Catalog No.
YHJ58701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Gln180
Predicted molecular weight
23.23 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9HAV4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ran-binding protein 21, XPO5, RANBP21, Exportin-5, KIAA1291, Exp5
SARS-CoV-2 N protein exerts antitumor effects in NSCLC by inducing DNA damage and augmenting chemotherapeutic sensitivity., PMID:40451965
Sex-Biased Gene Expression of RNAi Pathway Components in the Sea Lice Caligus rogercresseyi., PMID:40347394
YTHDC1 phase separation drives the nuclear export of m6A-modified lncNONMMUT062668.2 through the transport complex SRSF3-ALYREF-XPO5 to aggravate pulmonary fibrosis., PMID:40221424
MicroRNA regulator gene mutations in thyroid follicular nodular disease and thyroid cancer: does it all come down to timing?, PMID:39601261
Relationship Between the Occurrence of Depression and DROSHA (rs6877842, rs10719) and XPO5 (rs11077) Single-Nucleotide Polymorphisms in the Polish Population: A Case-Control Study., PMID:39596271
AGO2 protein: a key enzyme in the miRNA pathway as a novel biomarker in adrenocortical carcinoma., PMID:39404265
SARS-CoV-2 N protein-induced Dicer, XPO5, SRSF3, and hnRNPA3 downregulation causes pneumonia., PMID:39138195
Single nucleotide polymorphisms of GEMIN3 modify the risk of primary Sjögren's syndrome in female patients., PMID:38969288
Parental experiences orchestrate locust egg hatching synchrony by regulating nuclear export of precursor miRNA., PMID:38773155
The relationship between prognosis of patients with traumatic brain injury and microRNA biogenesis proteins., PMID:37889026
Lipid kinase PIP5K1A regulates let-7 microRNA biogenesis through interacting with nuclear export protein XPO5., PMID:37655623
The role of the FSGS disease gene product and nuclear pore protein NUP205 in regulating nuclear localization and activity of transcriptional regulators YAP and TAZ., PMID:37565816
Pin1 inhibitor API-1 sensitizes BRAF-mutant thyroid cancers to BRAF inhibitors by attenuating HER3-mediated feedback activation of MAPK/ERK and PI3K/AKT pathways., PMID:37473892
Investigation of the association of the RAN (rs14035) and XPO5 (rs11077) polymorphisms with venous thromboembolism., PMID:37311119
Genes Involved in miRNA Biogenesis Are Not Downregulated in SARS-CoV-2 Infection., PMID:37243263
Identification of crucial genes involved in thyroid cancer development., PMID:37211566
Comprehensive bioinformatics analysis on exportins in lung adenocarcinoma and lung squamous cell carcinoma., PMID:37197486
Comparison of Pairwise Venous and Fingertip Plasma Using Quantitative Proteomics Based on Data-Independent Acquisition., PMID:36882937
LINC00543 promotes colorectal cancer metastasis by driving EMT and inducing the M2 polarization of tumor associated macrophages., PMID:36841801
Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Modulate miRNA Biogenesis through Aberrant Interactions with Exportin 5., PMID:36475596
Mutation in XPO5 causes adult-onset autosomal dominant familial focal segmental glomerulosclerosis., PMID:36371311
Establishment and verification of a prognostic model of liver cancer by RNA-binding proteins based on the TCGA database., PMID:36249884
MicroRNA biogenesis proteins follow tissue-dependent expression during freezing in Dryophytes versicolor., PMID:35748902
A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis., PMID:35484353
Regulation of XPO5 phosphorylation by PP2A in hepatocellular carcinoma., PMID:35441157
MicroRNA networks in FLT3-ITD acute myeloid leukemia., PMID:35412895
Inhibition of the antigen-presenting ability of dendritic cells by non-structural protein 2 of influenza A virus., PMID:35259598
Study of the inhibitory effect of STAT1 on PDCoV infection., PMID:35033844
The impact of Dicer, Drosha, and Exportin-5 levels in polycystic ovary syndrome (PCOS) diagnosis and phenotyping., PMID:34855193
Development and Validation of an RNA Binding Protein-associated Prognostic Model for Hepatocellular Carcinoma., PMID:34722178
Targeting miR-126 in inv(16) acute myeloid leukemia inhibits leukemia development and leukemia stem cell maintenance., PMID:34686664
Selectivity of Exportin 5 binding to human precursor microRNAs., PMID:34592896
Effects of Knockdown of XPO5 by siRNA on the Biological Behavior of Head and Neck Cancer Cells., PMID:34328643
Alteration of protein expression and spliceosome pathway activity during Barrett's carcinogenesis., PMID:34227026
TKI-Resistant Renal Cancer Secretes Low-Level Exosomal miR-549a to Induce Vascular Permeability and Angiogenesis to Promote Tumor Metastasis., PMID:34179017
HASTY, the Arabidopsis EXPORTIN5 ortholog, regulates cell-to-cell and vascular microRNA movement., PMID:34152631
A noncanonical microRNA derived from the snaR-A noncoding RNA targets a metastasis inhibitor., PMID:33795480
Cytoplasmic DROSHA and non-canonical mechanisms of MiR-155 biogenesis in FLT3-ITD acute myeloid leukemia., PMID:33589748
Individual and joint effects of genetic polymorphisms in microRNA-machinery genes on congenital heart disease susceptibility., PMID:33423710
Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer., PMID:33356812
Evolution of MicroRNA Biogenesis Genes in the Sterlet (Acipenser ruthenus) and Other Polyploid Vertebrates., PMID:33334059
Alteration of miRNA Biogenesis Regulating Proteins in the Human Microglial Cell Line HMC-3 After Ischemic Stress., PMID:33210205
Non-coding RNAs repressive role in post-transcriptional processing of RUNX2 during the acquisition of the osteogenic phenotype of periodontal ligament mesenchymal stem cells., PMID:33152274
Effect of neonatal exposure to endocrine-active compounds on epigenetic regulation of gene expression in corpus luteum of gilts., PMID:33113443
Analysis of microRNA processing machinery gene (DROSHA, DICER1, RAN, and XPO5) variants association with end-stage renal disease., PMID:32770606
Exportin-5 SUMOylation promotes hepatocellular carcinoma progression., PMID:32763246
LXR activation potentiates sorafenib sensitivity in HCC by activating microRNA-378a transcription., PMID:32754282
Dysregulation of microRNA expression in diabetic skin., PMID:32402513
XPO5 promotes primary miRNA processing independently of RanGTP., PMID:32296071
Association between microRNA machinery gene polymorphisms and recurrent implantation failure., PMID:32226488
For research use only. Not for human or drug use.
