Catalog No.
YHJ55801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala528-Thr782
Predicted molecular weight
55.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9H2P0
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADNP1, Activity-dependent neuroprotector homeobox protein, ADNP, KIAA0784, Activity-dependent neuroprotective protein
Fc-effector functional antibody assays for SARS-CoV-2 variants of concern., PMID:40463385
Neuron-targeted caveolin-1 overexpression attenuates cognitive loss and pathological transcriptome changes in symptomatic Alzheimer's disease models., PMID:40425572
Intrinsically Disordered Regions Define Unique Protein Interaction Networks in CHD Family Remodelers., PMID:40372282
Artificial intelligence-driven genotype-epigenotype-phenotype approaches to resolve challenges in syndrome diagnostics., PMID:40280028
Intranasal NAP (Davunetide): Neuroprotection and circadian rhythmicity., PMID:40185278
Proteomic analysis reveals chromatin remodeling as a potential therapeutical target in neuroblastoma., PMID:40011918
Axonal motor polyneuropathy in a 13 years old Girl with a de Novo variant in ADNP., PMID:39992398
Transcriptomic Analysis Uncovers an Unfolded Protein Response in ADNP Syndrome., PMID:39950682
A guide to selecting high-performing antibodies for ADNP (UniProt ID: Q9H2P0) for use in western blot, immunoprecipitation, and immunofluorescence., PMID:39949964
Discovery of a DNA methylation profile in individuals with Sifrim-Hitz-Weiss syndrome., PMID:39824190
The chromatin remodeler ADNP regulates neurodevelopmental disorder risk genes and neocortical neurogenesis., PMID:39808658
Multifaceted Role of Specialized Neuropeptide-Intensive Neurons on the Selective Vulnerability to Alzheimer's Disease in the Human Brain., PMID:39766225
Proteomics reveals the key transcription-related factors mediating obstructive nephropathy in pediatric patients and mice., PMID:39743726
Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults., PMID:39723823
CHD6 eviction of promoter nucleosomes maintains housekeeping transcriptional program in prostate cancer., PMID:39717618
ADNP is essential for sex-dependent hippocampal neurogenesis, through male unfolded protein response and female mitochondrial gene regulation., PMID:39715923
Remote monitoring of social attention in neurogenetic syndromes and idiopathic neurodevelopmental disability., PMID:39643599
CoronaVac-induced antibodies that facilitate Fc-mediated neutrophil phagocytosis track with COVID-19 disease resolution., PMID:39584817
Quantifying neurobehavioral profiles across neurodevelopmental genetic syndromes and idiopathic neurodevelopmental disorders., PMID:39526825
Transcriptomic alterations in APP/PS1 mice astrocytes lead to early postnatal axon initial segment structural changes., PMID:39485512
Elucidating the roles of SOD3 correlated genes and reactive oxygen species in rare human diseases using a bioinformatic-ontology approach., PMID:39480826
Correction to: ADNP dysregulates methylation and mitochondrial gene expression in the cerebellum of a Helsmoortel-Van Der Aa syndrome autopsy case., PMID:39449121
Generation of a human induced pluripotent stem cell line (FDIBSi001-A) from a patient with ADNP syndrome carrying ADNP mutation (c. 2059 T>C)., PMID:39307104
Genetic and Environmental Factors Co-Contributing to Behavioral Abnormalities in adnp/adnp2 Mutant Zebrafish., PMID:39273418
Aortic Root Dilation and Genotype Associations in Phelan-McDermid Syndrome., PMID:39257296
Sex-Specific ADNP/NAP (Davunetide) Regulation of Cocaine-Induced Plasticity., PMID:39251453
Helsmoortel-Van der Aa syndrome in a 13-year-old girl with autistic spectrum disorder, dysmorphism, a right solitary kidney, and polycystic ovaries: a case report., PMID:39232847
Potential utility of ADNP in circulating tumor cells as biomarker for prognostics in non-muscle-invasive bladder cancer., PMID:39169215
Hypoxia-inducible factor 1alpha and vascular endothelial growth factor in Glioblastoma Multiforme: a systematic review going beyond pathologic implications., PMID:39055895
Transient peripheral blood transcriptomic response to ketamine treatment in children with ADNP syndrome., PMID:39054328
ChAHP2 and ChAHP control diverse retrotransposons by complementary activities., PMID:38960717
Tracing the invisible mutant ADNP protein in Helsmoortel-Van der Aa syndrome patients., PMID:38926592
Blepharophimosis with intellectual disability and Helsmoortel-Van Der Aa Syndrome share episignature and phenotype., PMID:38884529
Analyzing Immune Cell Infiltration and Copper Metabolism in Diabetic Foot Ulcers., PMID:38774446
Integrated ribosome and proteome analyses reveal insights into sevoflurane-induced long-term social behavior and cognitive dysfunctions through ADNP inhibition in neonatal mice., PMID:38766748
Moderate Physical Activity Increases the Expression of ADNP in Rat Brain., PMID:38673966
ADNP dysregulates methylation and mitochondrial gene expression in the cerebellum of a Helsmoortel-Van der Aa syndrome autopsy case., PMID:38637827
Shared and divergent mental health characteristics of ADNP-, CHD8- and DYRK1A-related neurodevelopmental conditions., PMID:38622540
Identification of a molecular network regulated by multiple ASD high risk genes., PMID:38588587
ADNP modulates SINE B2-derived CTCF-binding sites during blastocyst formation in mice., PMID:38479840
Loss-of-function of activity-dependent neuroprotective protein (ADNP) by a splice-acceptor site mutation causes Helsmoortel-Van der Aa syndrome., PMID:38424297
Transient peripheral blood transcriptomic response to ketamine treatment in children with ADNP syndrome., PMID:38352457
Longitudinal Genotype-Phenotype (Vineland Questionnaire) Characterization of 15 ADNP Syndrome Cases Highlights Mutated Protein Length and Structural Characteristics Correlation with Communicative Abilities Accentuated in Males., PMID:38282129
Clinical impact and in vitro characterization of ADNP variants in pediatric patients., PMID:38254177
Extended phenotypic characterization of a novel Helsmoortel-van der Aa syndrome case series., PMID:38204290
Osteocalcin activates lipophagy via the ADPN-AMPK/PPARα-mTOR signaling pathway in chicken embryonic hepatocyte., PMID:38070403
Multifaceted impact of specialized neuropeptide-intensive neurons on the selective vulnerability in Alzheimer's disease., PMID:38014130
ZMYM2 controls human transposable element transcription through distinct co-regulatory complexes., PMID:37934570
[Helsmoortel-Van der Aa syndrome due to hotspot mutation of ADNP gene and a literature review]., PMID:37906146
Fc-mediated functions of nirsevimab complement direct respiratory syncytial virus neutralization but are not required for optimal prophylactic protection., PMID:37901217
For research use only. Not for human or drug use.
