Catalog No.
YHJ55901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg700-Leu918
Predicted molecular weight
26.19 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H2X0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Chordin, CHRD
PRDM14 is essential for vertebrate gastrulation and safeguards avian germ cell identity., PMID:39938772
Suppression of lysosome metabolism-meditated GARP/TGF-β1 complexes specifically depletes regulatory T cells to inhibit breast cancer metastasis., PMID:38698265
TGF-β Score based on Silico Analysis can Robustly Predict Prognosis and Immunological Characteristics in Lower-grade Glioma: The Evidence from Multicenter Studies., PMID:37718518
Expression Levels of the Tnni3k Gene in the Heart Are Highly Associated with Cardiac and Glucose Metabolism-Related Phenotypes and Functional Pathways., PMID:37628941
O-Fucosylation of BMP1 promotes endometrial decidualization by activating BMP/Smad signaling pathway., PMID:37338142
The developmental gene Chordin is amplified and expressed in human cancers., PMID:37260544
Dynamics of the personalities of PCSK9 on missense variants (rs505151 and rs562556) from elderly cohort studies in Brazil., PMID:37010997
Two Homeobox Transcription Factors, Goosecoid and Ventx1.1, Oppositely Regulate Chordin Transcription in Xenopus Gastrula Embryos., PMID:36980215
ccl19 and ccl21 affect cell movements and differentiation in early Xenopus development., PMID:36861303
SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2., PMID:36851576
New insight into long-term effects of phthalates microplastics in developing zebrafish: Evidence from genomic alteration and organ development., PMID:36841272
Molecular interactions of PCSK9 with an inhibitory nanobody, CAP1 and HLA-C: Functional regulation of LDLR levels., PMID:36566984
ccr7 affects both morphogenesis and differentiation during early Xenopus embryogenesis., PMID:35581152
RNA sequence analysis identified bone morphogenetic protein-2 (BMP2) as a biomarker underlying form deprivation myopia., PMID:35494490
Integrative analyses of biomarkers and pathways for heart failure., PMID:35346191
The landscape of promoter-centred RNA-DNA interactions in rice., PMID:35115727
PCSK9 regulates the NODAL signaling pathway and cellular proliferation in hiPSCs., PMID:34739847
Foxd4l1.1 Negatively Regulates Chordin Transcription in Neuroectoderm of Xenopus Gastrula., PMID:34685759
Expression profiling of ovarian BMP antagonists reveals the potential interaction between TWSG1 and the chordin subfamily in the ovary., PMID:34517078
BMP antagonists in tissue development and disease., PMID:34435185
The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes., PMID:33980237
Smad2 and Smad3 differentially modulate chordin transcription via direct binding on the distal elements in gastrula Xenopus embryos., PMID:33945994
Epicardial Adipose Tissue Accumulation Confers Atrial Conduction Abnormality., PMID:32883413
Thymosin β4 Identified by Transcriptomic Analysis from HF Anagen to Telogen Promotes Proliferation of SHF-DPCs in Albas Cashmere Goat., PMID:32218218
The effects of type I collagen on bone defects and gene expression changes for osteogenesis: In a rat model., PMID:30816601
Gremlin, noggin, chordin and follistatin differentially modulate BMP-induced suppression of androgen secretion by bovine ovarian theca cells., PMID:30400042
Effects of acute and chronic methamphetamine administration on cynomolgus monkey hippocampus structure and cellular transcriptome., PMID:29802913
Enhancer adoption caused by genomic insertion elicits interdigital Shh expression and syndactyly in mouse., PMID:29255029
Isolation and characterization of a stress-responsive gene encoding a CHRD domain-containing protein from a halotolerant green alga., PMID:29017964
The BMP2 variant L51P restores the osteogenic differentiation of human mesenchymal stromal cells in the presence of intervertebral disc cells., PMID:28266688
Spore surface proteins of Brevibacillus laterosporus are involved in insect pathogenesis., PMID:28256631
Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation., PMID:27848974
BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2., PMID:27385727
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation., PMID:27284008
De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects., PMID:27058611
Osteogenic differentiation of bone marrow stromal cells is hindered by the presence of intervertebral disc cells., PMID:26809343
Electrophysiological, Electroanatomical, and Structural Remodeling of the Atria as Consequences of Sustained Obesity., PMID:26139051
A semi-automated mass spectrometric immunoassay coupled to selected reaction monitoring (MSIA-SRM) reveals novel relationships between circulating PCSK9 and metabolic phenotypes in patient cohorts., PMID:25770357
Successful catheter ablation decreases platelet activation and improves endothelial function in patients with atrial fibrillation., PMID:25068571
Biomarkers and atrial fibrillation: is it prime time yet?, PMID:24846972
The M2 module of the Cys-His-rich domain (CHRD) of PCSK9 protein is needed for the extracellular low-density lipoprotein receptor (LDLR) degradation pathway., PMID:23105118
Chromatin dynamics in living cells: identification of oscillatory motion., PMID:22886456
Microarray expression analysis of genes and pathways involved in growth plate cartilage injury responses and bony repair., PMID:22387305
Identification and regulation of bone morphogenetic protein antagonists associated with preantral follicle development in the ovary., PMID:21791559
The expression of twisted gastrulation in postnatal mouse brain and functional implications., PMID:20493240
Distinct functionalities of bone morphogenetic protein antagonists during fracture healing in mice., PMID:20298438
Chromatin dynamics is correlated with replication timing., PMID:19296120
PCSK9 as a therapeutic target of dyslipidemia., PMID:19063703
PerioGlas regulates osteoblast RNA interfering., PMID:18573151
BMP antagonism is required in both the node and lateral plate mesoderm for mammalian left-right axis establishment., PMID:18550712
For research use only. Not for human or drug use.
