Catalog No.
YHJ62101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val504-Ala766
Predicted molecular weight
30.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9NP78
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ATP-binding cassette transporter 9, ABC transporter 9 protein, ATP-binding cassette sub-family B member 9, hABCB9, TAP-like protein, ABCB9, KIAA1520, TAPL
Suppression of lysosome metabolism-meditated GARP/TGF-β1 complexes specifically depletes regulatory T cells to inhibit breast cancer metastasis., PMID:38698265
Genetic overlap between Alzheimer's disease and immune-mediated diseases: an atlas of shared genetic determinants and biological convergence., PMID:38499654
Identification of two novel heterodimeric ABC transporters in melanoma: ABCB5β/B6 and ABCB5β/B9., PMID:38145744
Genetic overlap between Alzheimer's disease and immune-mediated diseases: An atlas of shared genetic determinants and biological convergence., PMID:37841839
The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase., PMID:36195619
Genome-wide scanning for CHD1L gene in papillary thyroid carcinoma complicated with type 2 diabetes mellitus., PMID:34245428
An inventory of lysosomal ABC transporters., PMID:33098571
Peptide translocation by the lysosomal ABC transporter TAPL is regulated by coupling efficiency and activation energy., PMID:31417173
Dysregulation of placental ABC transporters in a murine model of malaria-induced preterm labor., PMID:31391498
ATP binding cassette subfamily B member 9 (ABCB9) is a prognostic indicator of overall survival in ovarian cancer., PMID:31083274
Lysosomal targeting of the ABC transporter TAPL is determined by membrane-localized charged residues., PMID:30877195
miR-196a Promotes Proliferation and Inhibits Apoptosis of Immature Porcine Sertoli Cells., PMID:30427699
MicroRNA-31-5p regulates chemosensitivity by preventing the nuclear location of PARP1 in hepatocellular carcinoma., PMID:30400960
Structural and functional insights into the interaction and targeting hub TMD0 of the polypeptide transporter TAPL., PMID:30353140
Identification and quantification of blood-brain barrier transporters in isolated rat brain microvessels., PMID:29675872
Chorioamnionitis Induces a Specific Signature of Placental ABC Transporters Associated with an Increase of miR-331-5p in the Human Preterm Placenta., PMID:29402780
RNA-sequencing dissects the transcriptome of polyploid cancer cells that are resistant to combined treatments of cisplatin with paclitaxel and docetaxel., PMID:28825433
Molecular dissection of Caenorhabditis elegans ATP-binding cassette transporter protein HAF-4 to investigate its subcellular localization and dimerization., PMID:28427936
Characterization of HAF-4- and HAF-9-localizing organelles as distinct organelles in Caenorhabditis elegans intestinal cells., PMID:26817689
The type 2 diabetes risk allele of TMEM154-rs6813195 associates with decreased beta cell function in a study of 6,486 Danes., PMID:25799151
Team work at its best – TAPL and its two domains., PMID:25719319
Single liposome analysis of peptide translocation by the ABC transporter TAPL., PMID:25646430
Unexpected lack of specificity of a rabbit polyclonal TAP-L (ABCB9) antibody., PMID:27335633
Dominant contribution of the proteasome and metalloproteinases to TAP-independent MHC-I peptide repertoire., PMID:24983205
MicroRNA-31 inhibits cisplatin-induced apoptosis in non-small cell lung cancer cells by regulating the drug transporter ABCB9., PMID:24099915
Conformational stabilization of the membrane embedded targeting domain of the lysosomal peptide transporter TAPL for solution NMR., PMID:24013930
Co-operative function and mutual stabilization of the half ATP-binding cassette transporters HAF-4 and HAF-9 in Caenorhabditis elegans., PMID:23458156
The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2., PMID:22641697
The role of ABC transporters in progression and clinical outcome of colorectal cancer., PMID:22294766
Hydroxyurea decreases gemcitabine resistance in pancreatic carcinoma cells with highly expressed ribonucleotide reductase., PMID:21926937
Transporter associated with antigen processing-like (ABCB9) stably expressed in Chinese hamster ovary-K1 cells is sorted to the microdomains of lysosomal membranes., PMID:21212514
The lysosomal polypeptide transporter TAPL: more than a housekeeping factor?, PMID:21194361
Tuning the cellular trafficking of the lysosomal peptide transporter TAPL by its N-terminal domain., PMID:20377823
Normal formation of a subset of intestinal granules in Caenorhabditis elegans requires ATP-binding cassette transporters HAF-4 and HAF-9, which are highly homologous to human lysosomal peptide transporter TAP-like., PMID:19403699
Functional dissection of transmembrane domains of human TAP-like (ABCB9)., PMID:18952056
Peptide specificity and lipid activation of the lysosomal transport complex ABCB9 (TAPL)., PMID:18434309
Biochemical characterization of transporter associated with antigen processing (TAP)-like (ABCB9) expressed in insect cells., PMID:18175933
Identification of a lysosomal peptide transport system induced during dendritic cell development., PMID:17977821
Intracellular peptide transporters in human--compartmentalization of the "peptidome"., PMID:16710701
Examination of drug resistance activity of human TAP-like (ABCB9) expressed in yeast., PMID:16554024
TAP and TAP-like--brothers in arms?, PMID:16525794
Molecular cloning of several rat ABC transporters including a new ABC transporter, Abcb8, and their expression in rat testis., PMID:16390497
Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9)., PMID:15863492
Membrane localization of transporter associated with antigen processing (TAP)-like (ABCB9) visualized in vivo with a fluorescence protein-fusion technique., PMID:15577206
Antigen targeting to CD11b allows efficient presentation of CD4+ and CD8+ T cell epitopes and in vivo Th1-polarized T cell priming., PMID:15528345
Detection of TAP family dimerizations by an in vivo assay in mammalian cells., PMID:15518576
The carboxyl terminal sequence of rat transporter associated with antigen processing (TAP)-like (ABCB9) is heterogeneous due to splicing of its mRNA., PMID:14709908
Regional variations in ABC transporter expression along the mouse intestinal tract., PMID:14679303
Gene organization of human transporter associated with antigen processing-like (TAPL, ABCB9): analysis of alternative splicing variants and promoter activity., PMID:13679046
Identification and characterization of a TAP-family gene in the lamprey., PMID:12679854
For research use only. Not for human or drug use.
