Catalog No.
YHJ63801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln649-Val837
Predicted molecular weight
47.60 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NPR2
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
KIAA1745, SEMA4B, Semaphorin-4B, SEMAC, Semaphorin-C
Genome-wide chromatin accessibility and transcriptome analysis reveal the up-regulation of immunosuppressive genes in macrophages under simulated microgravity., PMID:40280635
Gene-Environment Interaction Between CYP1B1 and Oral Contraception on Frontal Fibrosing Alopecia., PMID:38809548
Astrocyte-to-microglia communication via Sema4B-Plexin-B2 modulates injury-induced reactivity of microglia., PMID:38781210
Identification and Validation of Signature Genes and Their Correlations with Infiltrated Immune Cells in Neonatal Sepsis., PMID:37471663
The serum proteome of VA-ECMO patients changes over time and allows differentiation of survivors and non-survivors: an observational study., PMID:37173738
Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis., PMID:37121509
Identification of immune related gene signature for predicting prognosis of cholangiocarcinoma patients., PMID:36817485
Improved neuron protection following cortical injury in the absence of Semaphorin4B., PMID:36531136
Multiomics analysis reveals that hepatocyte nuclear factor 1β regulates axon guidance genes in the developing mouse kidney., PMID:36266461
CircSEMA4B inhibits the progression of breast cancer by encoding a novel protein SEMA4B-211aa and regulating AKT phosphorylation., PMID:36115854
Integrated proteomics and metabolomics analysis reveals hubs protein and network alterations in myasthenia gravis., PMID:35802752
Semaphorin 4B promotes tumor progression and associates with immune infiltrates in lung adenocarcinoma., PMID:35676688
Long non-coding RNA NEAT1 promotes the malignancy of laryngeal squamous cell carcinoma by regulating the microRNA-204-5p/SEMA4B axis., PMID:34630709
Intermittent fasting from dawn to sunset for four consecutive weeks induces anticancer serum proteome response and improves metabolic syndrome., PMID:33110154
Evaluation of predictive role of carcinoembryonic antigen and salivary mRNA biomarkers in gastric cancer detection., PMID:32481437
[New exploration of treatment target for proliferative diabetic retinopathy based on iTRAQ LC-MS/MS Proteomics]., PMID:31607066
Genome-wide meta-analysis implicates mediators of hair follicle development and morphogenesis in risk for severe acne., PMID:30542056
CircSEMA4B targets miR-431 modulating IL-1β-induced degradative changes in nucleus pulposus cells in intervertebral disc degeneration via Wnt pathway., PMID:30251693
Prostate cancer tissues with positive TMPRSS2-ERG-gene-fusion status may display enhanced nerve density., PMID:30241953
Regulation of antitumor miR-144-5p targets oncogenes: Direct regulation of syndecan-3 and its clinical significance., PMID:29968393
Combined shRNA over CRISPR/cas9 as a methodology to detect off-target effects and a potential compensatory mechanism., PMID:29311693
Identification of Key Genes in Colorectal Cancer Regulated by miR-34a., PMID:29197895
SEMA4B inhibits growth of non-small cell lung cancer in vitro and in vivo., PMID:25746385
SEMA4b inhibits MMP9 to prevent metastasis of non-small cell lung cancer., PMID:25095981
Hypoxia and hypoxia-inducible factor 1 repress SEMA4B expression to promote non-small cell lung cancer invasion., PMID:24474252
Label-free quantitative proteomics and N-glycoproteomics analysis of KRAS-activated human bronchial epithelial cells., PMID:22761399
Identification of semaphorin 4B as a negative regulator of basophil-mediated immune responses., PMID:21270411
Insertional mutagenesis by replication-deficient retroviral vectors encoding the large T oncogene., PMID:17395733
An RNAi-based approach identifies molecules required for glutamatergic and GABAergic synapse development., PMID:17224404
CLCP1 interacts with semaphorin 4B and regulates motility of lung cancer cells., PMID:17213806
Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif., PMID:15978582
Expression of semaphorins in developing and regenerating olfactory epithelium., PMID:10880988
For research use only. Not for human or drug use.
