Catalog No.
YHJ66201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu492-Ala738
Predicted molecular weight
29.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NRK6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
M-ABC2, ABC transporter 10 protein, Mitochondrial ATP-binding cassette 2, ATP-binding cassette sub-family B member 10, mitochondrial, ABCB10, ATP-binding cassette transporter 10
Conformational equilibrium of an ABC transporter analyzed by luminescence resonance energy transfer., PMID:39973007
Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome., PMID:39238930
Cardiomyocyte-specific deletion of the mitochondrial transporter Abcb10 causes cardiac dysfunction via lysosomal-mediated ferroptosis., PMID:38655715
Abcb10 regulates murine hematopoietic stem cell potential and erythroid differentiation., PMID:38493949
The mitochondrial biliverdin exporter ABCB10 in hepatocytes mitigates neutrophilic inflammation in alcoholic hepatitis., PMID:38290384
Congenital asplenia impairs heme-iron recycling during erythropoiesis in zebrafish., PMID:38040044
Cardiolipin Regulates the Activity of the Mitochondrial ABC Transporter ABCB10., PMID:37807693
Loss of the mitochondrial protein Abcb10 results in altered arginine metabolism in MEL and K562 cells and nutrient stress signaling through ATF4., PMID:37269954
Cryo-EM structures of mitochondrial ABC transporter ABCB10 in apo and biliverdin-bound form., PMID:37041204
Polymorphic renal transporters and cisplatin's toxicity in urinary bladder cancer patients: current perspectives and future directions., PMID:36650399
Circular RNA circ-ABCB10 Promotes Proliferation and Inhibits Apoptosis of Laryngeal Carcinoma by Inhibiting KLF6., PMID:35756421
Integrative analysis prioritizes the relevant genes and risk factors for chronic venous disease., PMID:35218958
Analysis of corticosteroid and antiepileptic drug treatment effects on heme biosynthesis mRNA expression in lower-grade gliomas: Potential implications for 5-ALA metabolization., PMID:35149260
CircRNA-ABCB10 promotes gastric cancer progression by sponging miR-1915-3p to upregulate RaC1., PMID:34987010
ABCB10 Loss Reduces CD4+ T Cell Activation and Memory Formation., PMID:34893527
Deletion of ABCB10 in beta-cells protects from high-fat diet induced insulin resistance., PMID:34823065
ATP-binding cassette transporters mediate differential biosynthesis of glycosphingolipid species., PMID:34597626
Circular RNA ABCB10 contributes to laryngeal squamous cell carcinoma (LSCC) progression by modulating the miR-588/CXCR4 axis., PMID:34015764
Characterization of intermediate-sized insertions using whole-genome sequencing data and analysis of their functional impact on gene expression., PMID:33978893
[Effects of silencing circRNA ABCB10 expression on biological properties of colorectal cancer cells]., PMID:33902207
Circular RNA ABCB10 promotes cell proliferation and invasion, but inhibits apoptosis via regulating the microRNA‑1271‑mediated Capn4/Wnt/β‑catenin signaling pathway in epithelial ovarian cancer., PMID:33760208
Circular RNA circ_ABCB10 in cancer., PMID:33746018
Circ-ABCB10 promotes growth and metastasis of nasopharyngeal carcinoma by upregulating ROCK1., PMID:33336739
Stimulation of the human mitochondrial transporter ABCB10 by zinc-mesoporphrin., PMID:33253225
Production of a human mitochondrial ABC transporter in E. coli., PMID:33069825
Circ-ABCB10 acts as an oncogene in glioma cells via regulation of the miR-620/FABP5 axis., PMID:32633377
CircABCB10 silencing inhibits the cell ferroptosis and apoptosis by regulating the miR-326/CCL5 axis in rectal cancer., PMID:32567935
Circular RNA ABCB10 promotes non-small cell lung cancer progression by increasing E2F5 expression through sponging miR-584-5p., PMID:32420810
Circ-ABCB10 Contributes to Paclitaxel Resistance in Breast Cancer Through Let-7a-5p/DUSP7 Axis., PMID:32273769
The Blood-Brain Barrier Interface in Diabetes Mellitus: Dysfunctions, Mechanisms and Approaches to Treatment., PMID:32209037
Circular RNA-ABCB10 suppresses hepatocellular carcinoma progression through upregulating NRP1/ABL2 via sponging miR-340-5p/miR-452-5p., PMID:32196586
Circ-ABCB10 accelerates the malignant progression of oral squamous cell carcinoma by absorbing miRNA-145-5p., PMID:32016969
Knockdown of circ-ABCB10 promotes sensitivity of lung cancer cells to cisplatin via miR-556-3p/AK4 axis., PMID:31931771
Circular RNA ABCB10 correlates with advanced clinicopathological features and unfavorable survival, and promotes cell proliferation while reduces cell apoptosis in epithelial ovarian cancer., PMID:31381507
Circular RNA ABCB10 promotes tumor progression and correlates with pejorative prognosis in clear cell renal cell carcinoma., PMID:31106654
Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability., PMID:30802639
Dimeric ferrochelatase bridges ABCB7 and ABCB10 homodimers in an architecturally defined molecular complex required for heme biosynthesis., PMID:30765471
Optimized protocols for studying the NLRP3 inflammasome and assessment of potential targets of CP-453,773 in undifferentiated THP1 cells., PMID:30735689
CircABCB10 promotes nonsmall cell lung cancer cell proliferation and migration by regulating the miR-1252/FOXR2 axis., PMID:30417418
Exposure to amitraz, fipronil and permethrin affects cell viability and ABC transporter gene expression in an Ixodes ricinus cell line., PMID:30064465
Reductions in the mitochondrial ABC transporter Abcb10 affect the transcriptional profile of heme biosynthesis genes., PMID:28808058
Predictive Structure and Topology of Peroxisomal ATP-Binding Cassette (ABC) Transporters., PMID:28737695
Blood-brain barrier disruption in diabetic mice is linked to Nrf2 signaling deficits: Role of ABCB10?, PMID:28572033
ABCB10 depletion reduces unfolded protein response in mitochondria., PMID:28315685
Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism., PMID:28031527
Valproic acid (VPA) enhances cisplatin sensitivity of non-small cell lung cancer cells via HDAC2 mediated down regulation of ABCA1., PMID:28002023
Exploiting Microbeams for Membrane Protein Structure Determination., PMID:27553238
BSA and ABCB1 polymorphism affect the pharmacokinetics of sunitinib and its active metabolite in Asian mRCC patients receiving an attenuated sunitinib dosing regimen., PMID:27485537
Identification of a novel β-adrenergic octopamine receptor-like gene (βAOR-like) and increased ATP-binding cassette B10 (ABCB10) expression in a Rhipicephalus microplus cell line derived from acaricide-resistant ticks., PMID:27484910
Evaluation of the in vitro expression of ATP binding-cassette (ABC) proteins in an Ixodes ricinus cell line exposed to ivermectin., PMID:27090214
For research use only. Not for human or drug use.
