Catalog No.
YHJ60501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met559-Leu880
Predicted molecular weight
38.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HCH5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Breast cancer-associated antigen SGA-72M, SYTL2, Synaptotagmin-like protein 2, SGA72M, SLP2, Exophilin-4, SLP2A, KIAA1597
[Alveolar Soft Part Sarcoma-The Angiogenic Mechanism Regulated by a Fusion Gene Product]., PMID:39009511
Mimicking angiogenic microenvironment of alveolar soft-part sarcoma in a microfluidic coculture vasculature chip., PMID:38502703
Lineage tracing of T cell differentiation from T-iPSC by 2D feeder-free culture and 3D organoid culture., PMID:38162650
Effects of COL1A1 and SYTL2 on inflammatory cell infiltration and poor extracellular matrix remodeling of the vascular wall in thoracic aortic aneurysm., PMID:37640670
SYTL2 promotes metastasis of prostate cancer cells by enhancing FSCN1-mediated pseudopodia formation and invasion., PMID:37147713
ASPSCR1::TFE3 orchestrates the angiogenic program of alveolar soft part sarcoma., PMID:37029109
mRNA Capture Sequencing and RT-qPCR for the Detection of Pathognomonic, Novel, and Secondary Fusion Transcripts in FFPE Tissue: A Sarcoma Showcase., PMID:36232302
Comprehensive profiling of 1015 patients' exomes reveals genomic-clinical associations in colorectal cancer., PMID:35487942
Synaptotagmin-Like Protein 2a Regulates Angiogenic Lumen Formation via Weibel-Palade Body Apical Secretion of Angiopoietin-2., PMID:33853352
In Vitro Fluorescence Resonance Energy Transfer-Based Assay Used to Determine the Rab27-Effector-Binding Affinity., PMID:32384245
Construction of prognostic risk prediction model of oral squamous cell carcinoma based on co-methylated genes., PMID:31198983
Genetic Study on Small Insertions and Deletions in Psoriasis Reveals a Role in Complex Human Diseases., PMID:31078570
Dermal mesenchymal stem cells: a resource of migration-associated function in psoriasis?, PMID:30760317
Stomatin-like protein 2 is involved in endometrial stromal cell proliferation and differentiation during decidualization in mice and humans., PMID:27986413
Synaptotagmin-like protein 2 gene promotes the metastatic potential in ovarian cancer., PMID:27220283
Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate., PMID:25940347
Slp2-a controls renal epithelial cell size through regulation of Rap-ezrin signaling independently of Rab27., PMID:24284068
Rab27 effector Slp2-a transports the apical signaling molecule podocalyxin to the apical surface of MDCK II cells and regulates claudin-2 expression., PMID:22767581
Deregulation of Rab and Rab effector genes in bladder cancer., PMID:22724020
SLP-2 is required for stress-induced mitochondrial hyperfusion., PMID:19360003
Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a., PMID:18940603
Dysferlin deficiency shows compensatory induction of Rab27A/Slp2a that may contribute to inflammatory onset., PMID:18832576
A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion., PMID:18812475
Purification, crystallization and preliminary X-ray crystallographic analysis of Rab27a GTPase in complex with exophilin4/Slp2-a effector., PMID:18607085
Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse., PMID:18266782
Physiological roles of Rab27 effectors in regulated exocytosis., PMID:17664848
Exophilin4/Slp2-a targets glucagon granules to the plasma membrane through unique Ca2+-inhibitory phospholipid-binding activity of the C2A domain., PMID:17182843
Decreased basal mucus secretion by Slp2-a-deficient gastric surface mucous cells., PMID:16716193
The usage of alternative splice sites in Mus musculus synaptotagmin-like 2 gene is modulated by cyclosporin A and FK506 in T-lymphocytes., PMID:16376427
Rab27A-binding protein Slp2-a is required for peripheral melanosome distribution and elongated cell shape in melanocytes., PMID:15543135
Muscle satellite cell-specific genes identified by genetic profiling of MyoD-deficient myogenic cell., PMID:15501219
The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain., PMID:11773082
Novel splicing isoforms of synaptotagmin-like proteins 2 and 3: identification of the Slp homology domain., PMID:11327731
Synaptotagmin-like protein 1-3: a novel family of C-terminal-type tandem C2 proteins., PMID:11243866
For research use only. Not for human or drug use.
