB/MMP-9 signaling pathway., PMID:39823708
Gastrokine 1 transferred by gastric cancer exosomes inhibits growth and invasion of gastric cancer cells in vitro and in vivo., PMID:39524138
IL-33 Accelerates Chronic Atrophic Gastritis through AMPK-ULK1 Axis Mediated Autolysosomal Degradation of GKN1., PMID:38617533
[Screening of differentially expressed genes in gastric cancer based on GEO database and function and pathway enrichment analysis]., PMID:38597453
Significance of Gastrokine-1 Polymorphism Rs4254535 as a Prognostic Marker and its Association with Clinical Characteristics in Chinese Lung Cancer Patients., PMID:38250608
Expression Profiling along the Murine Intestine: Different Mucosal Protection Systems and Alterations in Tff1-Deficient Animals., PMID:37628863
Anoikis-Related Gene Signature for Prognostication of Pancreatic Adenocarcinoma: A Multi-Omics Exploration and Verification Study., PMID:37370756
AKR1B10 regulates M2 macrophage polarization to promote the malignant phenotype of gastric cancer., PMID:37039038
Helicobacter pylori shows tropism to gastric differentiated pit cells dependent on urea chemotaxis., PMID:36198679
miR-548d-3p inhibits the invasion and migration of gastric cancer cells by targeting GKN1., PMID:35666636
De novo expression of gastrokines in pancreatic precursor lesions impede the development of pancreatic cancer., PMID:35082384
Gastrokine-1, an anti-amyloidogenic protein secreted by the stomach, regulates diet-induced obesity., PMID:33947892
Coordinate expression loss of GKN1 and GKN2 in gastric cancer via impairment of a glucocorticoid-responsive enhancer., PMID:32538140
Uptake and tumor-suppressive pathways of exosome-associated GKN1 protein in gastric epithelial cells., PMID:32291710
Women with chronic follicular gastritis positive for Helicobacter pylori express lower levels of GKN1., PMID:32086651
Helicobacter pylori inhibits GKN1 expression via the CagA/p-ERK/AUF1 pathway., PMID:31657090
GKN1 expression in gastric cancer cells is negatively regulated by miR-544a., PMID:31509760
The diagnostic value of serum gastrokine 1 (GKN1) protein in gastric cancer., PMID:31376239
Regulation of GKN1 expression in gastric carcinogenesis: A problem to resolve (Review)., PMID:31322194
Keratin 14-high subpopulation mediates lung cancer metastasis potentially through Gkn1 upregulation., PMID:31320708
Targeting cholecystokinin-2 receptor for pancreatic cancer chemoprevention., PMID:31313401
[Expressions of Sry-related High Mobility Group Box 9 and Gastrokine-1 in Gastric Cancer and Their Relationships with Prognosis]., PMID:31282324
The role and diagnostic potential of gastrokine 1 in gastric cancer., PMID:30881118
Gastrokine 1 protein is a potential theragnostic target for gastric cancer., PMID:29704153
Spatiotemporally Controlled Ablation of Klf5 Results in Dysregulated Epithelial Homeostasis in Adult Mouse Corneas., PMID:28910443
Role of human GKN1 on APP processing in gastric cancer., PMID:28214529
Epigenetic alterations of gastrokine 1 gene expression in gastric cancer., PMID:28129645
The E3 ligase UBR5 regulates gastric cancer cell growth by destabilizing the tumor suppressor GKN1., PMID:27590582
Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer., PMID:27452910
Gastrokine 1 inhibits gastric cancer cell migration and invasion by downregulating RhoA expression., PMID:27250838
A Novel Peptide for Simultaneously Enhanced Treatment of Head and Neck Cancer and Mitigation of Oral Mucositis., PMID:27049860
AMP18 interacts with the anion exchanger SLC26A3 and enhances its expression in gastric cancer cells., PMID:26700142
NKX6.3 controls gastric differentiation and tumorigenesis., PMID:26314965
Antrum Mucosal Protein-18 Peptide Targets Tight Junctions to Protect and Heal Barrier Structure and Function in Models of Inflammatory Bowel Disease., PMID:26197453
Trophoblast expression dynamics of the tumor suppressor gene gastrokine 2., PMID:26070363
Ectopic expression of gastrokine 1 in gastric cancer cells up-regulates tight and adherens junction proteins network., PMID:26008777
Polymorphisms in C-reactive protein and Glypican-5 are associated with lung cancer risk and Gartrokine-1 influences Cisplatin-based chemotherapy response in a Chinese Han population., PMID:25999661
AMP-18 Targets p21 to Maintain Epithelial Homeostasis., PMID:25919700
Gastrokine 1 inhibits gastrin-induced cell proliferation., PMID:25752269
GKN1 inhibits cell invasion in gastric cancer by inactivating the NF-kappaB pathway., PMID:25725220
Decreased expression of gastrokine 1 in gastric mucosa of gastric cancer patients., PMID:25469040
Gastrokine 1 induces senescence and apoptosis through regulating telomere length in gastric cancer., PMID:25344918
The role of gastrokine 1 in gastric cancer., PMID:25328759
Gastrokine 1 inhibits the carcinogenic potentials of Helicobacter pylori CagA., PMID:25239641
Anti-amyloidogenic property of human gastrokine 1., PMID:25139219
EBNA1 binding and epigenetic regulation of gastrokine tumor suppressor genes in gastric carcinoma cells., PMID:24460791
Discovery of tumor markers for gastric cancer by proteomics., PMID:24404153
GKN2 contributes to the homeostasis of gastric mucosa by inhibiting GKN1 activity., PMID:24151046
Gastric autoantigenic proteins in Helicobacter pylori infection., PMID:24142637
For research use only. Not for human or drug use.
