Catalog No.
YHJ51701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys259-Lys514
Predicted molecular weight
30.54 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BYV1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Alanine--glyoxylate aminotransferase 2, mitochondrial, D-AIBAT, Beta-ALAAT II, AGT2, (R)-3-amino-2-methylpropionate--pyruvate transaminase, Beta-alanine-pyruvate aminotransferase, AGXT2, AGT 2
A synthesis and quantification method for endogenous metabolites dimethylguanidino valeric acid., PMID:40169761
Symmetric dimethylguanidino valeric acid, a novel single biomarker of hepatic steatosis., PMID:39660051
AGXT2 Suppresses the Proliferation and Dissemination of Hepatocellular Carcinoma Cells by Modulating Intracellular Lipid Metabolism., PMID:39206420
Preliminary Study on the Pathogenic Mechanism of Jujube Flower Disease in Honeybees (Apis mellifera ligustica) Based on Midgut Transcriptomics., PMID:38790162
Quantitative proteomics analysis based on data-independent acquisition reveals the effect of Shenling Baizhu powder (SLP) on protein expression in MAFLD rat liver tissue., PMID:38036981
Identification of potential biomarkers and candidate therapeutic drugs for clear cell renal cell carcinoma by bioinformatic analysis and reverse network pharmacology., PMID:37657024
Whole-exome sequencing in moyamoya patients of Northern-European origin identifies gene variants involved in Nitric Oxide metabolism: A pilot study., PMID:37383439
Identification of AGXT2, SHMT1, and ACO2 as important biomarkers of acute kidney injury by WGCNA., PMID:36735737
DMGV Is a Rheostat of T Cell Survival and a Potential Therapeutic for Inflammatory Diseases and Cancers., PMID:35990633
iTRAQ-based quantitative proteomic analysis reveals the toxic mechanism of diclofenac sodium on the kidney of broiler chicken., PMID:34229076
The role of alanine glyoxylate transaminase-2 (agxt2) in β-alanine and carnosine metabolism of healthy mice and humans., PMID:32948897
Analysis of plasma metabolic profile, characteristics and enzymes in the progression from chronic hepatitis B to hepatocellular carcinoma., PMID:32701483
Nutritional and metabolic regulation of the metabolite dimethylguanidino valeric acid: an early marker of cardiometabolic disease., PMID:32663097
Three novel hub genes and their clinical significance in clear cell renal cell carcinoma., PMID:31839812
Kidney and liver are the main organs of expression of a key metabolic enzyme alanine:glyoxylate aminotransferase 2 in humans., PMID:31818439
Severe child form of primary hyperoxaluria type 2 - a case report revealing consequence of GRHPR deficiency on metabolism., PMID:28569194
Effect of l-arginine, asymmetric dimethylarginine, and symmetric dimethylarginine on ischemic heart disease risk: A Mendelian randomization study., PMID:27914500
Diabetes-linked transcription factor HNF4α regulates metabolism of endogenous methylarginines and β-aminoisobutyric acid by controlling expression of alanine-glyoxylate aminotransferase 2., PMID:27752141
Carnosine and anserine homeostasis in skeletal muscle and heart is controlled by β-alanine transamination., PMID:27062388
Asymmetric dimethylarginine is transported by the mitochondrial carrier SLC25A2., PMID:26403849
Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine., PMID:25245031
Alanine-glyoxylate aminotransferase 2 (AGXT2) polymorphisms have considerable impact on methylarginine and β-aminoisobutyrate metabolism in healthy volunteers., PMID:24586340
Pharmacology and clinical pharmacology of methylarginines used as inhibitors of nitric oxide synthases., PMID:24180385
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality., PMID:24159190
Nitric oxide synthase inhibition and oxidative stress in cardiovascular diseases: possible therapeutic targets?, PMID:23859953
Probing AGXT2 enzyme activity in mouse tissue by applying stable isotope-labeled asymmetric dimethyl arginine as substrate., PMID:23280748
A genome-wide association study of metabolic traits in human urine., PMID:21572414
Human alanine-glyoxylate aminotransferase 2 lowers asymmetric dimethylarginine and protects from inhibition of nitric oxide production., PMID:20018850
For research use only. Not for human or drug use.
