Catalog No.
YHJ65401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Val512
Predicted molecular weight
59.82 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NR63
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CYP26A2, Cytochrome P450 26A2, CYP26B1, P450RAI2, Cytochrome P450 retinoic acid-inactivating 2, Retinoic acid-metabolizing cytochrome, Cytochrome P450RAI-2, Cytochrome P450 26B1
Retinoic acid breakdown is required for proximodistal positional identity during axolotl limb regeneration., PMID:40494878
The interictal transcriptomic map of migraine without aura., PMID:40350427
Meiosis and retinoic acid in the mouse fetal gonads: An unforeseen twist., PMID:39870439
Sulfur Dioxide Alleviates Aortic Dissection Through Inhibiting Vascular Smooth Muscle Cell Phenotype Switch, Migration, and Proliferation via miR-184-3p/Cyp26b1 Axis., PMID:39834177
Enhancing Retinoic Acid-mediated Effects Through Inhibition of CYP26A1, CYP26B1 and HGF Signaling in Neuroblastoma Cells., PMID:39348986
Retinoic acid-mediated homeostatic plasticity in the nucleus accumbens core contributes to incubation of cocaine craving., PMID:38935096
Development and validation of CYP26A1 inhibition assay for high-throughput screening., PMID:38863121
Cytochrome P450 enzymes in the black-spotted frog (Pelophylax nigromaculatus): molecular characterization and upregulation of expression by sulfamethoxazole., PMID:38784115
Gonadal Transcriptome Analysis Reveals that SOX17 and CYP26A1 are Involved in Sex Differentiation in the Chinese Soft-Shelled Turtle (Pelodiscus sinensis)., PMID:38710962
Identification of an inflammation-related risk signature for prognosis and immunotherapeutic response prediction in bladder cancer., PMID:38216619
Expression patterns of CYP26A1, FGF8, CDKN1A, and NPVF in the developing rhesus monkey retina., PMID:38147763
[Change of the retinoic acid pathway in hypothalamus and pituitary damage induced by combined exposure to low-level Pb~(2+) and 1-nitropyrene in mice]., PMID:38115665
Metformin reduces hepatocarcinogenesis by inducing downregulation of Cyp26a1 and CD8+ T cells., PMID:37997519
CLMP is a tumor suppressor that determines all-trans retinoic acid response in colorectal cancer., PMID:37944525
Elongation of the developing spinal cord is driven by Oct4-type transcription factor-mediated regulation of retinoic acid signaling in zebrafish embryos., PMID:37850839
CYP26B1-related disorder: expanding the ends of the spectrum through clinical and molecular evidence., PMID:37755482
Mechanism of thyroid hormone and its structurally similar contaminant bisphenol S exposure on retinoid metabolism in zebrafish larval eyes., PMID:37748373
Neural plate progenitors give rise to both anterior and posterior pituitary cells., PMID:37683631
Cytochrome P450 26A1 Contributes to the Maintenance of Neuropathic Pain., PMID:37639183
Hyperglycemia alters retinoic acid catabolism in embryos exposed to a maternal diabetic milieu., PMID:37616226
Molecular characterization and potential function of Rxrγ in gonadal differentiation of Chinese soft-shelled turtle (Pelodiscus sinensis)., PMID:37429547
Colitis-Mediated Dysbiosis of the Intestinal Flora and Impaired Vitamin A Absorption Reduce Ovarian Function in Mice., PMID:37299390
Familial monoallelic CYP26B1 truncating variant causes a syndromic craniosynostosis due to haploinsufficiency ?, PMID:37100236
A variant in CYP26B1 associated with esophageal squamous cell carcinoma risk by affecting retinoic acid metabolism., PMID:37042568
Genetic linkage analysis of head and neck cancer in a Spanish family., PMID:37026679
Cyp26a1 supports postnatal retinoic acid homeostasis and glucoregulatory control., PMID:37011860
Wnt/β-Catenin Promotes the Osteoblastic Potential of BMP9 Through Down-Regulating Cyp26b1 in Mesenchymal Stem Cells., PMID:37010733
The molecular phenotype of kisspeptin neurons in the medial amygdala of female mice., PMID:36843592
A Functional Polymorphism Downstream of Vitamin A Regulator Gene CYP26B1 Is Associated with Hand Osteoarthritis., PMID:36769350
Retinoic acid metabolism in cancer: potential feasibility of retinoic acid metabolism blocking therapy., PMID:36592231
Transcriptome sequencing reveals two subtypes of cortisol-secreting adrenocortical tumours in dogs and identifies CYP26B1 as a potential new therapeutic target., PMID:36582114
PARP1 Is a Prognostic Marker and Targets NFATc2 to Promote Carcinogenesis in Melanoma., PMID:36394458
Letrozole ameliorates liver fibrosis through the inhibition of the CTGF pathway and 17β-hydroxysteroid dehydrogenase 13 expression., PMID:36301364
In Vitro Transfection of Up-Regulated Genes Identified in Favorable-Outcome Neuroblastoma into Cell Lines., PMID:36231133
Identification and Expression Pattern of cyp26b1 Gene in Gonad of the Chinese Tongue Sole (Cynoglossus semilaevis)., PMID:36230393
Distinctive Metabolism-Associated Gene Clusters That Are Also Prognostic in Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma., PMID:36199423
Anterior Insula-Associated Social Novelty Recognition: Pivotal Roles of a Local Retinoic Acid Cascade and Oxytocin Signaling., PMID:36128683
All-trans Retinoic Acid has Limited Therapeutic Effects on Cognition and Hippocampal Protein Expression After Controlled Cortical Impact., PMID:35878718
CYP26A1 Is a Novel Cancer Biomarker of Pancreatic Carcinoma: Evidence from Integration Analysis and In Vitro Experiments., PMID:35707714
Comprehensive Molecular Analyses of a Macrophage-Related Gene Signature With Regard to Prognosis, Immune Features, and Biomarkers for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and the LASSO Algorithm., PMID:35693827
Development of an adenovirus-mediated reporter assay system to detect a low concentration of retinoic acid in MCF-7 cells., PMID:35650141
Oxytocin receptor behavioral effects and cell types in the bed nucleus of the stria terminalis., PMID:35636023
Pesticides Inhibit Retinoic Acid Catabolism in PLHC-1 and ZFL Fish Hepatic Cell Lines., PMID:35608517
Zebrafish caudal fin as a model to investigate the role of probiotics in bone regeneration., PMID:35577882
CRABPs Alter all-trans-Retinoic Acid Metabolism by CYP26A1 via Protein-Protein Interactions., PMID:35565751
Endothelial Cyp26b1 restrains murine heart valve growth during development., PMID:35364055
The multiciliated cells in Rathke's cleft express CYP26A1 and respond to retinoic acid in the pituitary., PMID:35316373
Cytochrome P450 26A1 regulates the clusters and killing activity of NK cells during the peri-implantation period., PMID:35297206
Developmental changes in gene expression and gonad morphology during sex differentiation in Atlantic salmon (Salmo salar)., PMID:35248662
For research use only. Not for human or drug use.
