Catalog No.
YHJ61401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala201
Predicted molecular weight
23.86 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HDC5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
JPH1, JP-1, JP1, Junctophilin-1, Junctophilin type 1
Proteins of the Triadic Excitation-Contraction Coupling Complex in Skeletal Muscle., PMID:40097154
Knockdown of the jph-1 gene produces altered nervous system structure and impaired muscle endurance phenotypes in Caenorhabditis elegans., PMID:39381635
Loss-of-function variants in JPH1 cause congenital myopathy with prominent facial and ocular involvement., PMID:39209426
The Effects of Aging on Sarcoplasmic Reticulum-Related Factors in the Skeletal Muscle of Mice., PMID:38396828
Loss-of-function variants in JPH1 cause congenital myopathy with prominent facial involvement., PMID:38370827
Identification of Signature Genes in the PD-1 Relative Gastric Cancer Using a Combined Analysis of Gene Expression and Methylation Data., PMID:36568638
Huntingtin regulates calcium fluxes in skeletal muscle., PMID:36409218
Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence., PMID:35089322
The role of junctophilin proteins in cellular function., PMID:35001666
Caenorhabditis elegans junctophilin has tissue-specific functions and regulates neurotransmission with extended-synaptotagmin., PMID:33871019
A Transcriptomic Signature for Risk-Stratification and Recurrence Prediction in Intrahepatic Cholangiocarcinoma., PMID:33725402
Alterations in the Ca2+ toolkit in oesophageal adenocarcinoma., PMID:36046118
Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma., PMID:31748560
S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane., PMID:31337710
Molecular determinants of homo- and heteromeric interactions of Junctophilin-1 at triads in adult skeletal muscle fibers., PMID:31315980
Association of SNP in JPH1 gene with severity of disease in Charcot Marie Tooth 2K patients., PMID:30804591
The Drosophila junctophilin gene is functionally equivalent to its four mammalian counterparts and is a modifier of a Huntingtin poly-Q expansion and the Notch pathway., PMID:29208631
Organization of junctional sarcoplasmic reticulum proteins in skeletal muscle fibers., PMID:26374336
Genome-Wide Association Identifies SLC2A9 and NLN Gene Regions as Associated with Entropion in Domestic Sheep., PMID:26098909
Junctophilin-1 is a modifier gene of GDAP1-related Charcot-Marie-Tooth disease., PMID:25168384
Observation of the molecular organization of calcium release sites in fast- and slow-twitch skeletal muscle with nanoscale imaging., PMID:25100314
Novel genetic variants modify the effect of smoking on carotid plaque burden in Hispanics., PMID:24954085
An essential role for calcium flux in phagocytes for apoptotic cell engulfment and the anti-inflammatory response., PMID:19461656
Mutation of junctophilin type 2 associated with hypertrophic cardiomyopathy., PMID:17476457
For research use only. Not for human or drug use.
