Catalog No.
YHJ49801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu22-Arg450
Predicted molecular weight
51.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9BU40
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neurogenesin-1, Ventroptin, Chordin-like protein 1, CHRDL1, Neuralin-1, NRLN1
Comprehensive pan-cancer analysis of CHRDL1 and experimental validation of its role in lung adenocarcinoma., PMID:40287623
Discovery of Lipid Metabolism Networks as Key Pathways in Breast Cancer via Genomic Data Integration and WGCNA., PMID:40209785
Depletion of marrow adipo-CAR cells in mice enhances bone formation by activating bone morphogenetic protein receptor (BMPR) in pre-osteoblasts., PMID:40156928
X-Linked Gene Dosage and SOX2 Act as Key Roadblocks for Human Germ Cell Specification in Klinefelter Syndrome., PMID:39996497
CHRDL1 inhibits OSCC metastasis via MAPK signaling-mediated inhibition of MED29., PMID:39462350
Proteomics of left ventricular structure in the Multi-Ethnic Study of Atherosclerosis., PMID:39263947
Chrdl1-mediated BMP4 inhibition disrupts the balance between retinal neurons and Müller Glia., PMID:39152126
Identification of an Exosome-relevant SNHG6-hsa-miR-429- CHRDL1/CCNA2 Axis for Lung Adenocarcinoma Prognosis Evaluation., PMID:38994652
Lipolysis-Stimulated Lipoprotein Receptor in Proximal Tubule, BMP-SMAD Signaling, and Kidney Disease., PMID:38809616
Effect of CHRDL1 on angiogenesis and metastasis of colorectal cancer cells via TGF-β/VEGF pathway., PMID:38415870
Identification of tumor-suppressor genes in lung squamous cell carcinoma through integrated bioinformatics analyses., PMID:38188687
Bioinformatics Analysis Reveals Novel Differentially Expressed Genes Between Ectopic and Eutopic Endometrium in Women with Endometriosis., PMID:37916013
Identification of autophagy and angiogenesis modulators in colorectal cancer based on bioinformatics analysis., PMID:37791824
CHRDL1, NEFH, TAGLN and SYNM as novel diagnostic biomarkers of benign prostatic hyperplasia and prostate cancer., PMID:37781794
Absence of chordin-like 1 aids motor recovery in a mouse model of stroke., PMID:37769794
Mechanisms of Regulation of the CHRDL1 Gene by the TWIST2 and ADD1/SREBP1c Transcription Factors., PMID:37761873
The unique role of bone marrow adipose tissue in ovariectomy-induced bone loss in mice., PMID:37682419
A prognostic model based on regulatory T-cell-related genes in gastric cancer: Systematic construction and validation., PMID:37350375
Bioinformatics Analysis of Differentially Expressed Genes in Ischemic Cardiomyopathy Using GEO Database., PMID:37213148
Chordin-like 1, a Novel Adipokine, Markedly Promotes Adipogenesis and Lipid Accumulation., PMID:36831292
Bioinformatics identify the role of chordin-like 1 in thyroid cancer., PMID:36749222
Chordin Like-1 Regulates Osteoblast and Adipocyte Differentiation Through Stabilizing Insulin-Like Growth Factor Binding Protein 3., PMID:36682027
CHRDL1 Regulates Stemness in Glioma Stem-like Cells., PMID:36497175
Glial progenitor cells of the adult human white and grey matter are contextually distinct., PMID:36334067
Cardioprotective factors against myocardial infarction selected in vivo from an AAV secretome library., PMID:36044596
Context-dependent tumor-suppressive BMP signaling in diffuse intrinsic pontine glioma regulates stemness through epigenetic regulation of CXXC5., PMID:35915262
RUNX2 Regulates Osteoblast Differentiation via the BMP4 Signaling Pathway., PMID:35619284
Study on the expression and function of chordin-like 1 in oral squamous cell carcinoma., PMID:35510812
Chordin-Like 1 Regulates Epithelial-to-Mesenchymal Transition and Metastasis via the MAPK Signaling Pathway in Oral Squamous Cell Carcinoma., PMID:35494000
Identification of differentially expressed and methylated genes and construction of a co-expression network in age-related macular degeneration., PMID:35280389
Astrocyte-secreted chordin-like 1 regulates spine density after ischemic injury., PMID:35264691
Chordin-like 1 is a novel prognostic biomarker and correlative with immune cell infiltration in lung adenocarcinoma., PMID:35021154
Novel CHRDL1 mutation causing X-linked megalocornea in a family with mild anterior segment manifestations in carrier females., PMID:34844512
BMP-2 Induced Signaling Pathways and Phenotypes: Comparisons Between Senescent and Non-senescent Bone Marrow Mesenchymal Stem Cells., PMID:34714366
Expression profiling of ovarian BMP antagonists reveals the potential interaction between TWSG1 and the chordin subfamily in the ovary., PMID:34517078
Distinguishing colorectal adenoma from hyperplastic polyp by WNT2 expression., PMID:34477243
Overexpression of BMP4 protects retinal ganglion cells in a mouse model of experimental glaucoma., PMID:34390734
Identification of hub genes in thyroid carcinoma to predict prognosis by integrated bioinformatics analysis., PMID:34167437
Low expression of CHRDL1 and SPARCL1 predicts poor prognosis of lung adenocarcinoma based on comprehensive analysis and immunohistochemical validation., PMID:33980221
Bioinformatics analysis of the molecular mechanism of obesity in polycystic ovary syndrome., PMID:33910166
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices., PMID:33846329
Identification of a Six Gene Prognosis Signature for Papillary Thyroid Cancer Using Multi-Omics Methods and Bioinformatics Analysis., PMID:33816258
Identification of differentially expressed genes and signaling pathways in papillary thyroid cancer: a study based on integrated microarray and bioinformatics analysis., PMID:33708546
Lycium barbarum polysaccharide (LBP) inhibits palmitic acid (PA)-induced MC3T3-E1 cell apoptosis by regulating miR-200b-3p/Chrdl1/PPARγ., PMID:33447177
Integrated microarray analysis to identify potential biomarkers and therapeutic targets in dilated cardiomyopathy., PMID:32626989
Association between circulating follistatin-like-1 and metabolic syndrome in middle-aged and old population: A cross-sectional study., PMID:32592413
Ocular Manifestations of Chordin-like 1 Knockout Mice., PMID:32452990
The miR-532-3p/Chrdl1 axis regulates the proliferation and migration of amniotic fluid-derived mesenchymal stromal cells., PMID:32446365
Identification of Potential Biomarkers for Thyroid Cancer Using Bioinformatics Strategy: A Study Based on GEO Datasets., PMID:32337286
Chordin-Like 1 Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells Through Enhancing BMP4-SMAD Pathway., PMID:31249554
For research use only. Not for human or drug use.
