Catalog No.
YHJ63901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu227-Thr493
Predicted molecular weight
54.75 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NPY3
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Matrix-remodeling-associated protein 4, C1q/MBL/SPA receptor, C1qRp, C1QR1, C1qR, Complement component 1 q subcomponent receptor 1, CD93, Complement component C1q receptor, MXRA4, CDw93, C1qR(p)
Blockade of the CD93 pathway normalizes tumor vasculature to facilitate drug delivery and immunotherapy，PMID: 34321321
Interleukin-17D regulates group 3 innate lymphoid cell function through its receptor CD93, PMID: 33852831
Structural and antigen-binding surface definition of an anti-CD93 monoclonal antibody for the treatment of degenerative vascular eye diseases., PMID:40228767
Comprehensive analysis of CLEC family genes in gastric cancer prognosis immune response and treatment., PMID:39966377
Expression and prognostic significance of CD93 in blood vessels in colorectal cancer: an immunohistochemical analysis of 134 cases., PMID:39962383
CD93 blockade promotes effector T-cell infiltration and facilitates adoptive cell therapy in solid tumors., PMID:39805660
Avian pathogenic Escherichia coli alters complement gene expression in chicken erythrocytes., PMID:39757946
CD93 aggravates cell proliferation, angiogenesis and immune escape in osteosarcoma through triggering the PI3K/AKT pathway., PMID:39542800
Immuno-PET Imaging of CD93 Expression with 64Cu-Radiolabeled NOTA-mCD93 ([64Cu]Cu-NOTA-mCD93) and Insulin-Like Growth Factor Binding Protein 7 ([64Cu]Cu-NOTA-IGFBP7)., PMID:39533706
Interleukin-17D accelerates atherosclerosis through promoting endothelial cells ferroptosis via CD93/miR-181a-5p/SLC7A11 signaling., PMID:39510035
[Relationship of cerebrospinal fluid and serum levels of SIL-2R, eNOS, and CD93 with the progression and prognosis of viral encephalitis in children]., PMID:39467677
Targeting CD93 on monocytes revitalizes antitumor immunity by enhancing the function and infiltration of CD8+ T cells., PMID:39448202
Exploring the hub Genes and Potential Mechanisms of Complement system-related Genes in Parkinson Disease: Based on Transcriptome Sequencing and Mendelian Randomization., PMID:39373800
Immune cells mediate the causal pathway linking circulating complements to cancer: A Mendelian randomization study., PMID:39352488
Lithium-induced apoptotic cell death is not accompanied by a noticeable inflammatory response in the kidney., PMID:39234304
Clinicopathological association of CD93 expression in gastric adenocarcinoma., PMID:39190192
IGFBP7 mediates oxLDL-induced human vascular endothelial cell injury by suppressing the expression of SIRT1., PMID:39170442
Systematic Druggable Genome-Wide Mendelian Randomization Identifies Therapeutic Targets for Functional Outcome After Ischemic Stroke., PMID:39119979
Identification of two key biomarkers CD93 and FGL2 associated with survival of acute myeloid leukaemia by weighted gene co-expression network analysis., PMID:39054581
Pathogen stimulations and immune cells synergistically affect the gene expression profile characteristics of porcine peripheral blood mononuclear cells., PMID:39054472
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity., PMID:38896451
First Trimester Placental Biomarkers for Pregnancy Outcomes., PMID:38892323
Enrichment of Bioactive Lipids in Urinary Extracellular Vesicles and Evidence of Apoptosis in Kidneys of Hypertensive Diabetic Cathepsin B Knockout Mice after Streptozotocin Treatment., PMID:38791000
Unveiling the role of IL-17: Therapeutic insights and cardiovascular implications., PMID:38735805
Proteomics on human cerebral cavernous malformations reveals novel biomarkers in neurovascular dysfunction for the disease pathology., PMID:38537685
CD93 regulates breast cancer growth and vasculogenic mimicry through the PI3K/AKT/SP2 signaling pathway activated by integrin β1., PMID:38511888
Effect of nonsteroidal anti-inflammatory drugs (aspirin and naproxen) on inflammation-associated proteomic profiles in mouse plasma and prostate during TMPRSS2-ERG (fusion)-driven prostate carcinogenesis., PMID:38506376
Group XIV C-type lectins: emerging targets in tumor angiogenesis., PMID:38468017
CD93 maintains endothelial barrier function and limits metastatic dissemination., PMID:38441970
Blockade of CD93 in pleural mesothelial cells fuels anti-lung tumor immune responses., PMID:38250037
Structural insight into CD93 recognition by IGFBP7., PMID:38218180
CL-K1 Promotes Complement Activation and Regulates Opsonophagocytosis of Macrophages with CD93 Interaction in a Primitive Vertebrate., PMID:38180157
Identification of Clinically Relevant Brain Endothelial Cell Biomarkers in Plasma., PMID:37814955
The C-Type Lectin Receptor CD93 Regulates Platelet Activation and Surface Expression of the Protease Activated Receptor 4., PMID:37669782
Phase I Results of Bromodomain and Extra-Terminal Inhibitor PLX51107 in Combination with Azacitidine in Patients with Relapsed/Refractory Myeloid Malignancies., PMID:37585491
Soluble CD93 lectin-like domain sequesters HMGB1 to ameliorate inflammatory diseases., PMID:37554277
CD93 overexpresses in liver hepatocellular carcinoma and represents a potential immunotherapy target., PMID:37483608
Role of CD93 in Health and Disease., PMID:37443812
Diagnostic and Prognostic Role of CD93 in Cardiovascular Disease: A Systematic Review., PMID:37371490
Structural insight into CD93 recognition by IGFBP7., PMID:37333140
Inflammatory Mesenchymal Stem Cells Express Abundant Membrane-Bound and Soluble Forms of C-Type Lectin-like CD248., PMID:37298499
CD93 Ameliorates Diabetic Wounds by Promoting Angiogenesis via the p38MAPK/MK2/HSP27 Axis., PMID:37295599
Extracellular vesicles from human plasma dampen inflammation and promote tissue repair functions in macrophages., PMID:37272889
Modelling the erythroblastic island niche of dyserythropoietic anaemia type IV patients using induced pluripotent stem cells., PMID:37113767
CD93 maintains endothelial barrier function by limiting the phosphorylation and turnover of VE-cadherin., PMID:36961390
Effect of avian influenza virus subtype H9N2 on the expression of complement-associated genes in chicken erythrocytes., PMID:36939295
The human cumulus cell transcriptome provides poor predictive value for embryo transfer outcome., PMID:36922313
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity., PMID:36891288
Multi-omics profiling and digital image analysis reveal the potential prognostic and immunotherapeutic properties of CD93 in stomach adenocarcinoma., PMID:36761750
Identification and validation of crucial lnc-TRIM28-14 and hub genes promoting gastric cancer peritoneal metastasis., PMID:36690975
Identify the immune characteristics and immunotherapy value of CD93 in the pan-cancer based on the public data sets., PMID:36389798
Bioinformatics Approaches to Predict Mutation Effects in the Binding Site of the Proangiogenic Molecule CD93., PMID:36353214
For research use only. Not for human or drug use.
